Clinical trials: Appetite Disorders
Prediabetes
Effect of Fermentable Carbohydrate on Glucose Homeostasis
The rise in the prevalence of type 2 diabetes is related to recent lifestyle changes leading to a rise in obesity. Obesity is a risk factor for Impaired Glucose Tolerance (IGT) and diabetes.
- Trial name
- FermCarb (NCT01841073)
- Testing
- Inulin, Cellulose
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Imperial College London
Overweight, Obese
The Effect of Protein-enriched Diet on Body Composition and Appetite
Obesity is a major problem worldwide and current dietary interventions are not proving to be enough to cease the increase in levels of obesity and its detrimental side effects, such as nonalcoholic fatty liver disease (NAFLD).
- Conditions
- Overweight, Obese, Metabolic Syndrome, Non Alcoholic Fatty Liver Disease
- Trial name
- ProteinRich (NCT01634048)
- Testing
- High Protein, low calorie meal replacement
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People
The purpose of this study is to examine the effects of normal vs. protein-rich afternoon snacks on appetite control, satiety, and reward-driven eating (particularly in the evening) in young people.
- Trial name
- NCT01781286
- Testing
- High Protein, Low Protein
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Leukemia, Lymphoma
Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With Cancer
RATIONALE: Cyproheptadine hydrochloride may help improve appetite and lessen weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine hydrochloride is more effective with or without nutritional…
- Conditions
- Leukemia, Lymphoma, Malnutrition, Myelodysplastic Syndromes
- Trial name
- NCT00949117
- Testing
- Ensure, PediaSure, cyproheptadine hydrochloride
- Volunteers
- 9 people
- Sponsor
- University of South Florida
Arterial Embolization, Other Surgical Procedures
Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically
The purpose of this pilot study is to achieve the collection of safety and efficacy data in patients undergoing left gastric artery embolization for morbid obesity in the United States.
- Conditions
- Arterial Embolization, Other Surgical Procedures, Obesity
- Trial name
- GETLEAN (NCT02248688)
- Testing
- BeadBlock 300 - 500 Micron, Left Gastric Artery Embolization
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Dayton Interventional Radiology
Overweight, Obesity
The Beneficial Effects of a Protein-rich Breakfast on Appetite Control & Cognition in Overweight and Obese Adolescents
The purpose of this study is to assess whether the daily addition of a protein-rich breakfast leads to beneficial changes in appetite control, food intake regulation,and cognitive function in overweight \& obese 'breakfast…
- Trial name
- NCT01192100
- Testing
- Breakfast Skipping, Normal Protein Breakfast Meals, Protein-rich Breakfast Meals
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Morbid, Insulin Resistance
Stool Transplantation for Treatment of Insulin Resistance in Morbidly Obese Patients
More and more people in Canada and around the world are severely (morbidly) obese, and this is associated with a high risk for poor blood sugar control (insulin resistance, IR) and diabetes.
- Trial name
- NCT02970877
- Testing
- Fecal filtrate from 150 g stool from healthy lean donors, Fecal filtrate from 150 g of the recipient's own stool
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Johane Allard
Obesity, Energy Balance
Activity, Adiposity, and Appetite in Adolescents 2 Intervention
The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents.
- Conditions
- Obesity, Energy Balance, Appetite, Metabolism
- Trial name
- AAAA2INT (NCT05443347)
- Testing
- Aerobic exercise, Newsletter
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Brain Neoplasms, Nausea
A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas
This study seeks to define the tolerability and safety associated with the administration of Dronabinol in the treatment of adults with nausea, vomiting and appetite loss in patients with primary gliomas who are undergoing…
- Conditions
- Brain Neoplasms, Nausea, Vomiting
- Trial name
- NCT00314808
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
Diabetes Mellitus
Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes
Patients with diabetes treated with insulin often gain weight, which may deter patients from adhering to insulin treatment. Detemir is one type of long acting insulin approved by the Food and Drug Administration for use in people…
- Trial name
- NCT00659165
- Testing
- Insulin Detemir, Insulin Glargine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
Obesity
Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
This is a two-phase study. Phase 1 will evaluate obesity-related behavioral and biological characteristics as potential predictors of response to behavioral treatment (BT) for weight loss.
- Trial name
- NCT03779048
- Testing
- Behavioral Treatment, Phentermine 15 MG
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pennsylvania
Pulmonary Disease, Chronic Obstructive (COPD)
Inspiratory Flow Rates Achieved by the COPD Patients Through Breezhaler®, Ellipta® and Handihaler® Inhaler Devices
The purpose of this study was to compare dynamic inspiratory flow rates achieved by a population of Chronic Obstructive Pulmonary Disease (COPD) patients through the Breezhaler®, Ellipta® and Handihaler® dry powder inhaler (DPI)…
- Trial name
- NCT02596009
- Testing
- Breezhaler®, Ellipta®, Handihaler®
- Where
- 5 sites in Argentina
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Gastrointestinal Cancer, Lung Cancer
Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients
The goal of this clinical research study is to evaluate the effectiveness of melatonin for the management of poor appetite and weight loss in advanced cancer patients.
- Trial name
- NCT00513357
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 82 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Overweight
A Study of Tirzepatide in Overweight and Very Overweight Participants
The main purpose of this study is to measure the effect of tirzepatide on food intake in participants who are overweight or very overweight.
- Trial name
- NCT04311411
- Testing
- Tirzepatide, Liraglutide
- Where
- 3 sites in United States
- Volunteers
- 114 people
- Sponsor
- Eli Lilly and Company
Healthy Obesity, Metabolically, Appetite Regulation
Colonic Propionate, Appetite, and Weight Loss
The current protocol aims to investigate the impact of the propionate ester in conjugation with restricted diet on appetite and weight loss.
- Trial name
- ProAp (NCT03322514)
- Testing
- Inulin-Propionate Esters, Inulin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Impaired Glucose Tolerance
The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women
This study will look at the effect of exenatide, a drug which has been approved for the treatment of type 2 diabetes, on body weight, appetite and energy expenditure among moderately obese women without diabetes.
- Trial name
- NCT00456885
- Testing
- exenatide
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Overweight, Obesity
A Short-Term Appetite Suppression Trial Using Appethyl™: The Pizza
The purpose of the study is to determine whether Appethyl™, made from spinach, will reduce appetite and hunger given on the same day of testing.
- Trial name
- Pizza (NCT01919814)
- Testing
- Appethyl™
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Prader-Willi Syndrome
Effects of Exenatide on Overweight Adolescents With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is one of the most common genetic causes of obesity. Obesity is a major source of morbidity and mortality in this population.
- Trial name
- NCT01444898
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Los Angeles
Obesity
Effect of Fibre Products on Appetite and Weight
This study explores the nutritional effects of fibre. Short chain fatty acid(SCFA), such as propionate, are produced through the fermentation of fibre in the bowel.
- Trial name
- NCT00750438
- Testing
- Propionate ester, Inulin, Cellulose
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Weight Loss, Weight Gain
Eating Mindfully to Prevent Weight Regain
The overall objective of this study is to evaluate the efficacy of a mindfulness-based intervention to prevent weight regain in weight-reduced adults.
- Conditions
- Weight Loss, Weight Gain, Eating Behavior, Obesity
- Trial name
- EMPWR (NCT04847843)
- Testing
- Mindfulness Orientated Recovery Enhancement, Control Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah