Clinical trials: Appendectomy, Laparoscopic
Appendicitis
Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
To compare surgical site infection (SSI) rate in patients undergoing laparoscopic appendectomy for acute uncomplicated appendicitis and treated with single dose regime of antibiotics versus group of patients undergoing…
- Trial name
- NCT02404064
- Testing
- cefamezin 1g IV, metronidazole 500 mg IV
- Volunteers
- 288 people
- Sponsor
- HaEmek Medical Center, Israel
Appendicitis
Single Incision Versus Conventional Laparoscopic Appendectomy
The aim of this study is to compare the short-term outcomes of single-incision and conventional laparoscopic appendectomy.
- Trial name
- NCT01515293
- Testing
- Single Incision Laparoscopic Appendectomy, Conventional appendectomy
- Volunteers
- 184 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Anesthesia, Analgesia
Use of Intrathecal Analgesia in Appendectomy
Acute appendicitis which is the most common cause of acute abdominal pain, is an acute inflammation of appendix vermiformis. Appendectomy operations can be performed as laparoscopic and open surgery.
- Trial name
- NCT04196946
- Testing
- 25 mcg fentanyl, 250 mcg alfentanil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Gastrointestinal Surgery, Natural Orifice Surgery
IMTN Study- International Prospective Multicenter Trial on Clinical NOTES
Objectives: Since 2007, natural orifice surgery evolved from theory and animal research to clinical applications, but is still limited in the literature to small casuistic reports.
- Trial name
- IMTN (NCT00995735)
- Testing
- Cholecystectomy, Appendectomy
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- IMTN NOTES Research Group
Appendicitis, Laparoscopic
Solo and Non-solo Approach for Laparoscopic Appendectomy (SOLOAP)
To determine the safety and feasibility of solo laparoscopic appendectomy, which is defined as the application of solo surgery to laparoscopic appendectomy, by comparing consecutive non-solo procedures conducted by a surgeon in…
- Trial name
- NCT03224364
- Testing
- nonsolo LA, solo LA
- Volunteers
- 150 people
- Sponsor
- Say-June Kim
Appendicitis
Nebulized Analgesia for Laparoscopic Appendectomy Trial
The objective of this study is to assess whether the administration of nebulized intra-peritoneal ropivacaine at the onset of surgery, compared with nebulized saline, reduces morphine consumption after laparoscopic appendectomy…
- Trial name
- NALA (NCT02624089)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
General Surgery
Outcome of Laparoscopic Appendicectomy Versus Open Appendicectomy in Sudanese Patients
Background: Laparoscopic appendectomy as a minimal invasive procedure had low morbidity and mortality. It affords a direct diagnosis of the problem, allows determination of the appropriate treatment.
- Trial name
- NCT06158308
- Testing
- Laproscopic Appendicectomy, Open Appendicectomy
- Where
- Sudan
- Volunteers
- 340 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Appendicitis (Diagnosis)
Evaluating the Outcome of Surgical Clip Versus Ligatures in Securing Base of Appendix in Laparoscopic Appendicectomy.
The goal of this clinical trial is to evaluate the outcome of using surgical clip versus ligature to secure the base of appendix during laparoscopic appendicectomy.
- Trial name
- OSCVL (NCT07689123)
- Testing
- single polymeric clip (XXL Click'aV Plus, Grena), suture ligature
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- Universiti Sains Malaysia
Appendicitis, Cholelithiasis
Minimally Invasive Surgery: Using Natural Orifice Translumenal Endoscopic Surgery (NOTES)
This is an observational study of pain and outcomes from patients undergoing transgastric NOTES removal of their appendix or gallbladder.
- Trial name
- NOTES (NCT00531219)
- Testing
- Transgastric Appendectomy, Transgastric Cholecystectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Chronic or Recurrent Appendicitis
Laparoscopic Appendectomy for Chronic Right Lower Abdominal Pain
It is questionable whether elective appendectomy can effectively reduce pain in persistent or recurrent lower abdominal quadrant pain due to chronic appendicitis.
- Trial name
- NCT00413855
- Testing
- laparoscopic appendectomy or not (surgery)
- Volunteers
- 40 people
- Sponsor
- Maxima Medical Center
Laparoscopic Surgery, Acute Appendicitis With Rupture
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
- Conditions
- Laparoscopic Surgery, Acute Appendicitis With Rupture, Sepsis, Abdominal Abscess
- Trial name
- reverse (NCT05283733)
- Testing
- reverse conversion technique
- Where
- Egypt
- Volunteers
- 426 people
- Sponsor
- Zagazig University
Appendicitis Acute, Laparoscopic Surgery
Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy
In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip).
- Trial name
- NCT04083313
- Testing
- Technique used for closing the appendiceal stump
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- University Hospital Dubrava
Acute Appendicitis
Laparoscopic Appendectomy by Multi-port vs Single Port.
Laparoscopic appendectomy (LA) is nowadays considered the gold standard in fertile women affected by uncomplicated appendicitis. The level of evidence for benefits from LA in this subgroup is high.
- Trial name
- AMUSING (NCT01720082)
- Testing
- Single incision laparoscopic appendectomy, Multiport laparoscopic appendectomy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Associazione Chirurghi Ospedalieri Italiani
Post Operative Pain, Appendicitis Acute
Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy
Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative…
- Conditions
- Post Operative Pain, Appendicitis Acute, Surgery
- Trial name
- NCT05310266
- Testing
- Transversus abdominis plane block, Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Appendicitis
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
- Trial name
- HASSEL (NCT07049965)
- Testing
- Suture ligation, Harmonic Scalpel
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Acute Appendicitis
The Use of the Hem-o-lok Clip in Appendectomy: Single or Double?
Stump safety is provided by different methods in laparoscopic appendectomy. Stapler use, binding with endoloop and nonabsorbable clip are the most common methods.
- Trial name
- NCT04387370
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ulas Aday
Appendix Rupture, Pain
Virtual Reality for Appendectomy Pain
To determine the impact of VR-Biofeedback and VR-Distraction on pain and medication utilization in children and adolescents undergoing surgery for ruptured appendix.
- Conditions
- Appendix Rupture, Pain, Pain, Postoperative
- Trial name
- NCT04357132
- Testing
- VR-Biofeedback, VR-Distraction
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Appendicitis Perforated, Appendectomy, Laparoscopic
Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis
The ALPACA-MC trial is a blinded, multicentre randomized controlled trial comparing two postoperative antibiotic treatments for children undergoing laparoscopic appendectomy for perforated appendicitis.
- Conditions
- Appendicitis Perforated, Appendectomy, Laparoscopic, Antibiotic, Pediatric
- Trial name
- ALPACA-MC (NCT07869095)
- Testing
- Piperacillin/Tazobactam, Ceftriaxone + Metronidazole
- Volunteers
- 180 people
- Sponsor
- McMaster Children's Hospital
Appendicitis
The Laparoscopic Appendicitis Score; a Multicenter Validation Study
SUMMARY Rationale: A diagnostic laparoscopy is a frequently used method to confirm the diagnosis appendicitis. However until recently evidence-based laparoscopic criteria for determining appendicitis were not defined.
- Trial name
- APPLE (NCT02029781)
- Testing
- LAPP score
- Where
- Netherlands
- Volunteers
- 342 people
- Sponsor
- University Medical Center Groningen
Laparoscopic Appendectomy
Transversus Abdominis Plane Block for Laparoscopic Appendicectomy in Children
The transversus abdominis plane (TAP) block is a regional anesthetic technique for post operative pain control after abdominal surgical procedures.
- Trial name
- NCT02505841
- Testing
- TAP block with Ropivacaine, Curare
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier