Clinical trials: Anxious-Depressive
Depression, Unipolar, Anxiety Disorders
CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos
Latinos in the U.S. experience significant disparities in access to mental health services due to lack of health insurance, language barriers, low availability of bilingual providers, mental health stigma, and fear of…
- Conditions
- Depression, Unipolar, Anxiety Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT06139159
- Testing
- Outreach/navigator, Auxiliary to care, Stepped care and task shifting
- Where
- United States
- Volunteers
- 603 people
- Sponsor
- Drexel University
Depressive Disorders, Schizophrenia
Psychiatric Day Hospital Treatment
The aim of the study was to compare the effectiveness of acute psychiatric day care to conventional inpatient care within a cross-national multi-site randomised controlled trial.
- Conditions
- Depressive Disorders, Schizophrenia, Anxiety Disorders, Personality Disorders
- Trial name
- NCT00153959
- Testing
- acute psychiatric day care
- Where
- 5 sites in Czechia, Germany and 3 more
- Sponsor
- Technische Universität Dresden
Depressive Disorders, Anxiety Disorders
Stress, Anxiety, and Mood Group Therapy
The purpose of this study is to identify cognitive mechanisms that might facilitate treatment response for individuals experiencing depression and/or anxiety.
- Trial name
- NCT03855683
- Testing
- Unified Protocol for The Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Palo Alto University
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Mental Health Issue, Anxiety Disorder
Unified Protocol: Community Connections
The purpose of this study is to administer the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) and Adolescents (UP-A) to youth and participants' parents and to examine the efficacy and…
- Conditions
- Mental Health Issue, Anxiety Disorder, Depressive Disorder, Parenting
- Trial name
- NCT06038721
- Testing
- The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Children, The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Adolescents
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Miami
Depressive Disorder, Major, Anxiety Disorder
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
The study will investigate whether a nociceptin receptor antagonist will normalize neural and behavioral processes of approach/avoidance decision-making in unmedicated individuals with major depressive disorder (MDD) and anxiety…
- Trial name
- NCT05232032
- Testing
- Nociceptin Receptor Antagonist, Aversive stimuli
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Emotional Disorder, Anxiety Disorders
UP in Blended Format for Transdiagnostic Treatment of Emotional Disorders in the Spanish National Health System
The present randomized, controlled trial will compare the efficacy, cost-effectiveness, and implementation characteristics of a blended intervention based on the Unified Protocol (UP) for transdiagnostic treatment of emotional…
- Conditions
- Emotional Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT04304911
- Testing
- Blended intervention (UP-APP), Cognitive Behavioral Therapy (TAU)
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Depression, Anxiety
Depressive and Anxiety Disorders in Patients With Chronic Liver Diseases
The aim of this observational study is to learn about the prevalence of depressive and anxiety disorders among patients with chronic liver diseases
- Trial name
- NCT06113029
- Testing
- The Hamilton Rating Scale for Anxiety, The Beck Depression inventory, Rand SF-36 Questionnaire
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Post-Concussion Symptoms, Insomnia
Neurotechnology Following Traumatic Brain Injury
This two-part study seeks to improve symptoms such as pain and sleep problems after concussion, or mild traumatic brain injury (mTBI).
- Conditions
- Post-Concussion Symptoms, Insomnia, Pain, Chronic, Depressive Symptoms
- Trial name
- Cereset (NCT03649958)
- Testing
- HIRREM-SOP or Cereset, Cereset 2x
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Brain State Technologies, LLC
Depressive Disorders, Anxiety Disorders
APP: Mental Health Intervention Model for Healthcare Workers
This study, titled "APP: Mental Health Intervention Model for Healthcare Workers," aims to evaluate the effectiveness of a mobile app-based intervention to reduce emotional distress and symptoms of depression among healthcare…
- Conditions
- Depressive Disorders, Anxiety Disorders, Mental Health
- Trial name
- NCT06650449
- Testing
- Mobile App-Based Mental Health Support
- Where
- Ecuador
- Volunteers
- 168 people
- Sponsor
- Labora
Depressive Symptoms, Anxiety
The Impact of PM+For Moms Intervention on Improving Mother's Mental Health in Zambia (PM+FM)
CMHD are particularly prevalent among women, posing a major threat to their own and their children's wellbeing. Despite the high prevalence of CMHD and the existence of effective treatments, interventions supporting women living…
- Conditions
- Depressive Symptoms, Anxiety, Trauma, Psychological
- Trial name
- PM+FM (NCT05627206)
- Testing
- Problem Management + For Moms
- Where
- Zambia
- Volunteers
- 270 people
- Sponsor
- Swiss Tropical & Public Health Institute
Major Depressive Disorder, Anxiety
Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression
This is an add-on study to an existing multimodal neuroimaging study in MDD by investigating the acute effects of DLPFC tDCS on threat vigilance in 24-44 patients with MDD, as part of an open-label treatment intervention study.
- Trial name
- NCT03999736
- Testing
- transcranial direct current stimulation using a Soterix mini-CT device
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mclean Hospital
Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders
Ascertaining Diagnosis Classification With Elicited Speech
Cross-sectional observational study of the relationship between speech patterns and psychiatric symptoms and disorders.
- Conditions
- Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders, Depressive Disorder, Anxiety Disorders
- Trial name
- ACES (NCT05601063)
- Testing
- Winterlight Speech Assessment
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Depression, Dysthymic Disorder
Rumination Focus Cognitive Behavior Therapy
1. To investigate the efficacy and acceptability of a guided internet-delivered transdiagnostic intervention targeting repetitive negative thinking for individuals with elevated levels of depression and generalized anxiety…
- Conditions
- Depression, Dysthymic Disorder, Panic Disorder, Social Phobia
- Trial name
- iRFCBT (NCT03507114)
- Testing
- Rumination-Focused CBT (RFCBT)
- Where
- Romania
- Volunteers
- 90 people
- Sponsor
- West University of Timisoara
Cerebral Stroke
Links Between Depression, Anxiety, Coping and Quality of Life After a Stroke
Introduction and literature review With 130 000 cases per year in France in 2010, stroke is one of the most common neurological diseases, often leaving many disabling sequelae physical and cognitive levels (currently live 500 000…
- Trial name
- COPING (NCT02778334)
- Testing
- survey
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Depressive Disorder and Anxiety Disorders
A First Time in Human Study of GSK586529 in Healthy Volunteers
A single blind, randomized, placebo-controlled, crossover study in twenty four healthy male subjects. Subjects will be divided into two cohorts with alternate panel design.
- Trial name
- NCT00703547
- Testing
- GSK586529 capsules, GSK586529 tablets
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Major Depression, Generalized Anxiety
Common Factors Group Psychotherapy for General Mental Health Concerns
The current research will investigate the impact of general psychotherapy using common factors (i.e., techniques and communication skills that are common to all major forms of psychotherapy) to investigate whether mental health…
- Conditions
- Major Depression, Generalized Anxiety, Stress Disorder, Post Traumatic, Stress
- Trial name
- NCT06614842
- Testing
- Common Factors Group Psychotherapy
- Sponsor
- University of Alabama at Birmingham
Major Depressive Disorder, Generalized Anxiety Disorder
Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat
The primary objective of the study is to determine whether quetiapine extended-release in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo in treating depressive and anxiety symptoms in…
- Trial name
- NCT01971203
- Testing
- seroquel xr, CBT
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mental Health, PTSD
RESTORE in Patients Who Had COVID-19 and Close Others
There is considerable need for psychological intervention targeting stressor-related mental health symptoms related to COVID-19.
- Conditions
- Mental Health, PTSD, Anxiety, Depressive Symptoms
- Trial name
- NCT04958902
- Testing
- RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto