Clinical trials: Anxiety and Fear
Anxiety, Fear Extinction
Uncovering Neurocognitive Mechanisms and Enhancement of Exposure-based Fear Learning With Cognitive Training
Anxiety disorders remain are among the most prevalent psychiatric conditions and are associated with negative outcomes spanning poor health to increased suicide risk.
- Trial name
- NCT07805070
- Testing
- Cognitive training
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Cesarean Section
The Effect of Pre-Cesarean Section Guided Imagery
The aim of this study is to evaluate the effect of guided imagery applied before cesarean section on preoperative anxiety, fear and physiological parameters. The study will be carried out in two different groups.
- Trial name
- NCT05790954
- Testing
- Guided imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menekşe Nazlı AKER
Anxiety, Surgical Fear
Effects of Preoperative Virtual Reality on Surgical Fear and Anxiety in Patients
Preoperative fear and anxiety are common among patients undergoing orthopedic surgery and may adversely affect perioperative outcomes.
- Conditions
- Anxiety, Surgical Fear, Surgical Fear Scale
- Trial name
- NCT07878039
- Testing
- Virtual Reality (VR) Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Karabuk University
Pain, Pediatric Patient
The Impact of Virtual Reality and Kaleidoscope in Children During Vaccination
This study was designed to examine the effects of using virtual reality and kaleidoscope during routine vaccination in children aged 48 months on pain, fear, and anxiety.
- Conditions
- Pain, Pediatric Patient, Fear, Virtual Reality
- Trial name
- NCT06112600
- Testing
- VR, Kaleidoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ege University
Anxiety, Stress, Psychological
Virtual Reality-Based 360° Clinic Walkthrough for Reducing Examination Anxiety in Preschool Children
This prospective, double-blind, randomized controlled trial investigates whether a short, 360° virtual reality (VR) pre-examination walkthrough can reduce anxiety, behavioral distress, and physiological stress responses in…
- Conditions
- Anxiety, Stress, Psychological, Fear
- Trial name
- NCT07255365
- Testing
- irtual Reality 360° Clinic Walkthrough
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Berker Okay
Non Specific Low Back Pain
Effects of Pain Neuroscience Education on Pain, Kinesiophobia in Patients With Non Specific Low Back Pain
Chronic non-specific low back pain (NSLBP) is a highly prevalent musculoskeletal condition and a leading cause of disability worldwide.
- Trial name
- NCT07460011
- Testing
- Core stabilization exercises, Pain neuroscience education + core stabilization
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Depression, Anxiety and Fear
Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
Over 50% of patients with major depressive disorder (MDD) do not respond to initial treatment and relapse is common. In particular, comorbid depression and anxiety disorders are associated with more treatment resistance.
- Trial name
- NCT04948944
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Early-stage Breast Cancer, Fear of Cancer Recurrence
Psilocybin FCR Early-Stage Breast Cancer
This trial is designed to evaluate efficacy and psychological mechanisms of single-dose psilocybin-assisted psychotherapy (PAP) to treat fear of cancer recurrence (FCR), psychiatric (anxiety, depression) distress and…
- Conditions
- Early-stage Breast Cancer, Fear of Cancer Recurrence, Anxiety, Depression
- Trial name
- NCT07909408
- Testing
- Psilocybin 25 mg, Psilocybin 5 mg
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Cesarean Section, Preoperative Anxiety
Effect of Emotional Freedom Technique on Surgical Fear and Vital Signs in Women Undergoing Cesarean Section
Surgical interventions are unusual interventions that can cause anxiety and fear in individuals. It is known that anxiety and fear experienced during this period affect the intraoperative and postoperative process.
- Trial name
- NCT07156279
- Testing
- EFT(Emotional Freedom Technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bingol University
Procedural Pain, Procedural Fear
Social Robot Interaction on Fear and Pain Levels in Children
The goal of this clinical trial is to compare the effectiveness of social robot interaction and digital game-based distraction in reducing fear and pain during venous blood sampling in children aged 4-12 years with chronic…
- Trial name
- NCT07632625
- Testing
- Social Robot, Digital Game
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Procedural Pain, Fear
Effects of Virtual Reality, External Cold and Vibration to Children During IM Injection on Pain, Fear and Anxiety
A randomized controlled trial is conducted to evaluation of the effects of virtual reality and local cold-vibration applications in reducing anxiety, fear and pain due to intramuscular (IM) injection in children aged 5-10 years.
