Clinical trials: Apical Prolapse
Apical Prolapse
Evolution of Symptoms After Sacrospinofixation With Posterior Isthmic Band
Prolapse is a condition that can cause disabling pelvic, urinary or sexual function disorders and impaired quality of life. Regarding the prolapse of the middle floor, the vaginal sacrospinofixation according to Richter is the…
- Trial name
- SPIP (NCT03911778)
- Testing
- Improvement of symptoms
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Pelvic Organ Prolapse
Effects of the Addition of Uterosacral Ligament Plication to Pectopexy Operation on Anatomical and Subjective Symptoms
The investigators planned to measure the effectiveness of laparoscopic pectopexy in apical prolapse and whether the addition of sacrouterine ligaments plication to pectopexy increases the effectiveness of pectopexy operation.
- Trial name
- NCT04508062
- Testing
- pectopexy operation, uterosacral ligaments plication operation.
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ataturk University
Constipation, Surgical Procedure, Unspecified
Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation.
- Conditions
- Constipation, Surgical Procedure, Unspecified, Prolapse; Female
- Trial name
- NCT06159777
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse, Pelvic Floor Prolapse
Laparoscopic Lateral Mesh Suspension for Pelvic Organ Prolapse
This study is aimed to share our clinical experience in an uterine-preserving laparoscopic lateral suspension of apical prolapses with mesh operation after minor modifications in technique.
- Trial name
- NCT03387202
- Testing
- Laparoscopic lateral suspension with mesh, Transperineal ultrasound
- Volunteers
- 15 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pelvic Organ Prolapse
Robotic-assisted Laparoscopic Sacrocolpopexy
Robotic-assisted Abdominal Sacrocolpopexy is both a feasible and safe method for apical prolapse repair of the vagina.
- Trial name
- NCT00581334
- Testing
- Robotic-assisted laparoscopic sacrocolpopexy, Open sacrocolpopexy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Pelvic Organ Prolapse
Apical Support During Hysterectomy for Pelvic Organ Prolapse-NSQIP Analysis.
This is a retrospective descriptive study using the American College of Surgeon's National Surgical Quality Improvement Program® (ACS NSQIP®) data to determine whether gynecologic surgeons are already meeting the recently…
- Trial name
- NCT03421067
- Where
- United States
- Volunteers
- 3,458 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery
To Explore the Surgical Outcomes and Safety of an Innovative Laparoscopic Uterine Pectopexy Technique Using Inverted T-meshes for Simultaneous Apical and Anterior Vaginal Repair.
Patients referred for pelvic reconstructive surgery frequently present with combined anterior and apical vaginal wall prolapse. Previous studies found that anterior compartment involvement is the most common and serious defect…
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery, Pectopexy, Sacrocolpopexy
- Trial name
- NCT07411898
- Testing
- Laparoscopic pectopexy, Laparoscopic sacrocolpopexy
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Chung Shan Medical University
Pelvic Organ Prolapse
A Surgical Simulation Study to Evaluate the Safety of a Device Mechanism as Treatment for Vaginal Apical Prolapse
The purpose of this pilot study is to perform a procedure to evaluate the safety of the placement of a new device (known as the VFIX device).
- Trial name
- NCT00965952
- Where
- 4 sites in Australia
- Volunteers
- 49 people
- Sponsor
- Ethicon, Inc.
Pelvic Organ Prolapse
Post-market Clinical Follow-up of the SRS Implant
National, multicentre observational study on surgical reconstruction of the anterior and apical compartment of the pelvic floor with an SRS implant
- Trial name
- NCT05170074
- Where
- 6 sites in Germany
- Volunteers
- 97 people
- Sponsor
- pfm medical gmbh
Pelvic Organ Prolapse
Lateral Suspension and Sacropexy for Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is considered one of the commonest gynecologic health problems all over the world. Pelvic organ prolapse (POP) is common and can be seen in up to 50% or more of parous women.
- Trial name
- NCT03772691
- Testing
- lateral suspension, sacropexy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
The Influence of Simultaneous Posterior Colporrhaphy and Perineoplasty on the Efficiency and Safety of Mesh-augmented Sacrospinal Fixation (Apical Sling) in Advanced POP Repair.
