Clinical trials: Aortic Aneurysm, Abdominal, open to volunteers
Aortic Aneurysm, Aortic Aneurysm Abdominal
Evaluation of the iCover Stent as a Bridging Stent in Fenestrated Endovascular Aneurysm Repair (fEVAR) for Complex Aortic Aneurysms.
ReiCo is a French retrospective, multicenter, single-arm study focused on assessing the safety and clinical performance of the iCover balloon-expandable covered stent (iVascular) when implanted as a bridging stent during fEVAR…
- Trial name
- ReiCo (NCT07742254)
- Where
- 3 sites in France
- Volunteers
- 154 people
- Sponsor
- iVascular S.L.U.
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
- Trial name
- ADVANCE (NCT05378347)
- Testing
- Medtronic Endurant II or Endurant IIs Stent Graft System, Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
- Where
- 68 sites in United States, Finland and 10 more
- Volunteers
- 600 people
- Sponsor
- Medtronic Cardiovascular
Postoperative Pain, Abdominal Aortic Aneurysm
Pain Control After Aortic EndoaneurYsmEctomy (POPEYE)
Open abdominal aortic aneurysm repair (OR-AAA) is an operation associated with high morbidity, and has 30-day mortality rates of between 4 and 14%. Post-operative pain management represents a primary anesthetic focus.
- Trial name
- POPEYE (NCT06244732)
- Testing
- Postoperative pain control
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
Endovascular Repair of Infrarenal Abdominal Aortic Aneurysm Using Endovascular Stent Graft
Post-market European & Asian Registry to Evaluate the Minos™ Stent-Graft and Delivery System in Abdominal Aortic Aneurysm Treatment
The Minos™ Abdominal Aortic Stent-Graft and Delivery System is a medical device designed to treat abdominal aortic aneurysms using a minimally invasive procedure.
- Trial name
- PEARL (NCT07674173)
- Testing
- Implantation with Minos Stent graft
- Where
- 16 sites in China, Germany and 4 more
- Volunteers
- 200 people
- Sponsor
- Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd
Elective Surgical Procedures, Postoperative Pain
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Open Abdominal Aortic Aneurysm (AAA) repair is a high-risk surgical procedure accompanied by intense endocrine and metabolic responses to surgical stress, with subsequent activation of the inflammatory cascade, cytokine and…
- Conditions
- Elective Surgical Procedures, Postoperative Pain, Anesthesia, Opioid Use
- Trial name
- NCT04894864
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Crete
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
European Aortic Data Collection Project
The purpose of this study is to evaluate the safety and performance of Cook's various Custom-Made Stent-graft Devices (CMD) used for endovascular treatment of the aorta and related diseases by collecting information on the…
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Chronic Aortic Dissection
- Trial name
- EADC (NCT05896397)
- Testing
- Endovascular Aortic Treatments
- Where
- 18 sites in Denmark, France and 4 more
- Volunteers
- 600 people
- Sponsor
- Cook Research Incorporated
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
AAA - Abdominal Aortic Aneurysm, Aorta Aneurysm
Nectero EAST System Retreatment Study
This is an exploratory pilot study to evaluate the safety and clinical utility of retreatment with an investigational combination product called the Nectero EAST System to treat Abdominal Aortic Aneurysms or AAA.
- Conditions
- AAA - Abdominal Aortic Aneurysm, Aorta Aneurysm, Dilation Aorta
- Trial name
- NCT07505082
- Testing
- Nectero EAST System
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 10 people
- Sponsor
- Nectero Medical, Inc.
Aortic Aneurysm, Abdominal
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated…
- Trial name
- SOCRATES (NCT04503395)
- Testing
- ESAR treatment: Endograft + Heli-FX Endoanchor, FEVAR treatment : Fenestrated endograft
- Where
- 33 sites in United States, Austria and 8 more
- Volunteers
- 204 people
- Sponsor
- FCRE (Foundation for Cardiovascular Research and Education)
Abdominal Aortic Aneurysm
Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
This research study is being conducted to test how an imaging drug called 64Cu-DOTA-ECL1i can be used to image an abdominal aortic aneurysm.
- Trial name
- NCT07548099
- Testing
- 64Cu-DOTA-ECL1i
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Juxtarenal Abdominal Aortic Aneurysm
University of Utah PS-IDE: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
The purpose of this study is to assess the effects of a physician-modified endovascular graft (PMEG) for juxtarenal aortic aneurysms by collecting data on its performance.
