Clinical trials: Apoplexy; Brain
Post-Ischemic Stroke
A Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets.
The objective of this study is to determine the effect of two dose strengths of dalfampridine-Extended Release (ER) tablets, taken twice daily for 12 weeks, on stable walking deficits in subjects with post-ischemic stroke.
- Trial name
- MILESTONE℠ (NCT02271217)
- Testing
- dalfampridine-ER 7.5mg, dalfampridine-ER 10mg
- Where
- 74 sites in United States, Canada
- Volunteers
- 377 people
- Sponsor
- Acorda Therapeutics
Stroke
The General Use of Robots in Stroke Recovery
The purpose of this study is to determine if tailoring multiple sessions of upper extremity robotic therapy to focus on a particular aspect of movement (e.g smoothness vs. aiming; active range of motion vs.
- Trial name
- NCT01726660
- Testing
- IMT Robotic Arm therapy
- Where
- United States
- Sponsor
- Northwell Health
Anosognosia, Stroke
Development of a Novel Screening Tool for Anosognosia After Stroke.
Anosognosia, a neurological inability to acknowledge or comprehend one's own (dis)abilities, is a multi-faceted phenomenon which has consistently gained traction in research fields spanning psychology, neurology, and cognition…
- Trial name
- NCT06940882
- Volunteers
- 90 people
- Sponsor
- University of Exeter
Acute Ischemic Stroke, Atrial Fibrillation
Berlin Atrial Fibrillation Registry
Investigator-initiated prospective multicentre hospital-based registry to uncover the proportion of self-reported anticoagulation in stroke patients with atrial fibrillation and assessing the proportion of stroke, intracranial…
- Trial name
- NCT02306824
- Where
- Germany
- Volunteers
- 1,080 people
- Sponsor
- Charite University, Berlin, Germany
Stroke
Balance Training After Stroke With REWIRE
The study will include 20 patients after stroke, randomly assigned to the experimental and control group (10 each). In both groups, the program with last for five days; walking and balance will be assessed before and after the…
- Trial name
- REWIRESI (NCT03282968)
- Testing
- REWIRE, Balance exercises
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Stroke, Unilateral Spatial Neglect
Immersive Virtual Reality Treatment for Unilateral Spatial Neglect
Unilateral Spatial Neglect (USN) is a relatively common neuropsychological syndrome following stroke. It is characterized by difficulties in detecting, orienting and identifying events located in the hemispace contralateral to a…
- Trial name
- NCT06366360
- Testing
- Immersive Virtual Reality Intervention, Conventional rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hopitaux de Saint-Maurice
Stroke
Stroke Patients Receiving Chiropractic Care Post-rehabilitation
The Life University Center for Chiropractic Research is conducting a research study to better understand how 12-weeks of chiropractic care differentially affects the post-rehabilitation brain electrical patterns and body movement…
- Trial name
- NCT05027178
- Testing
- Chiropractic Care
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Life University
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Hemorrhagic Stroke, Intracerebral, Acute Ischemic Stroke
Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI
The goal is to pilot test a highly accessible, web-based, pragmatic, scalable intervention to overcome ongoing problems with high stakes decision-making by surrogate decision-makers of patients in ICUs with severe acute brain…
- Conditions
- Hemorrhagic Stroke, Intracerebral, Acute Ischemic Stroke, Traumatic Brain Injury
- Trial name
- NCT05671874
- Testing
- Web/mobile/tablet-based digital decision aid + communication (DA+C) tool
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Acquired Brain Injury
Integrated PRocess and StrategieS Training: I-PRESS Training
There is a pressing need to develop more effective interventions to remediate cognitive deficits in highly prevalent disabling conditions such as stroke, head injury and other forms of acquired brain injury (ABI).
- Trial name
- I-PRESS (NCT04882215)
- Testing
- GMT combined with WMU Training
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- NHS Greater Glasgow and Clyde
Dysphagia
Cortical Neuromodulation in Post Stroke Dysphagia
The investigators aim is to try to rehabilitate post stroke dysphagia using electrical stimulation of the mylohyoid muscles.
- Trial name
- NCT01345890
- Testing
- electrical stimulation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Rouen
Ischemic Stroke, Intracerebral Hemorrhage
Registry of Acute Stroke Under Novel Oral Anticoagulants - Prime
The Registry of Acute Stroke Under Novel Oral Anticoagulants-Prime (RASUNOA-Prime), an investigator-initiated study, is a German multicenter, prospective, observational registry.
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Oral Anticoagulation, Cardiovascular Diseases
- Trial name
- RASUNOA-Prime (NCT02533960)
- Testing
- not applicable (observational study)
- Where
- Germany
- Volunteers
- 3,832 people
- Sponsor
- University Hospital Heidelberg
Stroke, Stroke, Ischemic
Bio-Repository of DNA in Stroke: an Epidemiological and Genetic Study
The Bio-Repository of DNA in Stroke (BRAINS) recruits all subtypes of stroke as well as controls from two different continents, Europe and Asia.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- BRAINS (NCT05491824)
- Where
- United Kingdom
- Volunteers
- 7,500 people
- Sponsor
- Royal Holloway University
Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion
Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion
Acute ischemic stroke has a high incidence, ischemic stroke caused by large vessel occlusion is serious and has a poor prognosis, and its triggers in the short term before onset are not clear.
- Trial name
- NCT06265155
- Where
- China
- Volunteers
- 302 people
- Sponsor
- Anzhi Li
Ischemic Stroke
Mesenchymal Stromal Cells for Ischemic Stroke
The purpose of this study is to determine if mesenchymal stem cells given by IV is feasible and safe in patients with recent ischemic stroke and to decide the maximum tolerated dose when given between 3-10 days after an ischemic…
- Trial name
- SAMCIS (NCT01922908)
- Testing
- MSC Infusion
- Sponsor
- Sean Savitz
Stroke
A Study to Evaluate Animal-assisted Therapy in Stroke Rehabilitation
The investigators hypothesize that the presence of a Mayo Clinic certified therapy dog will provide additional benefits above typical treatment for patients currently enrolled in the Mayo Clinic Stroke Rehabilitation Unit.
- Trial name
- NCT05046574
- Testing
- Stroke rehabilitative therapy sessions with therapy dog present
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Stroke
Core Stabilization Exercises in Stroke
A stroke due to a cerebrovascular accident (CVA) is a neurological deficit characterized by the rapid settlement of signs and symptoms due to focal or global loss of cerebral function, without any apparent cause other than…
- Trial name
- NCT05549518
- Testing
- Core stabilization + Traditional Physical Therapy, Traditional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stroke
The Effect of Backward Walking Treadmill Training on Balance in Patient With Chronic Stroke
The purpose of this research was to discuss the effect of backward walking treadmill training on balance ability, speed of walking and cardiopulmonary fitness in patients with chronic stroke.
- Trial name
- NCT02619110
- Testing
- backward walking treadmill training, conventional physical therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
G6PD Deficiency, Stroke
Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST)
Aspirin was reported to induce hemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency on some occasions, while still widely uesd for stroke prevention.
- Trial name
- SAST (NCT04088513)
- Testing
- Aspirin, Clopidogrel
- Where
- 19 sites in China
- Volunteers
- 440 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Stroke
Effect of Robotised Gait Training on Dynamic Balance, Symmetry and Push-off in Persons After Stroke
Rehabilitation robotics is increasingly used because it enables the patients to practice a wide array of movements. Dynamic balance training is essential for gait rehabilitation and robotised devices enhance repeatability…
- Trial name
- BART (NCT03782948)
- Testing
- Standard gait training on BART without pelvic perturbations, Robotised gait training with BART with pelvic perturbations
- Where
- Slovenia
- Volunteers
- 10 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
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