Clinical trials: Apoplexy; Brain
Atherosclerosis
Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging
The goal of this study is to assess a slimy substance that settles/deposits along blood vessel wall. This slimy substance is called plaque. Plaque could be made up of fat, calcium or both. Plaque deposition narrows the vessels.
- Trial name
- NCT02114697
- Testing
- Statin therapy, Lifestyle modification
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Ischemic Stroke
Methanesulfonic Acid Cinepazide Injection for Treatment of Acute Cerebral Infarction
Using placebo as control, The purpose of this study is to evaluate the efficacy and safety of methanesulfonic acid cinepazide injection to relieve disabled degree of acute cerebral infarction patients, and explore the best safe…
- Trial name
- NCT01851759
- Testing
- cinepazide
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xijing Hospital
Acute Ischemic Stroke
Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema
This study is designed to evaluate the safety, efficacy, and pharmacokinetics of balovaptan compared with placebo in participants with acute ischemic stroke (AIS) at risk of developing Malignant Cerebral Edema (MCE)
- Trial name
- NCT05399550
- Testing
- Balovaptan
- Where
- United States
- Sponsor
- Hoffmann-La Roche
Intravenous, Thrombosis
Intravenous TNK vs TPA for AIS Treatment on MSU,a Prospective Multicenter RCT
Acute ischemic stroke is one of the devastating diseases that increase hospitalization, disabilities, and deaths worldwide. Current treatment with intravenous thrombolytic agent can help reduce disabilities and improve quality of…
- Conditions
- Intravenous, Thrombosis, Acute Ischemic Stroke
- Trial name
- NCT06498323
- Testing
- tenecteplase
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Stroke, Cardiovascular Risk Factors
Exercise and Brain Health
The risk of stroke and vascular dementia is high in individuals who have had a prior stroke or TIA, and in those who have vascular disease risk factors, such as high blood pressure, abnormal cholesterol, diabetes or pre-diabetes.
- Conditions
- Stroke, Cardiovascular Risk Factors, Transient Ischemic Attack (TIA)
- Trial name
- EBH (NCT02626442)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Stroke, Ischemic, Stroke, Acute
Ischemic Strokes While on NOAC - How Compliance Matters
This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Syndrome, Stroke, Cardiovascular
- Trial name
- NCT04607070
- Where
- Hong Kong
- Volunteers
- 91 people
- Sponsor
- Chinese University of Hong Kong
Stroke, Ischemic
Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)
The best reperfusion strategy for medium-sized vessel occlusion (MeVO) is not well established. Given the proven treatment effect of intra-arterial thrombolysis in patients with large vessel occlusion (LVO), the investigators…
- Trial name
- NCT05657470
- Testing
- Tenecteplase
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Shenyang Military Region
Ischemic Stroke, TIA
Cilostazol and Aspirin in Stroke and TIA
This study is a randomized, open-labelled trial. We randomly assigned patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA to combination therapy with cilostazol and aspirin or to clopidogrel plus…
- Trial name
- NCT06522113
- Testing
- Cilostazol, Clopidogrel
- Where
- South Korea
- Volunteers
- 378 people
- Sponsor
- Incheon St.Mary's Hospital
Stroke
Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the unaffected hemisphere (UH) transiently improves motor function in patients in the chronic phase after stroke.
- Trial name
- NCT01333579
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis
Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS)
The primary goal of the trial is to investigate whether the experimental arms (receiving the Proprotein Convertase Subtilisin-Kexin Type 9 [PCSK9] inhibitor Evolocumab plus statin) could cause more changes from baseline in…
- Trial name
- EAST-ICAS (NCT05741086)
- Testing
- Evolocumab, Atorvastatin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stroke
Active Smart Wearable Orthosis for Enhanched Rehabilitation THErapy
The purpose of this study is to investigate the usability of a new upper limb robot assisted therapy device in stroke patients.
- Trial name
- ARTHE (NCT03153254)
- Testing
- Test upper limb robot assisted therapy device, Training with new upper limb robot assisted therapy device
- Where
- 4 sites in Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas More Kempen
Dyslexia, Acquired, Brain Injuries
Therapy for Reading Problems in Adults After Brain Injury
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
- Conditions
- Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
- Trial name
- NCT00064805
- Testing
- Cognitive Therapy to Improve Reading
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke, Hemiplegia
Cardiovascular Function in Sub Maximal Exercise and Performance in Three Daily Activity Tests After Stroke
The purpose of this study is to explore the relationship between cardiovascular function of persons with post stroke conditions and their performance in three field tests.
- Trial name
- NCT01396746
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Stroke, Ischemic Stroke
Feasibility of a First-Line Physical Activity Intervention After Stroke
The goal of this study is to explore a new intervention that supports physical activity within the first 6 weeks after stroke. All participants will complete assessments at weeks 0 and 7.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- PA-ChatS (NCT06679803)
- Testing
- Physical Activity Chats after Stroke (PA-ChatS)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Minnesota
Stroke, Cerebrovascular Disorders
Transcranial Direct Current Stimulation Associate to Constraint Induced Movement Therapy Over Premotor Cortex in Severe Stroke
The purpose is to compare the effects of tDCS and constraint induced movement therapy (CIMT) in the premotor cortex vs. primary motor cortex in severely subacute stroke survivors.
- Conditions
- Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- NCT02628561
- Testing
- Transcranial direct current stimulation, Constraint-Induced Movement Therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Stroke
Atrial Cardiomyopathy in Patients With Stroke of Undetected Mechanism
The goal of this study is to evaluate left atrial structural and functional abnormalities in stroke of undetected mechanism and atherosclerotic stroke with cardiac MRI.
- Trial name
- NCT03830983
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Stroke
A Caregiver-mediated Intervention Improves the Functional Ability of Home-living Chronic Stroke Patients
To examine the feasibility of improving stroke patients' physical functional recovery and social participation through improving caregiver's care capability.
- Trial name
- NCT01693341
- Testing
- Care-giver mediated training
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Asia University
Ischemic Stroke
Efficacy and Safety Evaluation of 3K3A-APC in Ischemic Stroke
The purpose of this study is to evaluate the efficacy and safety of intravenous doses of 3K3A-APC, a recombinant variant of human activated protein C (APC), in the treatment of acute ischemic stroke following treatment with…
- Trial name
- RHAPSODY-2 (NCT05484154)
- Testing
- 3K3A-APC
- Sponsor
- ZZ Biotech, LLC
Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia
The Relationship Between Lower Limb Functionality, Foot Joint Position Sensation and Balance in Haemiplegic Patients
Stroke is defined as a neurological disorder resulting from acute focal damage to the central nervous system caused by vascular factors, which may include cerebral infarction, intracerebral haemorrhage and subarachnoid…
- Conditions
- Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia, Getting 20 Points or More in the Mini Mental Test, Volunteering to Participate in the Study
- Trial name
- NCT06043960
- Testing
- Humac Norm İsokinetic Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Stroke
Measurement of Cerebral Oxygen Extraction Fraction Using MRI Technique
All images in this study were acquired on a 1.5 T Sonata whole body scanner (Siemens Medical Inc., Erlangen, Germany) using 2D multi-echo gradient echo/spin echo sequence and 2D single-shot gradient echo-planar imaging sequence…
- Trial name
- NCT00166920
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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