Clinical trials: Appetite Loss
Aging, Appetite Loss
Effect of a Novel Protein Ingredient Combined With Oral Nutritional Supplement on Appetite in Older Adults
Reduced appetite can occur with ageing and is linked to a higher risk of undernutrition, poorer physical function and becoming frail. Strategies to increase appetite are needed to improve healthy ageing.
- Conditions
- Aging, Appetite Loss, Undernutrition
- Trial name
- NCT06478147
- Testing
- Oral Nutritional Supplement, Oral Nutritional Supplement + Whey Protein Hydrolysate, Whey Protein Hydrolysate + still water
- Where
- Ireland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Anorexia Nervosa, Restricting Type, Anxiety
Anxiety and Reward Interaction and Prediction of Outcomes in Anorexia Nervosa
This study is designed to understand responsiveness to reward in adolescents with restricting-type anorexia nervosa compared with non-clinical controls, and how it is affected by potential-threat perception.
- Trial name
- NCT02948452
- Testing
- fMRI
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy
Degradation of the Anorexic Hormone Peptide YY
Peptide YY (PYY) is a gastrointestinal hormone released from the enteroendocrine cell upon food intake. The N-terminal truncated form, PYY3-36, exerts anorexic effects.
- Trial name
- NCT02493959
- Testing
- PYY1-36 infusion, PYY1-36 + sitagliptin, PYY3-36 infusion
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Healthy, Frailty
Geriatric Anorexia Study 2.0
Reduction in appetite and/or food intake among older individuals is referred to as anorexia of aging (AOA, also known as Geriatric Anorexia).
- Trial name
- GAS2 (NCT05211973)
- Testing
- Wrist Actigraphy Device, Smart Body Weight Scale, Chair Scale
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Boston University
Overweight
Efficacy and Safety of Zenoctil in Reducing Body Weight
The intention of the study is to evaluate the safety and potential body weight and body fat loss effects of a 12-week treatment with Zenoctil in a randomized, double-blind, placebo-controlled, parallel study conducted in…
- Trial name
- NCT01423617
- Testing
- Zenoctil
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)
Biomarkers in EV Associated With Marrow Adiposity in Anorexia
The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa.
- Trial name
- VE_BMAT_AN (NCT06712485)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Obesity, Weight Loss
Impacts of Wild Blueberries on Appetite and Weight Regulation
The objective is to complete a two-phase study to assess how wild blueberries impact regulation of appetite of overweight and obese men and women as well as to determine if wild blueberries can promote more effective weight loss…
- Trial name
- NCT05736432
- Testing
- Blueberries
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Weight Loss
The Leeds Women's Wellbeing (LWW) Study
The purpose of this parallel design study is to assess the relative effects of two 12-week healthy eating dietary interventions: general healthy eating (Diet A) and general healthy eating combined with advice to increase fibre…
- Trial name
- LWW (NCT01539369)
- Testing
- Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Anorexia Nervosa, Anorexia Nervosa Restricting Type
Novel Targetable BIOmarkers in ANorexia NervosA
The overall aim of this present study is to evaluate Growth Differentiation Factor-15 (GDF-15) and inflammatory cytokines as a possible novel and readily treatable target for the successful therapy of Anorexia Nervosa (AN).
- Trial name
- BIOANNA (NCT05885724)
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Anorexia Nervosa
Microbiome Shifts in Adolescent Anorexia Nervosa
The aim of this study is to evaluate the effect of starvation and recovery in adolescent anorexia nervosa patients in regard to microbiome activity and composition and to elucidate potential connections between weight gain…
- Trial name
- MaAN (NCT02962726)
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Eating Disorders
Evaluating the Brain's Response to Natural Versus Artificial Sweetener in Women Who Have Had an Eating Disorder
This study will compare the brain's ability to distinguish between natural and artificial sweeteners in women with and without a history of eating disorders.
- Trial name
- NCT00517335
- Testing
- Functional magnetic resonance imaging (fMRI) scan
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa, Healthy
Homeostatic and Non-homeostatic Processing of Food Cues in Anorexia Nervosa
The goal of the present study is to investigate metabolic gut-brain signaling and the neural correlates of distraction from visual food cues in patients with Anorexia nervosa and healthy controls.
- Trial name
- NCT03075371
- Testing
- Glucose
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Heidelberg Medical Center
Obesity
The Effects of Dairy Products on Energy Balance
The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately…
- Trial name
- MEPEB (NCT01199835)
- Testing
- High Calcium intake from dairy products
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anorexia Nervosa, Healthy Volunteer
Food Intake and IgA Microbiota in Anorexia Nervosa
Anorexia nervosa is characterized by intestinal dysbiosis, related to the feeding behavior impairment presented by these patients.
- Trial name
- AAMIAM (NCT05842343)
- Testing
- Stool sample, Food intake evaluation
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Eating Disorders, Anorexia Nervosa
Serotonin Transporter Concentrations in Women With a History of Anorexia Nervosa
This study will compare the concentrations of serotonin transporter in the brains of women with a history of anorexia nervosa who are currently maintaining a normal weight to those of healthy women of normal weight.
- Trial name
- NCT00320684
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Appetite, Mood
Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss
The primary aims of this study are to assess the effects of habitual dietary protein intakes across the acceptable macronutrient distribution range with lean beef/pork or soy/legumes as the predominate sources of protein on…
- Conditions
- Appetite, Mood, Weight Loss
- Trial name
- NCT01005563
- Testing
- Beef/Pork, Soy/Legumes
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
The Interaction Between Appetite Hormones
Glucagon Like Peptide (GLP) -1 affects metabolic response corrected for weight change
- Trial name
- NCT02094183
- Testing
- GLP-1, low calorie diet
- Where
- 2 sites in Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anorexia Nervosa
Rubber Hand Illusion in Anorexia Nervosa
The present research project aims to verify a possible difference in the recalibration of the real hand position (i.e. proprioceptive drift) in relation to the dimensions of the plastic hand in the Rubber Hand Illusion, among a…
- Trial name
- RHI_size_AN (NCT06296329)
- Testing
- Rubber Hand Illusion
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Anorexia Nervosa
Metabolic Phenotyping in Anorexia Nervosa
After discharge from inpatient treatment, 30-50% of patients with Anorexia Nervosa require re-hospitalization within 4-12 months.
- Trial name
- NCT02087280
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obesity
Inter Individual Variation in Weight Loss Response to Exercise
The identification and characterization of individuals who vary in their response to exercise-induced weight loss is important. Weight loss in response to exercise is variable and it remains unknown who will succeed, why, and…
- Trial name
- NCT00773214
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology