Clinical trials: Apoplexy; Brain
Stroke, Multiple Sclerosis
Improving Social Cognition and Social Behaviour in Various Brain Disorders
Impairments in aspects of social cognition are disorder-transcending: these have been demonstrated in various neurological disorders, such as traumatic brain injury (TBI), stroke, brain tumours (both low grade glioma's and…
- Conditions
- Stroke, Multiple Sclerosis, Brain Tumor
- Trial name
- T-ScEmo4ALL (NCT06330298)
- Testing
- Treatment social cognition and emotion regulation (T-ScEmo)
- Where
- 2 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- University Medical Center Groningen
Stroke, Acute
Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients
We want to determine if treating acute ischemic stroke patients who have evidence of hypoxemia due to sleep apnea with low flow O2 during sleep might help improve clinical and functional outcomes.
- Trial name
- NCT03300063
- Testing
- Low flow nocturnal oxygen
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Stroke, Ischemic Stroke
Dietary Intervention With the Modified Atkins Diet in Stroke Rehabilitation
This phase 1 study tests whether use of the Modified Atkins Diet (MAD) can improve motor impairment after stroke. It is based on the hypothesis that after stroke, the brain's utilization of glucose, it's primary source of energy…
- Trial name
- NCT01820663
- Testing
- Modified Atkins Diet, Control diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Burke Rehabilitation Hospital
Stroke
Self-Managed Exercise in Chronic Stroke
This pilot study will assess the feasibility of a novel intervention to promote long-term self-managed exercise for post-stroke community-dwelling individuals.
- Trial name
- NCT07799987
- Testing
- Exercise, Behavioral Management Program
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Stroke
The Effects of Extracorporeal Shock Wave Therapy on Upper Extremity Spasticity and Function in Patients With Stroke
Spasticity is a common complication after stroke and can limit upper extremity motor control and activities of daily living. Radial extracorporeal shock wave therapy (rESWT) is a non-invasive treatment that has been investigated…
- Trial name
- NCT07532187
- Testing
- Radial Extracorporeal Shock Wave Therapy (rESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Stroke, Osteoporosis
Assessment and Comparison of Osteoporosis Risk Factors After Stroke
The aim of this study is to evaluate the effects of stroke and associated clinical, functional, nutritional, and muscular factors, including handgrip strength, on bone mineral density and osteoporosis by comparing patients with…
- Trial name
- NCT07228611
- Testing
- Bone Mineral Density
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Stroke
Revascularization Pretreated With Fingolimod in Acute Stroke
Acute ischemic stroke (AIS) is a common type of stroke in the elderly. Timely blood flow recovery can effectively improve the long-term prognosis of patients.
- Trial name
- REPAIR FAST (NCT04718064)
- Testing
- Fingolimod
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Stroke
Non-invasive Auricular Vagus Nerve Stimulation (taVNS) on Postural Control and Autonomic Responses in Stroke
This randomized controlled trial is conducted to determine the effects of transcutaneous auricular Vagus nerve stimulation (taVNS) on postural control in stroke patients (e.g., improvements in balance, mobility, and functional…
- Trial name
- NCT07629687
- Testing
- Vagus Nerve Stimulation combined with Balance Training Group, Balance Training Group
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ischemic Stroke, Digital Health
Prevention of Ischemic Stroke Recurrence Using Digital Technology Application
The goal of this study is to find out whether a comprehensive management program that uses a smart bracelet and a mobile app can help people who have had an ischemic stroke (a type of stroke caused by a blocked blood vessel in…
- Trial name
- DESIRE (NCT07825311)
- Testing
- Digital Prevention Management, Usual Stroke Secondary Prevention Management
- Where
- China
- Volunteers
- 1,696 people
- Sponsor
- Affiliated Hospital of Nantong University
Stroke
Effect of Intensive Cognitive Rehabilitation on Cognitive, Motor, and Language Functional Networks in Subacute Stroke Patient
Altered brain networks, including cognitive, motor, and language networks, are investigated by intensive cognitive rehabilitation in subacute stroke patients.
- Trial name
- NCT05254964
- Testing
- Cognitive rehabilitation
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Stroke, Hemiplegia
Virtual Reality-Based Balance Training in Hemiplegic Patients
This prospective single-blind randomized controlled trial enrolled 43 hemiplegic patients hospitalized in the neurological rehabilitation unit of the University of Health Sciences Ankara Etlik City Hospital.
- Trial name
- NCT07475598
- Testing
- VR-Based Balance Training, Routine Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gaziantep City Hospital
Acute Ischemic Stroke (AIS)
A Phase I Clinical Trial Evaluating the Safety, Tolerability and Pharmacokinetics of AAPB for Injection
This is a Phase I clinical to evaluate the safety and tolerability of single and multiple intravenous infusions of AAPB at different doses over 7 consecutive days.
- Trial name
- AAPB (NCT06679998)
- Testing
- Single dose, AAPB by injection, intravenous drip., Multiple dosing, AAPB for injection, intravenous drip
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Mitral Valve Stenosis, Atrial Fibrillation
Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis
This study aims to compare the efficacy and safety of the edoxaban and the warfarin in atrial fibrillation patients with mitral stenosis.
- Conditions
- Mitral Valve Stenosis, Atrial Fibrillation, Stroke, Systemic Embolism
- Trial name
- ERTEMIS (NCT05540587)
- Testing
- Edoxaban, Warfarin
- Where
- 7 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Sung-Hwan Kim
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke
Effect of Robot Rehabilitation Exercise Training on Motor Control After Stroke
Stroke is a leading cause of neurological disability worldwide, often causing significant weakening and paresis of the affected arm. National spending on post-stroke rehabilitation is project to expand 20% to 35% through 2010.
- Trial name
- NCT02331407
- Testing
- Robotic arm therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Columbia University
Aortic Valve Stenosis, Aortic Stenosis
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
The objective of this study is to demonstrate safety and efficacy of the EmStop Embolic Protection System when used as indicated to capture and remove thrombus/debris during self-expanding transcatheter aortic valve replacement…
- Conditions
- Aortic Valve Stenosis, Aortic Stenosis, Aortic Valve Disease
- Trial name
- NCT07276711
- Testing
- EmStop Embolic Protection System, Boston Scientific Sentinel
- Where
- 7 sites in United States
- Volunteers
- 663 people
- Sponsor
- EmStop Inc
Stroke, Cerebrovascular Accident
Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke
SYNTHESIS is a pragmatic multicenter randomized controlled trial (RCT), open-label, with blinded follow-up aiming to determine whether loco-regional intra-arterial (IA) with recombinant tissue-plasminogen activator (rt-PA) and/or…
- Trial name
- SYNTHESIS EXP (NCT00640367)
- Testing
- Alteplase IA and/or mechanical thrombolysis, Alteplase IV
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Niguarda Hospital
Stroke
Intelligent Cardiopulmonary Rehabilitation System for Patients With Chronic Stroke
By comparing with traditional aerobic exercise training (TAET), we investigate the effects of an intelligent cardiopulmonary rehabilitative system (ICRS) on cardiopulmonary fitness and patient satification among patients with…
- Trial name
- NCT04833400
- Testing
- ICRS, TAET
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Acute Ischemic Stroke, Atrial Fibrillation
Registration Study of Acute Ischemic Stroke/Transient Ischemic Attack (TIA) With Atrial Fibrillation
Patient Registration Study of Acute Ischemic Stroke/transient ischemic attack(TIA) With Atrial Fibrillation (AISWAF) is a single-center prospective, consecutively, observational study, was conducted in patients with acute…
- Trial name
- AISWAF (NCT04080830)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
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