Clinical trials: Anxious-Depressive
Major Depression, Generalized Anxiety Disorder
Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months
The purpose of this study is to explore the changes in metabolic parameters in patients treated with escitalopram for six months for major depression, generalized anxiety disorder or panic disorder, with or without agoraphobia.
- Conditions
- Major Depression, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT00711737
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- Changi General Hospital
PostPartum Depression
Curio Digital Therapy for the Treatment of Post-partum Depression
Primary Objective: Evaluate the clinical effectiveness of the MamaLift Plus app compared to control (digital sham plus treatment as usual) for the management of PPD in the observed population for a period of 9 calendar weeks.
- Trial name
- SuMMER (NCT05958095)
- Testing
- MamaLift Plus
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Healthcare Innovation Technology Lab
Fibromyalgia
Supervised and Home Training in Fibromyalgia
The goal of this clinical trial is to evaluate the effectiveness of supervised multicomponent training (MCT) on physiological parameters, physical fitness, mental well-being, and quality of life in subjects with a history of…
- Trial name
- NCT06956456
- Testing
- Supervised Multicomponent Training Protocol, Non-Supervised Home-Based Multicomponent Training Protocol
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Bari Aldo Moro
Major Depressive Disorder (MDD), Anxiety Disorder
Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders
MAN-BIOPSY pursues the concrete research question whether novel biological and psycho-physiological clusters or categories can be defined to improve treatment and minimize side effects in psychiatry, based on a synopsis of…
- Trial name
- MAN-BIOPSY (NCT01477203)
- Testing
- Escitalopram
- Where
- Austria
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Depression and Quality of Life, Treatment Resistant Depression (TRD)
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
This observational study investigates the use of Esketamine Intranasal Spray in patients with Treatment-Resistant Depression in Real-World Settings.
- Conditions
- Depression and Quality of Life, Treatment Resistant Depression (TRD), Anhedonia, Apathy
- Trial name
- ESKPSY (NCT07146503)
- Testing
- Esketamine (Intranasal Spray)
- Where
- 5 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Riccardo Guglielmo
Subjective Memory Complaints, Anxiety
Eye-tracking Training for Older Adults
The goal of this clinical trial is to learn if a computerized eye-tracking training program can improve mental health and thinking skills in older adults.
- Trial name
- NCT07690709
- Testing
- Eye-Tracking Training
- Where
- 2 sites in Hong Kong
- Volunteers
- 78 people
- Sponsor
- Chinese University of Hong Kong
Depression, Anxiety
Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study
This study aims to investigate the association between the use different information sources to obtain information about the COVID-19 pandemic and symptoms of psychopathology (i.e., depression and anxiety).
- Trial name
- NCT04444336
- Testing
- Cross-sectional study examining the impact of information sources to obtain information about COVID-19 on depression and anxiety symptoms
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Subthreshold Depression, Depressive Symptoms
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression
Lycium barbarum, a traditional Chinese herbal medicine, is a commonly used herb in the traditional Chinese pharmacopoeia . Its main active ingredient, lycium barbarum polysaccharide (LBP), is reported to have neuroprotective…
- Conditions
- Subthreshold Depression, Depressive Symptoms, Anxious Symptoms
- Trial name
- NCT04032795
- Testing
- Lycium barbarum polysaccharide
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Guangzhou Psychiatric Hospital
Asthma, Chest Syndrome
Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma
Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually…
- Conditions
- Asthma, Chest Syndrome, Clinical Anxiety, Clinical Depression
- Trial name
- NCT03237221
- Testing
- Treat patient according to Global Initiative for Asthma (GINA) guideline
- Where
- 34 sites in China
- Volunteers
- 76 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Insulin Resistance, Low Birth Weight
Effects of 3 Months of Selective Serotonin Reuptake Inhibitor (SSRI)-Treatment on Metabolism and Hypothalamic-pituitary-adrenal (HPA)-Axis in Young Men Born With Low Birth Weight
Chronic stress has been proposed to be involved the development of western life-style diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Insulin Resistance, Low Birth Weight, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- LBW-SSRI (NCT00971815)
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression - Major Depressive Disorder, Anxiety
Singula Phase 0.1 Primary Care Pilot
This prospective, single-arm, observational pilot study evaluates a clinical decision support system developed by Singula Health for use in primary care.
- Trial name
- NCT07834684
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singula Health, Inc.
Insomnia, Insomnia Chronic
Assessment of Sleep Quality and Mental Health After Using Meditation
This is a randomized controlled trial that intends to verify the effectiveness of the daily practice of meditation before going to sleep for the improvement of sleep, stress, mental health and quality of life of people with sleep…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorder, Sleep Disorder
- Trial name
- NCT05812443
- Testing
- Shabad Kriya Meditation, Relaxing reading
- Where
- Brazil
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Depression
Examination of a Soy-Based Supplement for Major Depression
The purpose of this study is to find out if the soy-based dietary supplement Novasoy (Registered Trademark) is effective for the short-term treatment of clinical depression.
- Trial name
- NCT00042380
- Testing
- Novasoy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Parkinson's Disease (PD)
Full-Spectrum Cannabidiol Oil for Anxiety and Depressive Symptoms in Parkinson's Disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as bradykinesia, rigidity, and tremor.
- Trial name
- COOPERATE (NCT07651930)
- Testing
- Full-spectrum Cannabidiol (CBD) oil
- Where
- Poland
- Volunteers
- 27 people
- Sponsor
- Medical University of Warsaw
Stress, Anxiety
Effects of High Ventilation Breathwork With Retention (HVBR) on Health
The investigators are conducting a randomised-controlled trial comparing high ventilation breathwork with retention (HVBR) to a breathwork placebo (paced breathing at 15breaths/min with brief retentions).
- Conditions
- Stress, Anxiety, Depressive Symptoms, Mental Wellbeing
- Trial name
- NCT06064474
- Testing
- High ventilation breathwork with retention (HVBR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Depressive Symptoms, Anxiety Symptoms
Efficacy of a Mobile Phone App for Depression and Anxiety in College Students
The goal of this clinical trial is to evaluate the efficacy of a mobile phone application for the early intervention of depression and anxiety among young university students in Chile.
- Trial name
- VamosJuntxs (NCT06628830)
- Testing
- VamosJuntxs App, Web Conciencia Saludable
- Where
- Chile
- Volunteers
- 200 people
- Sponsor
- University of Chile
Obesity, Depressive Symptoms
The MIND-GUT Digital Pilot Intervention Study
This 12-week pilot study aims to evaluate the feasibility and effectiveness of a dietary intervention targeting diet, obesity, mental health, and the gut microbiome in promoting weight loss and enhancing mental health among obese…
- Conditions
- Obesity, Depressive Symptoms, Anxiety, Stress
- Trial name
- MINDGUT (NCT06374407)
- Testing
- Dietary intervention based on the MIND diet
- Where
- Sweden
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Skövde
Depression / Major Depressive Disorder, Anxiety Disorder (Panic Disorder or GAD)
Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and Anxiety
This pilot study evaluated the feasibility and preliminary outcomes of compassion-focused group therapy (CFT) for adults with depression and/or anxiety who continued to experience symptoms despite previous treatment.
- Trial name
- NCT07876453
- Testing
- Compassion-Focused Group Therapy (CFT)
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam