Clinical trials: Apoplexy; Brain
Cerebral Infarction
Cilostazol in Acute Ischemic Stroke Treatment (CAIST)
The purpose of this study is to study efficacy and safety of cilostazol use in patients with acute ischemic stroke.
- Trial name
- NCT00272454
- Testing
- Cilostazol, Aspirin
- Where
- 12 sites in South Korea
- Volunteers
- 468 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Cerebral Infarction
Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS)
Sarpogrelate (MCI-9042) is an antiplatelet drug that decreases 5-hydroxytryptamine (5-HT) levels in platelets via a blockade of 5-HT2 receptors; it has been used in atherosclerotic peripheral arterial disease.
- Trial name
- NCT00129805
- Testing
- MCI-9042, Aspirin
- Volunteers
- 1,510 people
- Sponsor
- Tanabe Pharma Corporation
Cerebrovascular Accident
A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
This is a multicenter, double-blind, randomized, placebo-controlled study designed to compare Botulinum Toxin Type A for Injection (HengLi®) with placebo on the efficacy and safety of treatment in post-stroke subjects with focal…
- Trial name
- NCT02280083
- Testing
- Botulinum Toxin Type A for Injection
- Volunteers
- 180 people
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
Shoulder Pain Chronic
An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
The goal of this research study is to investigate safety and gather initial effectiveness data for a new implanted device designed to treat chronic shoulder pain in chronic post-stroke subjects.
- Trial name
- BBPM (NCT00567541)
- Testing
- Battery Powered Microneuromodulator (BBPM)
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Bioness Inc
Acute Ischemic Stroke
Study to Assess the Safety and Efficacy of THR-18 When Administered to Patients Suffering Acute Ischemic Stroke and Treated With Tissue Plasminogen Activator (tPA)
This will be a randomized, double-blind, placebo-controlled, multi-center, multi-national, escalating dose, pilot study comparing two doses of THR-18 to placebo when administered to patients suffering acute ischemic stroke and…
- Trial name
- NCT01253512
- Testing
- THR-18
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Thrombotech Ltd.
Stroke, Motor Activity
Observational Study of Ischaemic Stroke
The rationale for this study is to facilitate future Phase II/III clinical trials and improve outcome for patients suffering residual disability after an ischaemic stroke.
- Trial name
- OSIS (NCT01859572)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- ReNeuron Limited
Cancer, Neurological Disorder
Bolus Pouch Feed Study
The primary aim of this study is to evaluate the impact of introducing a new enteral tube feed on health and feeding related quality of life.
- Conditions
- Cancer, Neurological Disorder, Gastrointestinal Dysfunction, Oral Complication
- Trial name
- NCT05822557
- Testing
- Bolus Pouch Feed
- Where
- 15 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Nutricia UK Ltd
Acute Stroke
APERIO® HYBRID Thrombectomy Device for Flow Restoration in Vessels of Patients Experiencing Acute Ischemic Stroke
This is a prospective, multicenter, single-arm, open-label, national Post-Market Clinical Follow-up study to collect comprehensive information on technical and clinical success and safety of the use of APERIO® Hybrid(17/21)…
- Trial name
- NCT04457479
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Acandis GmbH
Cerebrovascular Accident, Brain Ischemia
A Study of Effectiveness and Safety of Abciximab in Patients With Acute Ischemic Stroke (AbESTT-II)
The purpose of this study is to determine the effectiveness of abciximab in the treatment of acute ischemic stroke.
- Conditions
- Cerebrovascular Accident, Brain Ischemia, Acute Disease
- Trial name
- NCT00073372
- Testing
- Abciximab
- Volunteers
- 808 people
- Sponsor
- Centocor, Inc.
Stroke
WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients
To establish equivalence or incremental benefit to standard of care Ankle-Foot Orthosis (AFO) for patients with foot drop due to stroke, and to assess the functional improvement of ambulation and improved activities of daily…
- Trial name
- NCT01087957
- Testing
- WalkAide, Ankle-Foot Orthosis (AFO)
- Where
- 29 sites in United States
- Volunteers
- 495 people
- Sponsor
- Innovative Neurotronics
Atrial Fibrillation (Prevention of Stroke)
Real-Life Evidence on Stroke Prevention in SPAF
To obtain a better understanding on the comparative effectiveness of rivaroxaban and vitamin K antagonists (VKA) for stroke prevention in patients with non-valvular atrial fibrillation (SPAF) in a real-life setting
- Trial name
- RELIEF (NCT02485873)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonists
- Where
- Germany
- Volunteers
- 8,607 people
- Sponsor
- Bayer
Acute Ischemic Stroke
HRS-7450 Injection Phase II Clinical Trial for Acute Ischemic Stroke.
This study plans to enroll a total of 208 patients with Acute Ischemic Stroke (AIS) who present within 4.5 to 24 hours of symptom onset and meet the specified imaging criteria.
- Trial name
- NCT07233070
- Testing
- HRS-7450 Injection
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Atrial Fibrillation
Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter
A study for subjects with atrial fibrillation (AF) or atrial flutter who are diagnosed with left atrial (LA) or left atrial appendage (LAA) thrombus. The study will assign subjects to rivaroxaban for treatment of thrombi.
- Trial name
- X-TRA (NCT01839357)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 31 sites in Bulgaria, France and 5 more
- Volunteers
- 60 people
- Sponsor
- Bayer
Cerebrovascular Accidents
Function Benefits of a Myoelectric Elbow-Wrist-Hand Orthosis
The objective of this study is to evaluate the functional benefits of a myoelectric Elbow-Wrist-Hand orthosis for persons with upper limb paralysis caused by a cerebrovascular accident (CVA).
- Trial name
- NCT02544672
- Testing
- Myoelectric Elbow-Wrist-Hand orthosis
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Myomo
Stroke
Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities.
- Trial name
- NCT07681102
- Testing
- kTMP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Magnetic Tides
Acute Ischemic Stroke
Envi™-SR Randomized Controlled Trial for Endovascular Treatment of Ischemic Stroke
The study objective is to examine and compare clinical outcomes, as measured by Modified Rankin Scale (mRS) at 90 days (± 15 days) post treatment, and related performance characteristics of the Envi™-SR and concurrent parallel…
- Trial name
- ENVI RCT (NCT05107206)
- Testing
- Mechanical Thrombectomy using the Envi™-SR Thrombectomy device, Mechanical Thrombectomy using the Solitaire or Trevo Revascularization Device
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- NeuroVasc Technologies
Stroke, Acute, COVID-19
EPISODE-PS-COVID: hEad Pulse for Ischemic StrOke DEtection Prehospital Study During the COVID-19 Pandemic ( EPISODEPSCOVID )
Prehospital providers encounter patients with suspected stroke frequently. Stroke and COVID-19 are related potentially putting these healthcare workers at risk of COVID-19 infection.
- Trial name
- EPISODE-PH-COV (NCT04445493)
- Testing
- MindRhythm Harmony
- Where
- United States
- Volunteers
- 486 people
- Sponsor
- MindRhythm, Inc.
Acute Ischemic Stroke AIS
The STem Cell-derived Extracellular Vesicle Therapy In Acute Ischemic Stroke (STEVIA)
This is a multicenter open-label, single-arm, dose escalation phase I clinical trial to evaluate the safety and tolerability of SNE-101 in patients with acute ischemic stroke
- Trial name
- STEVIA (NCT06995625)
- Testing
- SNE-101
- Where
- 3 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- S&Ebio Co. Ltd.
Aspiration, Acute Ischemic Stroke
Safety and Efficacy of Intracranial Thrombus Aspiration Catheter in the Treatment of Acute Large-vessel Occlusive Stroke
A prospective, multicenter, single-arm objective performance criteria trial to investigate the safety and efficacy of SINOMED ADPAT for Recanalization Therapy in acute large-vessel occlusive stroke.
- Conditions
- Aspiration, Acute Ischemic Stroke, Large-vessel Occlusion
- Trial name
- NCT05101668
- Testing
- Intracranial Thrombosis Aspiration Catheter
- Where
- 6 sites in China
- Volunteers
- 26 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Muscle Spasticity, Stroke
OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity
This is a safety and efficacy study of onabotulinumtoxinA in poststroke patients with upper limb spasticity.
- Trial name
- NCT02145676
- Testing
- onabotulinumtoxinA
- Where
- 2 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- Allergan