Clinical trials: Aphakia
Cataract Unilateral, Aphakia
Prospective Clinical Trial to Evaluate the Safety and Effectiveness of the IOL
To establish the safety and effectiveness of the CT LUCIA 611P posterior chamber intraocular lens for the correction of aphakia following extracapsular cataract extraction via phacoemulsification in adult patients.
- Trial name
- NCT03451786
- Testing
- IOL
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Estelle Poineau
Aphakia, Cataract
RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study
The primary objective of this study is to conduct a post-approval study which compares the LAL to a monofocal control IOL for safety outcomes.
- Trial name
- NCT05202808
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 14 sites in United States
- Volunteers
- 500 people
- Sponsor
- RxSight, Inc.
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Safety and Effectiveness of the Akreos Toric Intraocular Lens.
The purpose of this study is to evaluate the safety and effectiveness of the Akreos Toric IOL following cataract surgery.
- Trial name
- NCT00825513
- Testing
- Akreos Toric IOL, Akreos Advanced Optics Aspheric Intraocular Lens (Akreos AO)
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Cataract
Comparison of the Hoya Surgical Optics (HSO) iSert 251 Posterior Chamber Aspheric Aphakic Intraocular Lens to Historical / Literature Controls.
The purpose of this multi-center clinical trail is to determine the safety and efficacy of the iSert 251 for the correction of aphakia.
- Trial name
- NCT01292629
- Testing
- iSert 251 intraocular lens
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Hoya Surgical Optics, Inc.
Aphakia, Presbyopia
Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL
The purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).
- Trial name
- NCT04330001
- Testing
- Alcon Fluid Accommodating Intraocular Lens, Top Con Autorefractor
- Where
- 2 sites in El Salvador, Panama
- Volunteers
- 99 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
The objectives of the clinical investigation are to determine the safety and performance of the RayOne EMV Toric (Model RAO210T) following unilateral implantation and approximately 6 months (120 to 180 days) of post-operative…
- Trial name
- NCT05985304
- Testing
- RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Rayner Intraocular Lenses Limited
Aphakia, Presbyopia
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs
This is a prospective, multicenter, post-approval active surveillance study. The purpose of this study is to report the rate of post-surgical intraocular inflammation (based upon a specified case definition) reported within a…
- Conditions
- Aphakia, Presbyopia, Astigmatism
- Trial name
- NCT03733730
- Testing
- ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 2,449 people
- Sponsor
- Alcon Research
Aphakia
Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and Crystalens™ AO Aberration-free Accommodating intraocular lens (IOLs) 6 months after post cataract surgery.
- Trial name
- NCT01061281
- Testing
- Tecnis MF IOL, Crystalens AO IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Cataract, Aphakia
Co-Axial Micro-Incision Versus Co-Axial Small Incision Cataract Surgery Using the Stellaris Enhancement System
The objective of this study is to test the hypothesis that the time to reach a stable refraction is significantly shorter in eyes operated with the 1.8 mm coaxial microincision compared to eyes operated with the 2.75 mm standard…
- Trial name
- NCT01261975
- Testing
- Coaxial Micro-Incision Cataract Surgery, Coaxial Small Incision Cataract Surgery
- Volunteers
- 36 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Astigmatism
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
The purpose of this Post-Market Clinical Follow-up study is to describe the long-term safety and performance of the Clareon Vivity and Vivity Toric and Clareon PanOptix and PanOptix Toric IOLs.
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT05796453
- Testing
- Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 470 people
- Sponsor
- Alcon Research
Cataract, Aphakic Eye
Comparative Study of the Tomey OA-2000, Tomey CASIA2, and the LenStar LS900
This is a prospective comparative study that will be conducted at one clinical site in the United States, in which subjects who sign an informed consent form and fulfil all inclusion and exclusion criteria, will have OCT scans…
- Conditions
- Cataract, Aphakic Eye, Pseudophakia
- Trial name
- NCT06065072
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Cataract
EYEFILL® C. -US Viscoelastic Clinical Investigation
The purpose of this multicenter, prospective, randomized clinical study is to determine the safety and effectiveness of the EYEFILL® C.-US Viscoelastic in patients undergoing cataract extraction and intraocular lens (IOL)…
- Trial name
- NCT02024711
- Testing
- EYEFILL® C.-US Viscoelastic, Healon® Viscoelastic (CONTROL)
- Where
- 8 sites in United States
- Volunteers
- 262 people
- Sponsor
- Bausch Health Americas, Inc.
Aphakia, Cataract
One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of this study is to evaluate the safety and effectiveness of the enVista® One-Piece Hydrophobic Acrylic intraocular lens (IOL), following primary implantation for the visual correction of aphakia in adults 18 years…
- Trial name
- NCT01230060
- Testing
- enVista
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
- Trial name
- NCT01547429
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 18 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Cataract, Aphakia
Post-Market Clinical Investigation of the Clareon® IOL
The primary purpose of this study is to evaluate the long-term (3 years) visual acuity and adverse event outcomes for the Clareon® Intraocular Lens (IOL).
- Trial name
- NCT03316885
- Testing
- Clareon® IOL, Cataract Surgery
- Where
- 19 sites in Australia, France and 5 more
- Volunteers
- 245 people
- Sponsor
- Alcon Research
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Cataract Senile
AT ELANA 841P Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal
The goal of this clinical trial is to demonstrate the safety and effectiveness of the full visual range AT ELANA 841P IOL when used to treat adult patients having cataract surgery.
- Trial name
- NCT06264232
- Testing
- Cataract Surgery
- Where
- 14 sites in United States
- Volunteers
- 284 people
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract
A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery
To evaluate safety and efficacy of MD-15 intraocular lens implanted into the aphakic eyes
- Trial name
- NCT02888210
- Testing
- MD-15 Intraocular Lens
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.