- Trial name
- NCT07065760
- Testing
- Endovascular Aneurysm Repair with Physician Modified Endograft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cali Johnson
Aortic Aneurysm, Abdominal, Thoracic Aneurysm
Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
The purpose of this study is to assess the clinical outcomes and radiation of the use of off-the-shelf and custom-made devices (CMDs) for the endovascular repair of juxtarenal, suprarenal, thoracoabdominal and arch aortic…
- Trial name
- NCT02266719
- Testing
- Fenestrated CMD, Type I - III TAAA, Arch cohort
- Where
- 4 sites in United States
- Volunteers
- 750 people
- Sponsor
- Carlos Timaran
Aortic Aneurysm, Abdominal
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
The HERCULES trial is a Randomized controlled clinical trial designed to prospectively compare endosuture aneurysm repair (ESAR) to standard endovascular aneurysm repair (EVAR) clinical outcomes in treatment of infrarenal…
- Trial name
- HERCULES (NCT05484115)
- Testing
- endovascular aneurysm repair (EVAR) using the Endurant II/IIs stent graft system, endosuture aneurysm repair (ESAR) using Heli-FX EndoAnchor system
- Where
- 36 sites in United States, France and 6 more
- Volunteers
- 300 people
- Sponsor
- Rijnstate Hospital
Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations
Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair
This study will evaluate the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.
- Conditions
- Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation
- Trial name
- CoFA-TAAA (NCT06432387)
- Testing
- Patients undergoing complex thoraco-abdominal aortic aneurysm repair
- Where
- 2 sites in Greece
- Volunteers
- 58 people
- Sponsor
- University of Thessaly
Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm
Physician Modified Endograft For Complex Aortic Aneurysm Repair
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk…
- Conditions
- Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT05339061
- Testing
- Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Aortic Aneurysm, Aortic Dissection
Cardiovascular Health Improvement Project
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure
- Trial name
- CHIP (NCT02306200)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Abdominal Aortic Aneurysm
Mechanistic Clinical Trial of PCSK9 Inhibition for AAA
The goal of this mechanistic clinical trial is to assess whether lowering the low-density lipoprotein cholesterol (LDL-C) levels in the blood with the injections of the medication evolocumab will have any effect on the tissue or…
- Trial name
- NCT06081153
- Testing
- Evolocumab
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Pennsylvania
Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm
Evaluation of Clinical Efficacy and Safety of Aortal Stent-Graft Created Using 3D Printing Technology
the comparison of physician-modified stent-graft created in 3D models versus custom-made devices in the treatment of complex abdominal aortic aneurysm
- Conditions
- Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm, Pararenal Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06969729
- Testing
- Physician-Modified Fenestrated Stent-Graft (3D-Printed Template-Guided)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Samodzielny Publiczny Szpital Kliniczny nr 2 PUM
Aortic Aneurysm, Abdominal, Ascending Aorta Aneurysm
Evaluation of Visceral Function Following Endovascular Aortic Aneurysm Repair Using Branched Stent- Grafts
The purpose of this study is to evaluate visceral function, after endovascular repair of thoracoabdominal aneurysms or ascending/aortic arch aneurysms.
- Conditions
- Aortic Aneurysm, Abdominal, Ascending Aorta Aneurysm, Aortic Arch Aneurysm
- Trial name
- NCT01654133
- Testing
- Endovascular repair of thoracoabdominal aortic aneurysm (TAAA) using branched stent graft, Endovascular repair of ascending/arch aortic aneurysm using branched stent graft
- Where
- United States
- Volunteers
- 770 people
- Sponsor
- University of North Carolina, Chapel Hill
Complex Abdominal Aortic Aneurysms
Clinical Performance and Safety Assessment of the Use of iCover Balloon Expandable Covered Stent (iVascular) Implanted as Bridging Stent in FEVAR (Fenestrated Endovascular Aortic Repair) for the Treatment of Complex Abdominal Aortic Aneurysms
fenCo is a European multicentre, prospective study to evaluate the use of the iCover covered stents as bridging stents for reno-visceral target vessel during fEVAR for the treatment of complex abdominal aortic aneurysms.
- Trial name
- fenCo (NCT07529275)
- Testing
- iCover balloon-expandable covered peripheral stent system as bridging stent
- Where
- 24 sites in Belgium, France and 3 more
- Volunteers
- 165 people
- Sponsor
- iVascular S.L.U.