Clinical trials: Apoplexy; Brain
Ischemic Stroke, Hemorrhagic Stroke
A Novel Transition Program to Reduce Disability After Stroke
This study evaluates a program designed to help individuals transition home from inpatient rehabilitation following an ischemic or hemorrhagic stroke.
- Trial name
- COMPASS (NCT03485820)
- Testing
- COMPASS, Stroke education
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Washington University School of Medicine
Acute Ischemic Stroke
Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)
To explore the safe and efficacious dose of rhTNK-tPA injection administered within 3 hours after onset of hyperacute ischemic stroke; to provide dose evidence for phase III clinical trial.
- Trial name
- NCT04676659
- Testing
- TNK-tPA
- Where
- 24 sites in China
- Volunteers
- 240 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic, Cerebrovascular Accident
The Effects of Blood Flow Restriction With Low-intensity Resistance Training Versus Traditional Resistance Exercise on Lower Limb Strength, Walking Capacity, and Balance in Patients With Ischemic Stroke: (BFR-Stroke RESILIENCE Trial)
Stroke is the leading neurological disease in the world that causes long-term disability. The most common cause of disability after stroke is motor impairment resulting from brain damage which ultimately causes mobility and…
- Trial name
- NCT05281679
- Testing
- Low-intensity resistance exercise with blood flow restriction group (L-BFR), High-intensity resistance exercise without blood flow restriction group (H-BFR).
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Ischemic Stroke, Acute
Accuracy of Transcranial Colour Coded Duplex in Comparing With CT Angiography
Investigator will compare accuracy of transcranial colour coded duplex with CT angiography in detecting arterial obstructions in patients presenting or with history of cerebrovascular ischemic strokes
- Trial name
- NCT06920303
- Testing
- transcranial colour coded duplex
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Dysphagia
Comparison of Ultrasound and Videofluoroscopic Imaging Techniques in Diagnosing Dysphagia in Stroke Patients
Introduction Patients with stroke may be silent aspirators or at risk for laryngeal penetration or aspiration because of abnormal oropharyngeal functioning and thus are at risk for aspiration pneumonia and its serious effects.
- Trial name
- NCT01249300
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Stroke
Tailored Approaches to Stroke Health Education
The overarching goal of the proposed intervention is to reduce stroke disparities by overcoming pre-hospital barriers related to emergency stroke treatment and facilitating the appropriate response to acute stroke using a novel…
- Trial name
- TASHE (NCT01909271)
- Testing
- Stroke Education Film Viewing, Stroke Education Pamphlet Exposure
- Where
- 2 sites in United States
- Volunteers
- 290 people
- Sponsor
- Columbia University
Cerebral Hypoxia, Ischemic Stroke
Thrombo-inflammation Biomarkers Trial in Acute Cerebral Hypoxia
The goal of this trial is to study, in three well-defined clinical situations responsible for cerebral hypoxia, the concentrations of biomarkers of thrombo-inflammation compared to a population of patients without cerebral…
- Trial name
- RADICAL (NCT04971564)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke
TENS and Spasticity in Stroke Patients
study aims to evaluate the efficacy of high and low frequency TENS on spasticity, strength and functional status in stroke patients.
- Trial name
- NCT05075109
- Testing
- High Frequency TENS, Low Frequency TENS, Task Related Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Carotid Artery Diseases
TCAR Cerebral Protection And MicroNET-Covered Stent To Reduce Strokes
Prospective, single center clinical study in consecutive patients with symptoms or signs of carotid stenosis related ischemic cerebral injury undergoing carotid revascularization in primary and secondary stroke prevention.
- Trial name
- TOP-GUARD (NCT04547387)
- Testing
- Trans-carotid access revascularization with MicroNET covered stent implantation
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Stroke
Immersive Virtual Reality in Stroke Pilot Study
Over 15,000 Veterans are treated by the VA for stroke each year. A stroke means that part of the brain dies. Many people who have a stroke have difficulty with moving their arm, using their hand, and they have pain.
- Trial name
- VR (NCT04429945)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Office of Research and Development
Stroke
Clinical Validation of an Artificial Intelligence-Based G-FAST Score in Patients With Stroke
This study aims to validate the clinical performance of an artificial intelligence (AI)-based automatic assessment system for the G-FAST score.
- Trial name
- NCT07538492
- Volunteers
- 297 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window (ImpACT-24A)
The primary objective of the study is to assess the safety and effectiveness of SPG stimulation with the ISS in patients with an acute ischemic stroke in the anterior circulation initiated within 24 hours from stroke onset.
- Trial name
- ImpACT-24A (NCT03767192)
- Testing
- Active Stimulation
- Where
- 8 sites in United States, Germany and 1 more
- Volunteers
- 327 people
- Sponsor
- BrainsGate
Stroke
FIRST-Oslo Long-term Follow-up
The study aims to describe the functional level of the patients who received high intensity gait training during inpatient stroke rehabilitation at discharge, three, six and twelve months after stroke.
- Trial name
- NCT04870619
- Testing
- High Intensity Gait Training
- Where
- 2 sites in Norway
- Volunteers
- 69 people
- Sponsor
- Oslo University Hospital
Stroke, Upper Extremity Paresis
Virtual Reality Based Mirror Therapy
The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.
- Conditions
- Stroke, Upper Extremity Paresis, Upper Extremity Paralysis
- Trial name
- NCT06152328
- Testing
- Virtual reality applications based on mirror therapy, Conventional treatment, Mirror therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Abant Izzet Baysal University
Cerebrovascular Accident
Rt-PA in the Treatment of Acute Ischemic Stroke
To collect additional confirmatory data on alteplase(rt-PA) in the European setting and to demonstrate that the treatment of patients between 3 and 4.30 hours of onset of symptoms of acute ischemic stroke with rt-PA compared to…
- Trial name
- NCT00153036
- Where
- 142 sites in Austria, Belgium and 17 more
- Volunteers
- 821 people
- Sponsor
- Boehringer Ingelheim
Acute Ischemic Stroke
A Clinical Trial of MT200605 for the Treatment of Acute Ischemic Stroke
MT200605 is an agonist of the receptor tyrosine kinase B (TrkB). It exerts brain-derived neurotrophic factor (BDNF)-like effects, protecting the structure and function of neural tissues in the brain.
- Trial name
- NCT07205328
- Testing
- MT200605
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shaanxi Micot Pharmaceutical Technology Co., Ltd.
Stroke
Efficacy and Safety of Salvianolic Acid on AIS
Stroke has the characteristics of high morbidity, disability and fatality rate, which brings heavy spiritual and economic burdens to the family, society and the country.
- Trial name
- NCT04931628
- Testing
- Salvianolic Acid, 0.9% NaCl
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Parkinson Disease
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
The purpose of this study is to evaluate the feasibility and efficacy of a smart airbag system that detects and mitigates fall-related impact in individuals with high fall risk.
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Knee, Fall Injury
- Trial name
- NCT05076565
- Testing
- Airbag Belt Fall Protection System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Cerebrovascular Accident
A Post Discharge Intervention to Improve Stroke Outcomes
The purpose of this randomized controlled trial (RCT) is to test the effectiveness of a comprehensive interdisciplinary post-discharge stroke care management intervention in improving the overall well-being of 190 stroke…
- Trial name
- NCT00328471
- Testing
- care management
- Volunteers
- 380 people
- Sponsor
- Summa Health System
Stroke
Robotic Telerehabilitation of the Upper Limb in Stroke
The goal of the study is to investigate the feasibility and the effects of a home-based upper-limb rehabilitation treatment (based on teleconsulting, telemonitoring, and robotic telerehabilitation using the robot Icone and…
- Trial name
- TELEREHAB (NCT05250934)
- Testing
- Robotic rehabilitation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
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