Clinical trials: Apnoea
Sleep Disordered Breathing (SDB), Sleep Apnea
Neurostimulation for Sleep Disordered Breathing (SDB)
This is a study to determine if the Lunair Alpha System is safe and effective for treating moderate to severe sleep disordered breathing.
- Trial name
- ECLIPSE 2 (NCT07243405)
- Testing
- Neuro stimulator implant
- Where
- Panama
- Volunteers
- 45 people
- Sponsor
- Lunair Medical
Coronary Artery Disease
Influence of Obstructive Sleep Apnea on the Severity of Coronary Artery Disease
It is widely accepted that coronary artery disease (CAD) is related to a high mortality. It is predicted that an increase of approximately 21.3 million cardiovascular events and 7.7 million cardiovascular deaths over 2010 to 2030…
- Trial name
- NCT04741022
- Where
- China
- Volunteers
- 255 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Insomnia
Ramelteon for Complex Insomnia in Veterans With PTSD
Obstructive sleep apnea is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares.
- Trial name
- DORMI (NCT03265951)
- Testing
- Ramelteon, Usual Care
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Obstructive Sleep Apnea of Adult
Endothelial Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA), a condition that affects a quarter of the Western adults, triples the risk for cardiovascular diseases and increases all-cause mortality.
- Trial name
- NCT03122639
- Testing
- Atorvastatin 10mg
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Columbia University
Sleep Apnea
Prodigy, a Level 2 Sleep Study Device, Validation Study
The Prodigy system, developed by Cerebra Medical Ltd, allows for the generation of the same information in the home that is currently only obtained in in-laboratory studies.
- Trial name
- NCT05115305
- Where
- 2 sites in United States, Canada
- Volunteers
- 84 people
- Sponsor
- Cerebra Medical
Obstructive Sleep Apnea
Effects of Two Different Amounts of Mandibular Protrusion in OSA Patients Using Mandibular Advancement Appliance
Obstructive sleep apnea (OSA) is a complex disease associated with repeated closure of the upper airway during sleep which causes excessive daytime sleepiness.
- Trial name
- MAA (NCT04079153)
- Testing
- Mandibular advancement Appliance
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Heart Failure, Sleep Apnea Syndromes
Oxygen Versus PAP for Sleep Apnea in Heart Failure
The purpose of this study is to compare three treatment modalities for central, or mixed obstructive and central, sleep apnea in patients with chronic heart failure and reduced ejection fraction.
- Trial name
- OPTIMAL-HF (NCT01807897)
- Testing
- Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, CPAP
The Outcome of CPAP Titration Under Sleep Endoscopy
The outcome of CPAP titration under sleep endoscopy: A randomized controlled crossover trial
- Conditions
- Obstructive Sleep Apnea, CPAP, DISE
- Trial name
- NCT03523013
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Primary Snoring, Obstructive Sleep Apnea
Analysis of Snore Sound Following Minimal Invasive Surgery in Sleep-disordered Breathing Patients
1. Background:The methods of anti-snore (treatment of snoring ) can be divided into conservative, invasive and minimal invasive treatment.
- Trial name
- NCT01955083
- Testing
- Pillar implant, Radiofrequency
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea Syndrome
Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Continuous Positive Airway Pressure (CPAP) is the standard treatment in patients with Obstructive Sleep Apnea Syndrome (OSAS). The goal of the study is to evaluate CPAP treatment duration recorded by the AL539 during attended…
- Trial name
- AL539 (NCT01441622)
- Testing
- AL539 (SRETT)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Air Liquide Santé International
The Screening and the Treatment of ECG Holter and Sleep Apnea
The Screening and the Treatment of ECG Holter and Sleep Apnea
Sleep quality affect working and learning performance; poor quality of sleep is one of the common problems of modern people. Traditionally, polysomnography is a recognized standard for sleep quality assessment.
- Trial name
- NCT05928923
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation, Atrial Flutter
Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring
A prospective cohort study to evaluate the association between various triggers encountered in daily life and induction of atrial arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia and premature atrial…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- TriggersAF (NCT05526170)
- Testing
- Devices for long-term monitoring of objective and subjective parameters of the body
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Vilnius University
Desaturation of Blood, Obesity
High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal (GI) endoscopy with the patient under deep sedation.
- Conditions
- Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea
- Trial name
- NCT03148262
- Testing
- The Comfort Flo system, The Salter nasal cannula
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Texas Southwestern Medical Center
Preeclampsia, Gestational Diabetes
The Association Between High Risk Pregnancy and Sleep-disordered Breathing
The aim of the present study is to establish, using polysomnographic criteria and prospective nature, whether sleep apnea in pregnancy is more prevalent in women with high risk pregnancies including preeclampsia, gestational…
- Conditions
- Preeclampsia, Gestational Diabetes, Premature Labor
- Trial name
- NCT01022619
- Where
- 2 sites in Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Fat Metabolism in OSA and COPD
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by an obstruction of the upper airways. The obstruction results in periods of intermittent hypoxia and re-oxygenation, which lead to increased…
- Conditions
- Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Obesity
- Trial name
- NCT02157844
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obstructive Sleep Apnea, Sleep Apnea
Do Endotypes Predict Response and Sequelae in OSA Patients
This study will investigate why some people have Obstructive Sleep Apnea (OSA) and how the underlying cause may relate to OSA manifestations (including sleepiness and high blood pressure) and response to different therapeutic…
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Sleep Apnea, Obstructive, Sleep
- Trial name
- ExPRESSION (NCT04875364)
- Testing
- Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of California, San Diego
Gastroesophageal Reflux Disease, Apnea Infants
Gastroesophageal Reflux and Cardiorespiratory Problems
Cardiorespiratory and gastroesophageal reflux events often coexist in infants in Neonatal Intensive Care Unit (NICU) thus leading to drugs over-prescription and delayed discharge.
- Conditions
- Gastroesophageal Reflux Disease, Apnea Infants, Desaturation of Blood, Bradycardia
- Trial name
- CR-GER (NCT03053609)
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Turin, Italy
Sleep Disorder
A Prospective Study to Evaluate the WP in Comparison to PSG in Patients Suspected of Sleep Disorders
The current study is a prospective blinded study to collect data regarding the performance of the WP device in detecting sleep disorders.
- Trial name
- NCT06093633
- Where
- 3 sites in United States, Israel
- Volunteers
- 600 people
- Sponsor
- Itamar-Medical, Israel
Obstructive Sleep Apnea-hypopnea
The Study of Sleep Disordered Breathing in Patients With Interstitial Lung Diseases
This was a cross-sectional observational study to evaluate the prevalence and predictive factors of SDB in ILD and to analyze the relationship between polysomnography (PSG) findings, pulmonary function, disease severity…
- Trial name
- NCT06012526
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Beni-Suef University
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