Clinical trials: Anxious-Depressive
Refractory Depression, Anxiety Disorders
Near-Infrared Laser Stimulation for Various Neurological Conditions
The study will evaluate the safety and feasibility of near infrared therapy as an intervention for patients with refractory depression, anxiety, neurodegenerative disease, and traumatic brain injury.
- Conditions
- Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases, Traumatic Brain Injury
- Trial name
- NCT04489082
- Testing
- Near Infrared Laser Stimulation
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Neurological Associates of West Los Angeles
Anxiety Disorders and Symptoms, Depressive Symptoms
Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On Modules
PROCARE is a preventive intervention that has shown its effectiveness in selective prevention to reduce young people's risk of developing emotional problems.
- Trial name
- PROCARE-I+ (NCT06350760)
- Testing
- Active control condition, PROCARE-I+ 8-session
- Where
- 3 sites in Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Major Depressive Disorder
A Study of JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms
The purpose of this study is to evaluate the efficacy and overall safety and tolerability of treatment with adjunctive JNJ-40411813 compared to placebo in patients with MDD with anxiety symptoms being treated with an…
- Trial name
- NCT01582815
- Testing
- JNJ-40411813
- Where
- 26 sites in Bulgaria, Hungary and 4 more
- Volunteers
- 121 people
- Sponsor
- Janssen Research & Development, LLC
Depressive Symptoms, Anxiety
A Trial of a Positive Psychology Intervention for Older Adults (RESET)
The heightened vulnerability to COVID-19 of African American older adults in Detroit, Michigan and other marginalized communities is linked to systemic racism experienced over the life course.
- Conditions
- Depressive Symptoms, Anxiety, Chronic Pain, Fatigue
- Trial name
- NCT05451589
- Testing
- RESET, Wellness Check Control
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- University of Michigan
Major Depressive Disorder, Generalized Anxiety Disorder
Cohort Study on Medical Students' Mental Health
The main objective of this study is to identify risk factors for depression among medical students by comparing them to students who completed their first year but did not enter the medical program (students not accepted into the…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation, Alcoholism
- Trial name
- OSMOSE (NCT07305701)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Depression - Major Depressive Disorder, Anxiety
Impact of Behavioral Activation on Depression and Quality of Life in Patients with Colon Cancer
The purpose of this randomized clinical trial is to study anxiety and depression symptoms at diagnosis in patients with colon cancer. Previous studies have shown that so-called.
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Colon Cancer
- Trial name
- BAdepCa (NCT06745700)
- Testing
- Brief Behavioural Activation, Care as usual
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Västmanland
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Depression, Postpartum, Anxiety
Implementation of a Psychoeducational Intervention in New Mothers
The goal of this clinical trial is to implement and examine the clinical effectiveness in a randomized study of the Catalan and Spanish versions of the culturally adapted "What Were We Thinking (WWWT)" psychoeducational…
- Trial name
- EQEP (NCT06512025)
- Testing
- WWWT psychoeducative intervention
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Alba Roca
Depression, Postpartum, Anxiety
Preventing Postpartum Depression With Intranasal Oxytocin
The purpose of this study is to test a new treatment for preventing childbirth-related mental illness in postpartum mothers. The treatment is aimed at enhancing maternal bonding, reducing postpartum depression (PPD) and anxiety…
- Trial name
- IN-OXT (NCT02505984)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, Anxiety Symptoms
Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong
The proposed study is a randomized controlled trial (RCT) that aims to examine the effectiveness of cognitive behavioural therapy in reducing depressive and anxiety symptoms for youths in Hong Kong.
- Trial name
- NCT05078424
- Testing
- Cognitive Behavioural Therapy
- Where
- Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vasomotor Symptoms, Urinary Incontinence
Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong
The goal of this randomized clinical trial is to learn if a nurse-led primary healthcare intervention can help improve health management in women adults aged 45 to 64, and to develop an evidence-based primary healthcare model for…
- Conditions
- Vasomotor Symptoms, Urinary Incontinence, Anxiety, Depression - Major Depressive Disorder
- Trial name
- JCDATAZONEWH (NCT06628388)
- Testing
- Nurse-Led Risk-Based 5As Primary Healthcare Model, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,728 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anxiety, Depressive Symptoms
Group Program vs Single-Session Depathologizing Intervention for Subthreshold Anxiety-Depression in Primary Care (Spain)
This study evaluated two psychological interventions for adults with mild to moderate subthreshold anxious-depressive symptoms in primary care in Spain.
- Conditions
- Anxiety, Depressive Symptoms, Anxiety Symptoms, Subthreshold Depression
- Trial name
- NCT07363915
- Testing
- PADAP transdiagnostic CBT-based group program, Active Single-Session Depathologizing Intervention (SSDI)
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- University of Alcala
Schizophrenia, Schizoaffective Disorder
Abilify Therapy for Reducing Comorbid Substance Abuse
It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: Reduction in the amount of alcohol and/or drugs used as measured by the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00208169
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Depressive Disorder, Major, Anxiety Disorders
Evaluate the Quality of Life and Treatment of Anxiety Symptoms of Buspirone in Patients With Depression Disorders(BASIS)
Approximately 20 sites in Korea including the Catholic University of Korea, Yeouido St. Mary's Hospital. Patients with Depressive disorders taking a selective serotonin reuptake inhibitor (SSRI) antidepressant or Serotonin and…
- Trial name
- BASIS (NCT04770454)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Generalized Anxiety Disorder, Major Depressive Disorder
Improving Access to the Treatment of Anxiety and Depression Among Young Adults
Anxiety and depression represent the most common mental health problems. Unfortunately, only a minority of people in need will seek or access traditional mental health services.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03156556
- Testing
- Mood Mechanic Course
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Universite de Moncton
Diabetes Mellitus, Type 2
Intervention for Reducing Psychiatric Symptoms and Metabolic Variables in Patients With Diabetes Mellitus (DM)
The purpose of this study is apply a Brief Intervention (PST) in Diabetic and Obesity patient in primary care of Mexico City to improve their depressive and anxious symptoms and stabilization of metabolic variables.
- Trial name
- DM (NCT02889172)
- Testing
- Problem Solving Therapy
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Depression, Anxiety Disorders
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Depression and anxiety are common mental health problems. There are effective treatments for depression and anxiety and one of these is talking therapies using cognitive behaviour therapy (CBT).
- Conditions
- Depression, Anxiety Disorders, Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- D-IAPT (NCT03188575)
- Testing
- SilverCloud Internet-delivered Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- Silver Cloud Health
Schizophrenia, Treatment Resistant Depression (TRD)
Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment
The disruption of immune system is a key candidate in the pathogenesis of psychiatric disorders, especially those resistant to traditional treatments.
- Conditions
- Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia
- Trial name
- BIO-INM (NCT07741981)
- Testing
- Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier St Anne
Anorexia Nervosa (DSM-IV Revised Criteria)
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
The goal of this clinical trial is to evaluate the safety and initial clinical effectiveness of MRI-guided focused ultrasound (MRgFUS) thermal ablation (capsulotomy) in patients with treatment-refractory anorexia nervosa (AN) and…
- Trial name
- NCT07113665
- Testing
- ExAblate Neuro 4000
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression, Anxiety, Quality of Life
Investigating Whether Digital Acceptance Commitment Therapy Can Improve Mental Health for Hong Kong Cancer Patients Suffering From Depressive and Anxiety Symptoms.
The goal of this clinical trial is to validate the use of digital Acceptance and Commitment Therapy (Digi-ACT) in Hong Kong curative cancer patients with depressive and anxiety symptoms.
- Conditions
- Depression, Anxiety, Quality of Life, Cancer
- Trial name
- Digi-ACT (NCT05583851)
- Testing
- Acceptance and Commitment Therapy, Psychoeducation Active Control
- Volunteers
- 50 people
- Sponsor
- Hollo