Clinical trials: Aortic Rupture
Rupture, Aortic, Aneurysm, Abdominal Aortic
Greek Study for Endovascular Repair of Ruptured Abdominal Aortic Aneuryms
This will be a non-randomized, prospective, observational multi-center research study. Its purpose will be to assess the mortality and outcome of EVAR in patients with rAAA.
- Conditions
- Rupture, Aortic, Aneurysm, Abdominal Aortic, Aneurysm, Ruptured
- Trial name
- GRAND (NCT04471181)
- Testing
- Endovascular repair of ruptured abdominal aortic aneurysm (EVAR) with Medtronic Endurant
- Where
- Greece
- Volunteers
- 157 people
- Sponsor
- Kostantinos Papazoglou
Abdominal Aortic Aneurysm Without Rupture
Non-invasive Aortic Aneurysm Tissue Characterization Using Wall Viscoelasticity
Abdominal aortic aneurysm (AAA) is an abnormal dilatation of the aorta in the abdomen due to a wall weakening caused by atherosclerosis.
- Trial name
- AAA multiphase (NCT04150653)
- Testing
- Multiphase scan CT, non-invasive vascular ultrasound elastography by ultrasound (NIVE)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
GORE® TAG® Thoracic Endoprosthesis French Mandatory Registry
This is a French Registry mandated by the French National Health Authority assessing long-term (5-years) safety of the GORE® TAG® Thoracic Endoprosthesis treating diseases of the thoracic aorta.
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Aortic Diseases, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT02266342
- Testing
- GORE® TAG® Thoracic Endoprostheses
- Where
- France
- Volunteers
- 154 people
- Sponsor
- W.L.Gore & Associates
Aorta Aneurysm, Aorta Dissection
Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)
Multicentre prospective registry including consecutive patients undergoing Percutaneous Endovascular Aneurysm Repair (PEVAR), Percutaneous Endovascular Thoracic Aneurysm Repair (PTEVAR) or Transcatheter Aortic Valve Implantation…
- Conditions
- Aorta Aneurysm, Aorta Dissection, Aorta Stenosis, Aortic Coarctation
- Trial name
- SPAIN (NCT04307888)
- Testing
- Perclose Proglide (Abbott)
- Volunteers
- 600 people
- Sponsor
- Sociedad Espanola de Angiologia y Cirugia Vascular
Aortic Rupture
In Vivo Evaluation of Growth and Risk of Rupture of Dilated Ascending Aorta Using 4D Cardiac Magnetic Resonance
Ascending aorta aneurysmal disease is common and can be complicated by dissection or rupture. There is substantial variation in individual aneurysm progression: established risk factors for an accelerated aneurysm growth rate…
- Trial name
- NCT03172390
- Testing
- 4D Cardiac Magnetic Resonance
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm Without Rupture
Shockwave™Peripheral Intravascular Lithotripsy Balloon for Advanced Endovascular Aortic Repair
Shockwave TEVAR is a nonrandomized, prospective, international, multi-center, PMCF, obervational study. The aim of this study is to evaluate the outcomes of the Shockwave™ Peripheral Intravascular Lithotripsy Balloon (Shockwave…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm Without Rupture, Thoracic Aortic Aneurysm Without Rupture
- Trial name
- TEVAR (NCT06332911)
- Testing
- Shockwave™ Peripheral Intravascular Lithotripsy Balloon M5+
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 30 people
- Sponsor
- Rede Optimus Hospitalar SA
Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured
Prospective Aortic Biobank of POP-STAR
The overall objective of the POP-STAR project is individualized surveillance for patients diagnosed with abdominal aortic aneurysms by means of more precise, patient-specific AAA growth prediction.
- Conditions
- Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured, Aortic Aneurysm, Aneurysm Abdominal
- Trial name
- NCT04269447
- Testing
- Structured imaging follow-up
- Where
- 2 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Aortic Aneurysm
Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms
It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.
- Trial name
- NCT06365138
- Testing
- Bahaviour at the time of an aortic aneurysm rupture
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Augsburg
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
Elective Treatment Rates and Surgical Non-eligibility Among Men and Women With Intact Abdominal Aortic Aneurysms
The overall aim is to determine the frequency by which women and men with intact abdominal aortic aneurysms (AAA) are treated with elective surgery at three vascular outpatient clinics in Europe, and to investigate whether the…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Aneurysm, Aortic Aneurysm
- Trial name
- NCT05346289
- Testing
- Elective surgery for intact AAA
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Thoracic Aorta
Aortic Elongation and Dissection
Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.
- Trial name
- NCT02722889
- Where
- Netherlands
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Abdominal Aortic Aneurysm Without Rupture
EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study
Prospective, multicenter, single arm study with consecutive, eligible subject enrollment at each site. All subjects will undergo the Endovascular Aneurysm repair procedure with the Nellix System.
- Trial name
- EVAS2 (NCT03298477)
- Testing
- Nellix® System
- Where
- 27 sites in United States
- Volunteers
- 98 people
- Sponsor
- Endologix
Thoracic Aortic Aneurysm Without Rupture, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Adolescents With Thoracic Aortic Aneurysm
The objective of this prospective cohort study is to determine the prevalence of obstructive sleep apnoea (OSA) in patients with and without thoracic aortic aneurysm.
- Trial name
- OSA in TAA (NCT03400319)
- Where
- Switzerland
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Juxta Renal Abdominal Aortic Aneurysm Without Rupture, Complex Aortic Aneurysms
Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms
The primary objective of the clinical investigation "Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms" is to assess the use of the Physician-Modified…
- Conditions
- Juxta Renal Abdominal Aortic Aneurysm Without Rupture, Complex Aortic Aneurysms, Aortic Aneurysm
- Trial name
- NCT06834607
- Testing
- Physician Modified Aortic Endograft repair for complex aortic aneurysm
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Akhilesh Jain
Abdominal Aortic Aneurysm Without Rupture
New MRI Techniques for Diagnosis and Treatment of Patients With Abdominal Aortic Aneurysms
An abdominal aortic aneurysm (AAA) is a pathological dilatation of the aorta in the belly which can rupture leading to bleeding within the belly. To prevent rupture elective surgery can be performed.
- Trial name
- MARVY (NCT05976711)
- Testing
- Magnetic resonance imaging (with PROUD software)
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Marfan Syndrome, FBN1 Mutation
Genome-wide Epistasis for Cardiovascular Severity in Marfan Study
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder with pleiotropic manifestations in the ocular, skeletal and cardiovascular systems.
- Trial name
- GEMS (NCT06257004)
- Testing
- Saliva collection (screening of all participants), Bloodsampling
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Aortopathies, Thoracic Aortic Aneurysm
Pathogenetic Basis of Aortopathy and Aortic Valve Disease
The main purpose of this study is to define the complex genetic and pathogenic basis of thoracic aortic aneurysm (TAA) and other forms of aortopathy and/or aortic valve disease by identifying novel disease-causing genes and by…
- Conditions
- Aortopathies, Thoracic Aortic Aneurysm, Aortic Valve Disease, Thoracic Aortic Disease
- Trial name
- TAA (NCT03440697)
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Yale University
Abdominal Aortic Aneurysm (AAA)
Predictors of AAA Expansion and/or Rupture
Eligible subjects in this study will have either a known abdominal aortic aneurysm (AAA) or because they do not have an AAA (control group).
- Trial name
- NCT03231397
- Testing
- Assess AAA rupture risk by PET-CTA scans, 18F-fludeoxyglucose (FDG), 11C-PBR28
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Aortic Dissection Aneurysm, Aortic Dissection Rupture
Effects of Precise Education on Postoperative Discomfort Symptoms in Patients With Aortic Disease Undergoing Endovascular Intervention: a Single-center Randomized Controlled Study
The incidence and severity of post-procedural discomfort were evaluated in patients undergoing endovascular repair for aortic dissection across six symptom-related dimensions: immobilization-related issues, puncture site…
- Conditions
- Aortic Dissection Aneurysm, Aortic Dissection Rupture, Aortic Dissection Involving the Descending Thoracic Aorta
- Trial name
- NCT07362901
- Testing
- postoperative precise education
- Where
- China
- Volunteers
- 132 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Abdominal Aortic Aneurysm Without Rupture
Secondary Intervention and Surveillance After EVAR
This is a retrospective cohort study of consecutive patients submitted to elective EVAR, between February/2009 and May/2019 in a single institution.
- Trial name
- NCT05335642
- Testing
- EVAR
- Where
- Portugal
- Volunteers
- 214 people
- Sponsor
- Hospital Sao Joao
Abdominal Injury, Pelvic Fracture
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of "occult" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the…
- Conditions
- Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury
- Trial name
- NEXUS AP CT (NCT04937868)
- Testing
- There are no interventions associated with this study
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- University of California, Los Angeles