This is a prospective randomized controlled study, designed to assess the influence of posterior colporrhaphy and perineoplasty performed simultaneously with mesh-augmented sacrospinal fixation (apical sling) in advanced pelvic…
- Trial name
- NCT05422209
- Testing
- Mesh-augmented sacrospinal fixation with posterior colporrhaphy and perineoplasty., Mesh-augmented sacrospinal fixation with posterior colporrhaphy.
- Where
- Russia
- Volunteers
- 310 people
- Sponsor
- Saint Petersburg State University, Russia
Pelvic Organ Prolapse
Comparison of Mesh-Based and Mesh-Free Laparoscopic Pectopexy in Uterus-Preserving Surgery for Apical Prolapse
This retrospective cohort study compares anatomical and functional outcomes of mesh-based and mesh-free laparoscopic uterus-preserving pectopexy in women with apical pelvic organ prolapse.
- Trial name
- PectoMesh (NCT07080957)
- Testing
- Mesh-free laparoscopic uterus-preserving pectopexy, Mesh-based laparoscopic uterus-preserving pectopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Havva Betül Bacak
Pelvic Organ Prolapse, Surgical Procedure, Unspecified
Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled Trial
Pelvic organ prolapse (POP) is a common problem among women. Apical prolapse (AP) is a prolapse of the uterus, or vaginal cuff, in women post hysterectomy.
- Trial name
- NCT04306250
- Testing
- Apical prolapse fixation - anterior access, Apical prolapse fixation - posterior access
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study
The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Mesh Reinforcement, Vaginal Apex/Uterine Prolapse
- Trial name
- NCT07359755
- Testing
- Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- University of Sao Paulo General Hospital
Infertility, Female, Pelvic Organ Prolapse
Apical Pelvic Support in Infertility Patients
This study aims to evaluate apical pelvic compartment support in infertility patients at the time of hysteroscopy. Apical pelvic compartment evaluation for pelvic organ prolapse will be performed in infertility patients…
- Conditions
- Infertility, Female, Pelvic Organ Prolapse, Pelvic Floor Disorders
- Trial name
- NCT04039009
- Testing
- Pelvic Organ Prolapse Quantification system
- Where
- Turkey (Türkiye)
- Volunteers
- 1,100 people
- Sponsor
- Uludag University
Uterine Prolapse, Vault Prolapse
Laparoscopic Sacral Colpopexy Versus Modified Total Pelvic Floor Reconstructive Surgery for Apical Prolapse Stage III-IV
Pelvic Organ prolapse (a feeling of bulge in the vagina) may cause some distressing symptoms such as loss of control of the bowel or bladder, and may also cause problems with patient's sex life. The primary treatment is surgery.
- Trial name
- NCT01762384
- Testing
- LSC, modified PFRS, "Gynemesh"
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
This study will recruit women scheduled to undergo vaginal apical suspension surgery (either uterosacral ligament suspension or sacrospinous ligament fixation) with or without other prolapse or anti-incontinence procedures.
- Trial name
- NCT05658887
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joseph Kowalski
Visceral Prolapse
Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design
The study is a multi-center, randomized, surgical trial of women with symptomatic post-hysterectomy apical (cuff) prolapse desiring surgical treatment.
- Trial name
- ASPIRe (NCT02676973)
- Testing
- Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
- Where
- 10 sites in United States
- Volunteers
- 360 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Apical Prolapse
Sacro-hysteropexy Using Proline Mesh Versus Mersilene Tape in Apical Prolapse
Sacro-hysteropexy Using Proline Mesh Versus Mersilene Tape in Apical Prolapse: a Randomized Controlled Study .Aim of This Study is to Compare Between Using Poly-proline Mesh Versus Mersilene Tape in Abdominal Sacrohysteropexy…
- Trial name
- hystropexy (NCT05196542)
- Testing
- patients with apical prolapse who will do Sacro hysteropexy using mersilene tape
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mohamed Elsibai Anter
Pelvic Organ Prolapse
POPQ Versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair During Vaginal Reconstruction
The objective of the Preoperative Pelvic Organ Prolapse Quantification (POPQ) versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair at the Time of Transvaginal Apical Suspension (PREPARE) trial is to…
- Trial name
- NCT03187054
- Testing
- anterior or posterior colporrhaphy
- Where
- South Korea
- Volunteers
- 335 people
- Sponsor
- Seoul National University Hospital