Clinical trials: Appetite and Glucose Responses
Healthy Adult Participants
Effects of an Arabinoxylan-enriched Rusk on Postprandial Glucose, Insulin, Glucagon-like Peptide-1 and Appetite Responses
The aim of the present pilot randomized controlled trial is to compare the effects of the following: 1)-rusk enriched with arabinoxylans (r-rich), 2)-rusk not enriched (r-standard) on blood glucose, insulin values, glucagon like…
- Trial name
- NCT07682857
- Testing
- Enriched rusk, Standard rusk
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Non-Alcoholic Fatty Liver Disease, Total Pancreatectomy
Hepatic Metabolic Changes in Response to Glucagon Infusion
The objective of the study is to investigate how exogenously administered glucagon affects hepatic lipid, glucose and protein metabolism as well as appetite, food intake and resting energy expenditure.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Total Pancreatectomy, Diabetes Mellitus
- Trial name
- NCT03526445
- Testing
- Glucagon, Saline
- Where
- Denmark
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
Overweight, Obesity
Glycaemic Response of Arabic Bread
Bread remains one of the most widely consumed staple foods worldwide, with wheat flour serving as its traditional foundation. However, the widespread dependence on refined wheat-based bread has paralleled the rising prevalence of…
- Conditions
- Overweight, Obesity, Glycaemic Response
- Trial name
- NCT07652320
- Testing
- Control Bread, Chickpea-Enriched Arabic Bread, Pea-Enriched Arabic Bread
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Appetite, Satiety
Effect of Sourdough Bread Consumption on Postprandial Responses, Appetite Regulation and Energy Intake
During this project the effect of yeast bread and sourdough breads consumption on satiety, energy intake at subsequent meal and postprandial metabolic responses, will be investigated.
- Conditions
- Appetite, Satiety, Energy Intake, Glucose Response
- Trial name
- SPAR (NCT06015867)
- Testing
- Dietary Intervention with Wholemeal Bread with Yeast, Dietary Intervention with Wholemeal Sourdough Bread
- Where
- 2 sites in Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cardiovascular Diseases
Effect of Flax, Poppy, Sesame & Salba on Postprandial Blood Glucose Response, Vascular, Appetite & Sensory Parameters
Consumption of whole grains has been heavily endorsed by both government and major health agencies, as evidenced in Health Canada's Food Guide, the US Department of Agriculture's Food Pyramid, and the Heart and Stroke…
- Trial name
- NCT01579656
- Testing
- Salba, Poppy, Flaxseed
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Insulin Sensitivity, Glucose Intolerance
The Effects of Sea Buckthorn and Strawberry on Postprandial Glycaemia, Insulinemia and Appetite
The effects of strawberry and sea buckthorn on postprandial glycaemia and insulinemia as well as on metabolic profiles were examined in overweight or obese male subjects.
- Trial name
- OPUS-WP3C (NCT02412995)
- Testing
- Meal sequence 1-2-3, Meal sequence 1-3-2, Meal sequence 2-3-1
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Potential Abnormality of Glucose Tolerance, Appetite; Lack or Loss, Nonorganic Origin
Short-term Effects of a Carob Snack on Postprandial Glycemic Responses and Energy Intake and Satiety
This study investigated any potential associations between two preloads offered as snacks and postprandial glycemic response, subjective and objective appetite and energy intake in healthy, normal-weight adults.
- Trial name
- NCT02935829
- Testing
- Glucose as reference food, White bread as reference food, Carob snack as test food
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Malnutrition; Diabetes, Malnutrition; Protein
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid release in healthy adults.
- Conditions
- Malnutrition; Diabetes, Malnutrition; Protein, Obesity
- Trial name
- PLO (NCT05291351)
- Testing
- Crackers made with whole, coarse, or fine pea and/or wheat flour, Crackers made with whole, coarse, or fine lentil and/or wheat flour, Porridge made with oat flour
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Postprandial Hyperglycemia
Bread Structure and Postprandial Metabolic Responses
The structural properties of bread are considered one of the most important factors that can affect its digestibility, glucose homeostasis and postprandial metabolic responses.
- Trial name
- NCT05691686
- Testing
- Finely milled whole wheat-legume bread, Less processed whole wheat-legume bread, Less processed whole wheat bread
- Where
- Greece
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Food Selection
Satiety Effects of the Combination of Egg and Whole Grains
The satiety effects of the combination of protein and fiber within egg and whole grain breakfast meals. High protein with low and high-fiber is hypothesized to be more satiating than low protein, low fiber.
- Trial name
- NCT02272153
- Testing
- Egg refined grain, Egg Whole Grain, Cereal Refined grain
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Glycemic Control, Satiety Response
Postprandial Glycemia and Satiety of Meals With Potatoes, With and Without Protein
The proposed study aims to simulate a meal eaten at home, where meals will provide a fixed amount of protein from beef or vegetarian substitute "meat" balls with ad libitum access to one of mashed potatoes, full-fat fries, or…
- Conditions
- Glycemic Control, Satiety Response, Appetite Regulation, Diabetes
- Trial name
- NCT05610124
- Testing
- Ad libitum full-fat French fries with beef meatballs, Ad libitum instant mashed potatoes with beef meatballs, Ad libitum macaroni pasta with beef meatballs
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
High Blood Glucose
Brown Seaweeds Effect on Glucose Tolerance and Appetite Response
The project is a randomized, 3-way, blinded crossover trial in which 20 healthy, fasted participants consume meals with 30 g of a linear corn starch and 5 g of one of the seaweeds, Laminara digitata or Undaria pinnatifida or a…
- Trial name
- NCT02608372
- Testing
- LD, UP, CTR
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00980941
- Testing
- soup with or without starch
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Glucose Metabolism Disorders
Effects of Sucralose on Glucose Metabolism
In this study the effects of sucralose on insulin sensitivity, beta-cell response and appetite regulating hormones will be evaluated.
- Trial name
- Sucralose (NCT02589002)
- Testing
- Sucralose
- Where
- Mexico
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Diabetes Prevention, Obesity Prevention
Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y.
- Trial name
- NCT02147496
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes Mellitus
Peanuts Second Meal Glycemic Response
Nut consumption is associated with reduced risk of Type 2 diabetes. The aim of this study was to assess the effects of peanut (whole or peanut butter) to breakfast meals on glycemic, insulinemic and selected gut hormone…
- Trial name
- NCT01413126
- Testing
- Whole peanuts without skins, Peanut butter, or no peanuts (control)
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Federal University of Vicosa
The Focus of the Study is Healthy Volunteers
Appetite Regulation by a Breakfast Soft Bread
The aim of this study is to evaluate the appetite rating of a soft bread with a high content of fibre and protein (Puravita Breakfast®) as well as its capacity to modulate postprandial levels of glucose, insulin and…
- Trial name
- NCT02090049
- Testing
- Puravita Breakfast, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Puratos
Obesity, Hyperglycemia
A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
The objective of the current study is to determine the effects of an ad libitum intake of 1% milk, fruit juice, regular cola, diet cola and water, as part of a pizza meal, on meal food intake, appetite and postprandial blood…
- Trial name
- NCT01595919
- Testing
- Nutritional Intervention
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Type II Diabetes Mellitus
Yellow Pea Fractions and Short-term Food Intake, Subjective Appetite and Glycemic Response
It is hypothesized that yellow pea protein and fiber will reduce short-term food intake, subjective appetite and glycemic response.
- Conditions
- Obesity, Type II Diabetes Mellitus, Metabolic Syndrome
- Trial name
- NCT01242059
- Testing
- yellow pea protein, yellow pea fiber, Control
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto