Clinical trials: Apoplexy; Brain
Stroke
A Rehabilitation Therapy for Post-stroke Fatigue
Stroke is a leading cause of adult disability in the community. Fatigue affects about a third of stroke survivors. It results in difficulty taking part in everyday activities, and increases risk of hospitalization and death after…
- Trial name
- NCT02131532
- Testing
- A brief psychological intervention
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Edinburgh
Atrial Fibrillation, Ischemic Stroke
Precision Medicine in Ischemic Stroke and Atrial Fibrillation
The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk estimation that can inform management…
- Trial name
- PreMISe-AF (NCT04637087)
- Testing
- Atrial fibrillation risk electronic health record alert
- Where
- United States
- Volunteers
- 805 people
- Sponsor
- Massachusetts General Hospital
Post Stroke
Perception of Advanced Rehabilitation Technologies Among Post-Stroke Patients and Rehabilitation Staff
This observational study aims to assess the perception of advanced rehabilitation technologies among three key groups involved in stroke recovery: post-stroke patients, physicians specialized in Physical and Rehabilitation…
- Trial name
- P-TECH-AVC (NCT06986421)
- Testing
- completion of a structured questionnaire
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Brain Health
Brain Health in the Time of COVID-19
This is a nationwide research program to study the neurological effects of COVID-19. It is open to the public. Healthy individuals and individuals who are or have been infected with COVID-19 are encouraged to join the effort.
- Trial name
- NCT04438967
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Miro Health
Stroke
Randomized Trial of Transcranial Theta-burst Stimulation and Transcranial Direct Current Stimulation
Background: Stroke is a leading cause of adult disability. Non-invasive brain stimulation can induce significant and sustained improvements in functional outcome.
- Trial name
- NCT02031107
- Testing
- cTBS, cathodal tDCS
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Adrian Guggisberg
Stroke, Ischemic, Stroke Hemorrhagic
Clinical Investigation to Evaluate the Suitability of StrokeWave in Distinguishing Haemorragic From Ischaemic Strokes
This is a pilot, monocentric clinical investigation to evaluate the suitability of StrokeWave in distinguishing haemorragic from ischaemic strokes.
- Trial name
- NCT04622644
- Testing
- Device: clinical investigation microwave device class IIa not marked CE for stroke detection
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Umbria Bioengineering Technologies
Rheumatic Heart Disease
INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority
This program is a comprehensive evaluation of rheumatic valvular heart disease (RVHD), Atrial fibrillation (AF)/flutter and stroke.
- Trial name
- INVICTUS-VKA (NCT02832544)
- Testing
- Rivaroxaban (20 mg), Vitamin K antagonists (VKA)
- Where
- 139 sites in Botswana, Brazil and 23 more
- Volunteers
- 4,565 people
- Sponsor
- Population Health Research Institute
Stroke
The Effects of Augmented Reality Versus Virtual Reality
This randomized controlled trial aims to compare the effects of augmented reality (AR) and virtual reality (VR)-assisted treadmill gait training on balance and walking in individuals with stroke, within the framework of the…
- Trial name
- NCT07113093
- Testing
- Augmented Reality, Virtual Reality, Self Directed Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ankara Yildirim Beyazıt University
Stroke
PCMS Task After Moderate-to-severe Stroke
Researchers at the University of Pittsburgh are conducting a research study to see how combining brain, nerve, and hand stimulation affect hand movement after stroke.
- Trial name
- NCT05736653
- Testing
- Task-specific PCMS, PCMS-rest
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Utah
Fatigue, Stroke
Effects of Nutrition on Post Stroke Fatigue
Fatigue, which is commonly defined as a feeling of tiredness during or after usual activities, or a feeling of insufficient energy to initiate these activities, is one of the most common secondary conditions among patients…
- Trial name
- NUTRE-S (NCT05728229)
- Testing
- Supplement with SiderAl® Med
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cerebrovascular Disorder, Stroke
Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
Background: A stroke occurs when not enough blood reaches the brain. Sometimes stroke causes changes in certain brain matter. This is called white matter hyperintensity (WMH) and can lead to mental decline.
- Conditions
- Cerebrovascular Disorder, Stroke, Aging
- Trial name
- NCT03366129
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Apathy, Minor Stroke
Non-disabling Ischemic Cerebrovascular Event With Apathy
The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. However, few previous studies have focused on affective impairment after transient ischemic attack (TIA) and minor stroke.
- Conditions
- Apathy, Minor Stroke, Transient Ischemic Attack, Stroke
- Trial name
- NCT04917237
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Stroke, Acute
Electrical Stimulation of the Paretic Upper Limb in the Early Stroke Phase
This study evaluates the effect of electrical somatosensory stimulation (ESS) on the restoration of upper limb functioning in acute stroke patients.
- Trial name
- NCT02250365
- Testing
- Continuous, suprasensory ESS, Intermittent, suprasensory ESS
- Where
- 3 sites in Denmark
- Volunteers
- 102 people
- Sponsor
- University of Copenhagen
Stroke
Intranasal Insulin and Post-stroke Cognition: A Pilot Study
Almost two-thirds of survivors have cognitive impairment (CI), manifested as memory, language, and judgement problems. Post-stroke CI at 2 weeks is a significant predictor of long-term functional outcome, and more generally…
- Trial name
- NCT02810392
- Testing
- Intranasal Insulin, Intranasal saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Hyperglycaemia (Non Diabetic), Enteral Feeding Intolerance
Hyperglycemia in Patients with Stroke and Indication of Enteral Nutrition
The purpose of this study is to evaluate the effect of a specific nutritional formula for diabetics on the development of hyperglycemia in patients with recent non-diabetic stroke who require admission and enteral nutritional…
- Conditions
- Hyperglycaemia (Non Diabetic), Enteral Feeding Intolerance, Stroke
- Trial name
- GlyENStroke (NCT03422900)
- Testing
- Diabetes-Specific enteral formula, Standard formula
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Endocrinology and Clinical Nutrition Research Center, Spain
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Acute Ischemic Stroke, Cerebral Infarction
Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)
Stroke is the second leading cause of death worldwide, and ischemic stroke is the most frequent type. Intravenous thrombolysis with recombinant tissue plasminogen activator within 4.5 hours of symptom onset is the most effective…
- Trial name
- TREND-IVT (NCT06548971)
- Testing
- Aspirin, Best medical management
- Where
- 119 sites in China
- Volunteers
- 1,184 people
- Sponsor
- Capital Medical University
Brain Ischemia
Iron, Alpha-Synuclein, and Lymphocyte-activation Gene-3 in Ischemic Stroke
This observational study aims to detect levels of iron, alpha-synuclein, and soluble lymphocyte activation gene 3 in acute ischemic stroke patients.
- Trial name
- NCT05748587
- Testing
- Serum Iron, RBCs Alpha-synuclein, Serum Soluble lymphocyte activation gene
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Aswan University Hospital
Acute Ischemic Stroke
Evaluate the Efficacy and Safety of TTYP01 Tablets in the Treatment of Acute Ischemic Stroke
The study is designed as a multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy and safety of TTYP01 tablets in the treatment of acute ischemic stroke.
- Trial name
- NCT06648304
- Testing
- TTYP01 tablets
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Shanghai Auzone Biological Technology Co., Ltd.
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