Clinical trials: Aphasia Rehabilitation
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Aphasia, Apraxia of Speech
MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish Healthcare
Positive outcomes have been shown following intensive treatment of speech and/or language impairment post stroke, but how to design intensive treatment programs to achieve optimal recovery and neuroplasticity changes needs to be…
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- MIRAA (NCT04957225)
- Testing
- MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of speech)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Aphasia, Spatial Neglect
Prism Adaptation in Left Brain Stroke
Of the 15,000 Veterans who are hospitalized for stroke each year more than half experience spatial and motor impairments and pain.
- Conditions
- Aphasia, Spatial Neglect, Stroke
- Trial name
- NCT04387162
- Testing
- Prism Adaptation Treatment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- VA Office of Research and Development
Aphasia, Post-stroke
Transcranial Direct Current Stimulation to Enhance Training Effectiveness in Chronic Post-Stroke Aphasia
The aim of the study is to investigate whether intensive speech-language therapy (SLT) combined with anodal transcranial direct current stimulation (tDCS) leads to better communication performance than SLT combined with placebo…
- Trial name
- NCT03930121
- Testing
- Anodal transcranial direct current stimulation (tDCS) combined with speech-language therapy (SLT, including naming therapy and communicative-pragmatic therapy)
- Where
- 19 sites in Germany
- Volunteers
- 130 people
- Sponsor
- University Medicine Greifswald
Aphasia, Stroke
Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
Post-stroke aphasia (PSA), the partial or total loss of the ability to produce and/or understand language associated with stroke, is a highly prevalent and disabling disorder that negatively impacts the personal, social and…
- Trial name
- NCT04134416
- Testing
- Donepezil, Intensive-Language Action Therapy, Transcranial direct current stimulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Aphasia
Voice Adaptive Tablet-Based Naming Treatment for Adults With Aphasia
Rising life expectancy is leading to a rising incidence of strokes worldwide. Approximately one third of people who had a stroke live with a communication disorder, aphasia, which is associated with the largest negative…
- Trial name
- VoiceAdapt (NCT04108364)
- Testing
- Voice adaptive training for aphasia
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Aphasia, Stroke
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life.
- Trial name
- NCT05653440
- Testing
- Accuracy-maximized condition, Effort-maximized condition, Effort-accuracy balanced condition
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Aphasia
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
The current standard of care for rehabilitation of patients with aphasia after stroke is conventional speech and language therapy (SLT).
- Trial name
- NORTHSTAR (NCT02020421)
- Testing
- rTMS, tDCS
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 63 people
- Sponsor
- Dr. Alexander Thiel
Aphasia, Broca's Aphasia
Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation
The purpose of this study is to help us understand if adding transcranial Direct Current Stimulation (tDCS), a non-invasive brain stimulation technique, to Speech Therapy improves language recovery in people with Broca's aphasia…
- Trial name
- STARS (NCT07688551)
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- University of South Carolina
Aphasia Non Fluent, Stroke
Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke Aphasia
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that…
- Trial name
- SEMO (NCT04433351)
- Testing
- Enriched rehabilitation, Simple rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Aphasia, Virtual Reality
The Impact of Virtual Reality on the Emotional State of Patients With Aphasia During Rehabilitation.
The aim of the study is to determine virtual reality (VR) impact during standard program of rehabilitation on emotional state of patients with aphasia.
- Conditions
- Aphasia, Virtual Reality, Emotional Disturbances
- Trial name
- NCT04533308
- Testing
- Relaxation in virtual reality
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Aphasia, Primary Progressive, Anomia
Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia
The goal of this study is to remediate word-finding problems in patients who have Primary Progressive Aphasia (PPA) or Alzheimer's Disease and to delay the further progression of word-finding impairment.
- Conditions
- Aphasia, Primary Progressive, Anomia, Alzheimer Disease
- Trial name
- NCT02675270
- Testing
- Phonological, Orthographic, Semantic
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Georgetown University
Stroke, Brain Injuries
Clinical Effectiveness of iReadMore for People With Alexia
iReadMore will provide an app-based therapy for people with pure or central alexia. This study aims to test the clinical effectiveness of iReadMore for improving reading accuracy and speed in real world users of the therapy.
- Conditions
- Stroke, Brain Injuries, Aphasia, Alexia
- Trial name
- NCT04849091
- Testing
- iReadMore
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Aphasia, Stroke
Enhancing Written Communication in Persons With Aphasia
The purpose of this study is to evaluate whether a computerized speech-language treatment delivered by a virtual therapist (Oral Reading for Language in Aphasia (ORLA) + Writing) results in improved written communication skills…
- Trial name
- NCT01790880
- Testing
- ORLA, ORLA + Writing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
An Investigation of Constraint Induced Language Therapy for Aphasia
The purpose of this study is to investigate the effects of intensive, constraint induced language therapy (CILT) for individuals with chronic aphasia compared with traditional aphasia therapy.
- Trial name
- NCT00223847
- Testing
- Constraint Induced Language Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Stroke, Aphasia
Digital Interventions in Neurorehabilitation: iTALKbetter
iTALKBetter will provide an app-based therapy for people with word retrieval difficulties who have had a stroke. This study aims to test the therapy application for people with naming difficulties through a small scale…
- Conditions
- Stroke, Aphasia, Anomia
- Trial name
- NCT04566081
- Testing
- iTalkBetter Trained Items, iTalkBetter Untrained Items
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University College, London
Aphasia, Acquired
Effects of rTMS on Brain Activation in Aphasia
This study will investigate the use of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation method, to improve word-finding abilities in Veterans and non-Veterans with chronic language problems…
- Trial name
- NCT03292471
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Aphasia Following Cerebral Infarction
Application of Cerebellar tDCS in Aphasia
The goal of this clinical trial is to learn if adding brain stimulation (cerebellar anodal tDCS) helps a computer-based therapy improve word-finding in Cantonese-speaking adults with aphasia after stroke.
- Trial name
- NCT07353879
- Testing
- anodal right posterolateral cerebellar high-definition tDCS, computerized visual speech perception naming intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 6 people
- Sponsor
- The University of Hong Kong
Aphasia
Web-Based Treatment for Aphasia
This prospective randomized clinical trial implements an innovative broadband web-based treatment program for individuals with chronic aphasia, and evaluates its efficacy.
- Trial name
- Web-ORLA (NCT04413136)
- Testing
- Web-ORLA, Control
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Broca's Aphasia
Virtual Reality Based Sensorimotor Speech Therapy
The purpose of this study is to determine whether VR based language rehabilitation scenario based on the core premises of ILAT has a beneficial effect on the linguistic performance (faster retrieval of the target lexicon and…
- Trial name
- NCT02928822
- Testing
- VR-based sensorimotor aphasia therapy, Control Group (conventional aphasia rehabilitation)
- Where
- 2 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Universitat Pompeu Fabra