Clinical trials: Anxious-Depressive
Anxiety Disorder, Depressive Disorder
Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children
American Indians (AI) are at greater risk for anxiety and depression early in life. This is concerning given the potential negative effects of these conditions across the lifespan (substance use, suicide).
- Trial name
- NCT05371665
- Testing
- Culturally Adapted Cognitive-Behavioral Prevention and Early Intervention (PEI) Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Montana State University
Substance Use, Conduct Disorder
A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2)
The goal of this project is to empirically refine and improve a comprehensive family-centered prevention strategy for reducing and preventing adolescent substance use and other problem behaviors.
- Conditions
- Substance Use, Conduct Disorder, Depression, Anxiety
- Trial name
- PAL-2 (NCT01490307)
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 593 people
- Sponsor
- University of Oregon
Major Depression, Generalized Anxiety Disorder
Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines
The hypothesis of this study is that symptoms of anxiety, depression and insomnia; and indices of psychosocial function will all improve, while BZ use will decrease significantly during a twelve-week trial period of substituting…
- Trial name
- NCT01244711
- Testing
- quetiapine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Depressive Disorder, Depression
The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation and Oxidative Stress Parameters and Faecal Microbiota in Patients With Depression Depending on Metabolic Syndrome Comorbidity
The trial will be a four-arm, parallel group, prospective, randomized, double-blind, controlled design that will include 200 participants and will last 20 weeks.
- Conditions
- Depressive Disorder, Depression, Anxiety, Stress
- Trial name
- PRO-DEMET (NCT04756544)
- Testing
- Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-175
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Lodz
Depressive Disorder, Anxiety Disorder
Collaborative and Stepped Care in Mental Health (COMET)
The aims of COMET are the implementation and evaluation of effectiveness and cost-effectiveness as well as processes of a collaborative and stepped care model for depressive, anxiety, somatoform and/or alcohol abuse disorders…
- Conditions
- Depressive Disorder, Anxiety Disorder, Somatoform Disorder, Alcohol Use Disorder
- Trial name
- COMET (NCT03226743)
- Testing
- collaborative and stepped care model
- Where
- Germany
- Volunteers
- 615 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depressive Symptoms, Anxiety Disorders and Symptoms
Evaluating a Virtual Mentoring Program Plus Mental Health Videos for Teens
This clinical trial evaluates Appa Health, a mental health smartphone and computer app for teenagers. Appa is built from two components.
- Trial name
- NCT06138730
- Testing
- Appa Complete, Appa Lite
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Appa Health
Depressive Symptoms, Anxiety
Expressive Writing on Minority Stressors Among Sexual Minority Veterans
Sexual minority stressors (e.g., sexual minority identity-based discrimination) contribute to greater risk for and severity of depression, anxiety, substance use disorders and suicide among sexual minority Veterans.
- Trial name
- EWMS (NCT05897021)
- Testing
- Expressive Writing on Minority Stressors, Neutral Writing
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- VA Office of Research and Development
Major Depression
High-Frequency vs. Theta-Burst TMS for Depression
The goal of this clinical trial was to learn if two different types of repetitive transcranial magnetic stimulation (rTMS) could help treat depression and anxiety in adults with major depressive disorder.
- Trial name
- NCT07181226
- Testing
- High-frequency repetitive transcranial magnetic stimulation, Intermittent Theta Burst Stimulation
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Krajská zdravotní, a.s. - Nemocnice Most, o.z.
Anxiety State
Music Listening to Lower Anxiety During ECT Treatment.
The purpose of this study is to assess whether music listening is helpful in lowering anxiety in patients about to start their ECT treatment.
- Trial name
- MIECT (NCT04706728)
- Testing
- Listening to playlists with music prior to-, during and after the ECT procedure, Listening to playlists with sound from nature (rain, waves) prior to-, during and after the ECT procedure
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Aalborg University
Anxiety, Depression / Major Depressive Disorder
The Effectiveness of a One-stop Electronic Clinic for Psychological Service (eClinic) in Hong Kong
With an increasing need for effective and accessible mental health services, telepsychology can be one promising solution to narrowing the gap between demand and supply.
- Conditions
- Anxiety, Depression / Major Depressive Disorder, Common Mental Disorder
- Trial name
- NCT07597967
- Testing
- Internet-based Unified Protocol (UP) Intervention
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Healthy, Posttraumatic Stress Disorder
Brain Function in Mentally Ill Adolescents
The purpose of this study is to use brain imaging technology to examine the brain activity of adolescents with post-traumatic stress disorder (PTSD) and/or major depressive disorder (MDD) before and after treatment.
- Conditions
- Healthy, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT00025857
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Institute of Mental Health (NIMH)
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Acquired Brain Injury, Depressive Symptoms
A Single-case Design to Investigate a Compensatory Brain Game Supporting Goal Management Training Intervention in a Psychiatric Brain Injury Population
The main cognitive complaint in brain-injured patients is often the everyday disorganization caused by Executive Function (EF) deficits. EF deficits are often seen in patients with psychiatric disorders i.e.
- Conditions
- Acquired Brain Injury, Depressive Symptoms, Anxiety, Executive Dysfunction
- Trial name
- NCT06352346
- Testing
- Compensatory brain game supporting Goal Management Training intervention
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- ProPersona
Depressive Symptoms, Anxiety
Evaluating an Online Wellness Intervention for Greek Adolescents
The investigators are evaluating the effects of an online single-session mental health intervention (the Common Elements Toolbox; COMET).
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT04815681
- Testing
- Common Elements Toolbox, Active Control
- Where
- 2 sites in United States, Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Depressive Disorders
Transdiagnostic Group Treatments for Patients With Common Mental Disorders in Primary Health Care
The purpose of this study is to compare the effects of CBT and MMI on the quality of life and relief of psychological symptoms of patients with common mental disorders or problems attending primary health care centre.
- Conditions
- Anxiety Disorders, Depressive Disorders, Stress Disorders
- Trial name
- NCT01565213
- Testing
- CBT, MMI, CAU
- Where
- Sweden
- Volunteers
- 245 people
- Sponsor
- Karolinska Institutet
Major Depression, Anxiety Disorder
Tackling Depression and Anxiety: A Working Memory Intervention
Anxiety and depression are both associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02119923
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Erasmus Medical Center
Panic Disorder, Major Depressive Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major Depression
This study will evaluate the efficacy of 1-Hz rTMS applied to the right Dorsolateral Prefrontal Cortex (DLPFC) in patients with Panic Disorder (PD) and comorbid Major Depressive Disorder (MDD) who have not fully responded to…
- Trial name
- rTMS (NCT00521352)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute
Obsessive Compulsive Disorder (OCD)
Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial
This randomized controlled trial examines the effects of a mobile-based gamified combined cognitive bias modification (CBM-C) intervention on obsessive-compulsive symptoms, obsessive beliefs, attentional and interpretation…
- Trial name
- NCT06941155
- Testing
- Gamified-Combined Cognitive Bias Modification, Standard Combined Cognitive Bias Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
PTSD, Autism Spectrum Disorder High-Functioning
Psychiatric Orders in Psychoanalytic Treatment of ASD
Autism Spectrum Disorder (ASD) is often accompanied by a variety of other symptoms, such as bipolar disorder, Attention Deficit Hyperactivity Disorder (ADHD), Social Anxiety Disorder (SAD), Avoidant Personality Disorder (AvPD)…
- Conditions
- PTSD, Autism Spectrum Disorder High-Functioning, OCD, Agoraphobia With Panic Attacks
- Trial name
- NCT05930912
- Testing
- Psychoanalysis, sertraline 50mg, Duloxetine 20 MG
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Yang I. Pachankis, PhD
Depressive Disorder, Generalized Anxiety Disorder
Qualitative Study of Student Financial Insecurity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation
- Trial name
- QUALIPEPSY (NCT07719816)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris