Clinical trials: Apnoea
Obstructive Sleep Apnea, Hypertension
Cardiorespiratory Responses to Exercise in Elderly
Elderly have a high prevalence to systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA). Both comorbidities are closely associated and inflict injury cardiorespiratory capacity.
- Trial name
- NCT03307928
- Testing
- Cardiopulmonary Exercise Test Protocol, Polysomnography Assessment
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Paraíba
Pregnancy Related, Sleep Disordered Breathing
The Sleep in Pregnancy Study
Sleep disordered breathing (SDB) insidiously worsens metabolic function, heightens insulin resistance (IR), and in pregnancy is thought to precipitate gestational diabetes, preterm birth, growth restriction, gestational…
- Conditions
- Pregnancy Related, Sleep Disordered Breathing, Obesity
- Trial name
- SiP (NCT03248219)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sleep Apnea
Janus II Feasibility
The objectives of this study are to evaluate the feasibility of the remedē® Dual Channel System at implant and overnight sleep studies and to assess chronic safety.
- Trial name
- NCT06556693
- Testing
- Dual Channel Stimulation
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Zoll Medical Corporation
Sleep Apnea, Obstructive
CALLSAS Study: Effect of Continuous Positive Airway Pressure Treatment for Obstructive Apnea on Phone Usage Habits
Continuous positive airway pressure (CPAP) treatment improves sleepiness, depression and social activities in patients with obstructive sleep apnea (OSA).
- Trial name
- CALLSAS (NCT03537066)
- Testing
- CPAP
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Grenoble
OSA
A Cross Over Case Control Study of a Vibration Positional Device for Treatment of OSA
Positional therapy is considered as a kind of conservative treatment especially for patients with OSA which varies with body positions, and has been reported to be useful in selected cases especially those with positional OSA.
- Trial name
- NCT02613975
- Testing
- positonal device
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Obesity Hypoventilation Syndrome
Usefulness of Transcutaneous Capnography to Assess Residual Hypoventilation in Obesity-Hypoventilation Syndrom Treated by Non Invasive Ventilation at Home : a Prospective Study
Transcutaneous capnography (PtcCo2) recently showed good agreement with blood gases to assess hypercapnia. There is no study that has evaluated the benefit to realise systematically a nocturnal PtcCo2 in the follow-up of…
- Trial name
- PtcCO2-SOH (NCT03572712)
- Testing
- No Interventional study
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Nantes University Hospital
Sleep Apnea, Obstructive, Exercise Training Therapy
Effects of an Individualized Training Program on Severity Markers of Obstructives Sleep Apnea/Hypopnea Syndrome (OSAS)
There are two types of treatments depending on the severity of Obstructive Sleep Apnea/Hypopnea Syndrome (OSAS): - for the treatment of severe (AHI> 30/h), the standard treatment is Continuous Positive Airway Pressure (CPAP).
- Trial name
- REEVASAS (NCT01256307)
- Testing
- training and educational program, educational program
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Montpellier
Upper Aerodigestive Tract Neoplasms, Obstructive Sleep Apnea-hypopnea Syndrome
Obstructive Sleep Apnea Syndrome In Patients Treated For Cancer Of The Upper Aerodigestive Tract
Prospective open-label, non-randomized, monocentric, cohort study, to assess the prevalence and severity of sleep apnea syndrome in patients treated for cancer of the upper aerodigestive tract.
- Trial name
- SAOS-K (NCT04262453)
- Where
- France
- Volunteers
- 142 people
- Sponsor
- Centre Hospitalier Sud Francilien
Obstructive Sleep Apnea
The Effect of Melatonin on Sleep and Ventilatory Control in Obstructive Sleep Apnea
Our hypothesis is that oxidative stress induced during repeated apneas in obstructive sleep apnea (OSA) patients alters the neural control of breathing which destabilizes ventilatory control and exacerbates OSA.
- Trial name
- NCT02484300
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Stroke, Sleep Apnea Syndrome (OSAS)
Sleep and Stroke Rehabilitation Study
The study aims to map sleep disorders and their impact on the ability to engage in an active daily life among people who have had a stroke, with particular focus on how sleep apnea can be identified.
- Conditions
- Stroke, Sleep Apnea Syndrome (OSAS), Insomnia, Excessive Daytime Sleepiness
- Trial name
- SnSRehabS (NCT07579871)
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Malin Eleonora av Kák Gustafsson, MD, PhD
Decrease of Inflammation of Adipose Tissue, Sleep Apnea Syndrome
Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
The main objective of this study is to evaluate the decrease of inflammation of adipose tissue in obese and non-obese patients having a sleep apnea syndrome and treated or not by continuous positive airway pressure (cPAP).
- Trial name
- ADISAS (NCT01196845)
- Testing
- cPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy
This clinical trial will evaluate the effect of treatment with hypoglossal nerve stimulation on the underlying mechanisms of obstructive sleep apnea.
- Trial name
- HNS-CoDSE (NCT07337239)
- Testing
- Additional measurements during clinical standard follow-up drug-induced sleep endoscopy (DISE)
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea, Sleep-Disordered Breathing
Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimulation Therapy
Hypoglossal nerve stimulation (HNS) plays an increasingly important role in managing patients with obstructive sleep apnea (OSA) who do not tolerate CPAP therapy and are not eligible for other alternative treatment options, such…
- Trial name
- NCT06154577
- Testing
- Ultrasonography
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital, Baselland
Obstructive Sleep Apnea, Insomnia
Web Based CBT-I in Patients With OSA and Insomnia
Obstructive sleep apnea (OSA) and insomnia often occur in the same patient. Recent studies have demonstrated the efficacy of cognitive behavioral therapy (CBT-I) in patients with insomnia and OSA.
- Trial name
- NCT04473534
- Testing
- web based cognitive-behavioral therapy
- Where
- Italy
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Sleep Apnea, Obstructive, Hepatocellular Carcinoma
Sleep Apnoea Syndrome and Hepatocellular Carcinoma
Obstructive sleep apnea (OSA), one of the most frequent respiratory diseases, could represent a major worsening factor in a non alcoholic steatohepatitis and neoplastic context.
- Conditions
- Sleep Apnea, Obstructive, Hepatocellular Carcinoma, Non Alcoholic Steato Hepatitis
- Trial name
- ECHAPS (NCT04190498)
- Testing
- Nocturnal oximetry
- Where
- France
- Sponsor
- University Hospital, Grenoble
Sleep Apnea
Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
The goal of this clinical trial is to test if bexagliflozin lowers the sleep apnea severity in adults who are overweight or obese with moderate to severe obstructive sleep apnea (OSA) compared with a placebo (look-alike substance…
- Trial name
- ADIPOSA (NCT05612594)
- Testing
- Bexagliflozin 20 mg
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Yale University
Atherothrombosis, Type 2 Diabetes
Aspirin Resistance and Sleep Apnea in Type-2 Diabetic Patients
Type-2 Diabetes and Sleep Apnea Syndrome (SAS) are both related to an increase in platelet activation. Type 2 diabetes is often associated with sleep apnea syndrome with a prevalence up to 60%.
- Conditions
- Atherothrombosis, Type 2 Diabetes, Obstructive Sleep Apnea Syndrome
- Trial name
- AREAS (NCT01788930)
- Testing
- CPAP
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Grenoble
Lung Diseases, Sleep Apnea Syndromes
SCOR in Neurobiology of Sleep--Intermediate Traits for Sleep Apnea
To determine intermediate traits for sleep apnea in a case-control study.
- Trial name
- NCT00005511
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Cervical Stabilization in Individuals With Obstructive Sleep Apnea
This study will be performed in people with obstructive sleep apnea, in which one group will receive treatment with cervical stabilization for six weeks and the control group will receive treatment after the interval of six weeks
- Trial name
- NCT03154970
- Testing
- Craniocervical flexion training
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Universidade Federal de Santa Maria
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