Clinical trials: Apoplexy; Brain
Diabetes, Cardiovascular Disease
Associations Between Diabetes Care and Haptoglobin Genotype On outComes
The ADHOC Cohort comprised 3044 DM individuals, treated in 47 CHS primary care clinics, that underwent haptoglobin genotyping between 2 march, 2005 and 26 September 2006.
- Conditions
- Diabetes, Cardiovascular Disease, Myocardial Infarction, Stroke
- Trial name
- ADHOC (NCT00872456)
- Volunteers
- 3,054 people
- Sponsor
- Clalit Health Services
Stroke
Interdisciplinary Platform for Rehabilitation Research and Innovative Care of Stroke Patients
Observational study of functional recovery of stroke patients after discharge from rehabilitation
- Trial name
- ImPRoVe (NCT04119479)
- Where
- 6 sites in Germany
- Volunteers
- 227 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke
Optimization Principles in Hemiparetic Gait
This project seeks to identify the how walking impairments in stroke survivors contribute to mobility deficits through the use of behavioral observations and computational models.
- Trial name
- NCT03916562
- Testing
- Manipulation of spatiotemporal coordination during walking
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Oral Disease, Stroke, Ischemic
Oral Health in Patients Hospitalized Because of Ischemic Stroke
Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population.
- Trial name
- NCT06332846
- Testing
- oral examination
- Where
- Poland
- Volunteers
- 118 people
- Sponsor
- Pomeranian Medical University Szczecin
Stroke, Spinal Cord Injury
ERIGO® Life- Control of Cardiovascular Parameters Via Verticalization and Simultaneous Mobilization
Early verticalization and stepping with the equipment of Hocoma ERIGO during monitoring of vital parameters. The device is already CE marked and, for the purposes of the study, will be used in accordance with the intended use…
- Trial name
- ERIGO®LIFE (NCT02268266)
- Testing
- Erigo
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Stroke
Nintendo Wii® and Physical Therapy in Stroke Patients (NW-SP)
Brief Summary: In the present study a program which combines virtual rehabilitation through Nintendo Wii and conventional physical therapy is applied in stroke patients, evaluating functional capability (TUG), gait and balance…
- Trial name
- NW-SP (NCT04144556)
- Testing
- Nintendo Wii and conventional physical therapy, Conventional Physical therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Valencia
CVD
EEG/MECG/EMG Evaluating the Severity of Aortic Stenosis, Heart Failure and Ischemic Stroke Through an Artificial Intelligenceassisted System.
The specific objectives and methods of this project are: (1) To test the feasibility and accuracy of integrating EEG, MECG and EMG for detecting the severity of diseases such as aortic stenosis, heart failure and ischemic stroke.
- Trial name
- NCT05716659
- Where
- Taiwan
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Aortic Valve Disease, Aortic Valve Stenosis
Periprocedural Continuation Versus Interruption of Oral Anticoagulant Drugs During Transcatheter Aortic Valve Implantation (POPular PAUSE TAVI)
Transcatheter aortic valve implantation (TAVI) is a rapidly growing treatment option for patients with aortic valve stenosis. Stroke is a feared complication of TAVI, with an incidence of around 4-5% in the first 30 days.
- Conditions
- Aortic Valve Disease, Aortic Valve Stenosis, Stroke, Bleeding
- Trial name
- NCT04437303
- Testing
- Continuation of oral anticoagulants, Interruption of oral anticoagulants
- Where
- 22 sites in Belgium, Denmark and 4 more
- Volunteers
- 858 people
- Sponsor
- St. Antonius Hospital
Sturge - Weber Syndrome (SWS)
Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)
Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face.
- Trial name
- NCT00610402
- Testing
- blood sample tear drop sample
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, Irvine
Perinatal Stroke, Hemiplegic Cerebral Palsy
Stimulation for Perinatal Stroke Optimizing Recovery Trajectories
Perinatal stroke causes lifelong neurological disability and most hemiparetic cerebral palsy (CP). With morbidity spanning diverse aspects of a child's life and lasting for decades, global impact is large, including 10000…
- Trial name
- SPORT (NCT03216837)
- Testing
- Cathodal transcranial direct current stimulation
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- University of Calgary
Carotid Artery Disease
Proximal Protection With The Mo.Ma Device During Carotid Stenting
The objective of the ARMOUR study is to evaluate the safety and effectiveness of the Mo.Ma proximal flow blockage cerebral protection device for patients at high surgical risk for carotid endarterectomy who undergo carotid artery…
- Trial name
- ARMOUR (NCT00744523)
- Testing
- Mo.Ma cerebral protection device
- Where
- 2 sites in United States
- Volunteers
- 262 people
- Sponsor
- Medtronic Endovascular
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Acute Stroke
Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Acute Stroke Patients
Stroke is the principal cause of permanent disability within the investigators population. This incapacity justifies an intensive and prolonged multidisciplinary rehabilitation, which can be optimized by robotics.
- Trial name
- NCT02079779
- Testing
- Robotic-assisted therapy, Classical therapy
- Where
- 3 sites in Belgium
- Volunteers
- 45 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Ischaemic Stroke
The RETRAIN Trial Phase 2
Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom.
- Trial name
- RETRAIN 2 (NCT07197996)
- Testing
- Intermittent Pneumatic Compression, geko® T3
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- Firstkind Ltd
Stroke, Spasticity, Muscle
Individualized rTMS Based on fNIRS to Spasticity
Stroke is of high morbidity and mortality, and surviving patients are often unable to take care of themselves because of severe motor dysfunction.
- Conditions
- Stroke, Spasticity, Muscle, Rehabilitation
- Trial name
- NCT05318586
- Testing
- individual rTMS based on fNIRS, Traditional rTMS strategy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Stroke, Electroencephalogram
Correlates Between EEG Microstates and Clinical Characteristics of People With Stroke
Stroke has been considered one of the main causes of long-term disability in the adult population, and is no longer considered a disease of the elderly, since 2/3 of all strokes occur among people under 70 years of age.
- Trial name
- NCT05519631
- Testing
- electroencephalogram
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Fatigability Post Stroke
Evaluation of the Value of Cerebral Perfusion Scintigraphy in the Study of Post-stroke Fatigability
At present there is no consensus for post-stroke imaging except for the realization of early cerebral CT at 24 hours post-thrombolysis. The use of cerebral perfusion scintigraphy would predict the course of a stroke.
- Trial name
- NCT03543280
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Strasbourg, France
Ischemic Stroke, Remote Ischaemic Preconditioning
Effect of Remote Ischemic Preconditioning on Early Neurological Deterioration in Acute Perforating Artery Infarction
This study aims to conduct a prospective, randomized, double-blind, multicenter, parallel-controlled, group-sequential trialto scientifically evaluate the safety and efficacy of remote ischemic preconditioning (RIC) in preventing…
- Trial name
- RIC-END (NCT07237542)
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 910 people
- Sponsor
- Jinling Hospital, China
Ischemic Stroke
MSC Secretome and rTMS for Motor Recovery After Subacute Ischemic Stroke
This randomized, double-blind, controlled clinical trial evaluates the effectiveness and safety of combined mesenchymal stem cell (MSC) secretome and repetitive transcranial magnetic stimulation (rTMS) for motor recovery in…
- Trial name
- NCT07874269
- Testing
- Mesenchymal Stem Cell-Derived Secretome, Active Repetitive Transcranial Magnetic Stimulation
- Where
- Indonesia
- Volunteers
- 205 people
- Sponsor
- Jumraini Tammasse
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