- Conditions
- Procedural Pain, Fear, Procedural Anxiety, Child, Only
- Trial name
- NCT05434832
- Testing
- Virtual Reality, Local cold-vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Sleep Disturbance, Insomnia
The CANabidiol Use for RElief of Short Term Insomnia
This study aims to investigate the effect of 50 mg and 100 mg per day oral CBD product versus a placebo over 8 weeks on insomnia severity in adults aged 18-65 years old with insomnia symptoms.
- Conditions
- Sleep Disturbance, Insomnia, Insomnia Type; Sleep Disorder, Insomnia, Transient
- Trial name
- CANREST (NCT05253417)
- Testing
- 50 mg Cannabidiol (CBD), 100 mg Cannabidiol (CBD)
- Where
- 2 sites in Australia
- Volunteers
- 208 people
- Sponsor
- Bod Australia
COPD, Kinesiophobia Due to Dyspnea
Clinical Variables and Dyspnea and Fear of Movement in Chronic Obstructive Pulmonary Patients
Patients diagnosed with COPD who applied to the Pulmonary Diseases Department of Kırıkkale Yüksek İhtisas Hospital will be included in the study.
- Trial name
- NCT06442059
- Testing
- Kinesiophobia Level Due to Dyspnea
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kırıkkale University
Fibromyalgia
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
The goal of this clinical trial is to learn if a digital sleep therapy program (digital Cognitive Behavioural Therapy for Insomnia or dCBT-I) works to improve quality of life and movement in adults with fibromyalgia who also have…
- Trial name
- PainLESS-2 (NCT07465991)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia, Sleep Hygiene Education Materials
- Where
- 2 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- University of Oxford
Kinesiophobia (Fear of Movement), Experimental Pain
Pain Beliefs and Intracortical Excitability During Experimental Pain
Pain can influence the way the motor system functions. However, responses to pain vary widely between individuals, and this variability may be partly related to pain-related beliefs such as kinesiophobia.
- Trial name
- NCT07688525
- Testing
- Topical Capsaicin Cream (1%)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Fear of Pain, Knee Osteoarthritis
Knee Osteoarthritis, Kinesiophobia and Physical Activity
Although the importance of regular physical activity in patients with knee osteoarthritis is known, and fear of movement is considered as one of the causes of physical inactivity and is widely researched in terms of its role in…
- Conditions
- Fear of Pain, Knee Osteoarthritis, Physical Activity
- Trial name
- NCT03875040
- Testing
- kinesiophobia
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Aksaray University Training and Research Hospital
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Procedural Anxiety, Fear
Effects of Virtual Reality, Cold-Vibration Due To Intravenous Catheterization on Pain, Fear and Anxiety on Children
This is a randomized controlled trial. The aim of the study is to the effects of Virtual Reality and Local Cold-Vibration applications in reducing anxiety, fear and pain due to intravenous catheterization (PIC) in children aged…
- Conditions
- Procedural Anxiety, Fear, Procedural Pain, Child, Only
- Trial name
- NCT05435105
- Testing
- Virtual reality, Local cold-vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Virtual Reality
The Effect of Virtual Reality on Fear, Pain and Anxiety in Children Undergoing Circumcision
The aim of this study is to investigate the effect of virtual reality and cartoons and games on the anxiety, fear and post-procedural pain levels of children aged 7-12 years who will undergo circumcision.
- Trial name
- NCT06622369
- Testing
- Virtual Reality-Game group, Virtual Reality-Cartoon-video group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Multisensory Stimulation, Pain
The Effect of Multisensory Stimulation During Venipuncture on Pain, Anxiety, and Fear in Children
Venipuncture is one of the most common and distressing needle-related procedures for children, often causing significant pain, fear, and anxiety.
- Conditions
- Multisensory Stimulation, Pain, Venipuncture Pain, Fear
- Trial name
- NCT07769775
- Testing
- Multisensory stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi