Clinical trials: Approach-Approach Conflict
Rectal Cancer Surgery
Comparison of Different Surgical Approaches in Female Rectal Cancer.
Mid-to-low rectal cancer exhibits an extremely high incidence rate in China. Currently, the primary treatment approach for mid-to-low rectal cancer remains surgical intervention, with total mesorectal excision (TME) being the…
- Trial name
- NCT07189780
- Testing
- Surgical approach
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Maxillary Sinus Disease
Efficacy of Piezosurgery Versus Conventional Osteotomy in Prelacrimal Approach Targeting Different Maxillary Sinus Pathologies
The prelacrimal recess approach is a minimally invasive approach to maxillary sinus lesions. The current study aimed to evaluate the efficacy of piezosurgery versus conventional osteotomy while performing a prelacrimal apporach.
- Trial name
- prelacrimal (NCT07332585)
- Testing
- piezo-assisted prelacrimal apporach, conventional osteotomy prelacrimal approach
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Social Anxiety Disorder, Generalized Anxiety Disorder
Where We All Meet: ACT Approach to Adolescents Anxiety Disorders
Transdiagnostic approaches have been proposed as more truthfully representing mental health problems. Acceptance and Commitment Therapy (ACT) is a transdiagnostic approach that proposes Psychological Inflexibility/Flexibility…
- Trial name
- NCT05906849
- Testing
- ACT for anxiety disorders
- Where
- Portugal
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Mycobacterium Avium-intracellulare Infection, HIV Infections
Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS
To compare the safety and efficacy of two doses of clarithromycin in combination with ethambutol and either rifabutin or clofazimine for the treatment of disseminated Mycobacterium avium Complex (MAC) disease in AIDS patients.
- Trial name
- NCT00001047
- Testing
- Ethambutol hydrochloride, Clarithromycin, Clofazimine
- Where
- 16 sites in United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Schistosomiasis, Schistosoma Mansoni
Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis
The goal of this clinical trial is to learn if treating individuals living in Uganda who have liver fibrosis (scarring) due to schistosomiasis would benefit from more frequent treatment with drug praziquantel.
- Conditions
- Schistosomiasis, Schistosoma Mansoni, Liver Fibrosis, Portal Hypertension
- Trial name
- SchiFT (NCT07754617)
- Testing
- Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year
- Where
- Uganda
- Volunteers
- 600 people
- Sponsor
- Rhode Island Hospital
Melasma
Different Dermatological Approaches the Treatment of Melasma
To compare the efficacy and safety of cryopeeling (using Liquid Nitrogen) and tranexemic acid (cyclokapron) versus chemical peeling (using TCA 20%) in treatment of melasma.
- Trial name
- NCT03923062
- Testing
- chemicalpeeling, cryopeeling, microneedling
- Volunteers
- 40 people
- Sponsor
- Assiut University
Acute Decompensated Heart Failure
REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure
The purpose of this study is to determine whether in patients with acute decompensated congestive heart failure and the cardiorenal syndrome, i.e.
- Trial name
- REWORD-HF (NCT01140399)
- Testing
- Furosemide or Furosemide and Dopamine, Ultrafiltration
- Where
- 16 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Niguarda Hospital
Risk of Breast Cancer, Risk of Gynaecological Cancer
Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals
LEAH is a prospective, observational, single-centre, non-randomised, open-label study of people at increased risk of cancer or malignant disease.
- Conditions
- Risk of Breast Cancer, Risk of Gynaecological Cancer, Risk of Colorectal Cancer, Risk of Upper Gastrointestinal Cancers
- Trial name
- LEAH (NCT06907095)
- Testing
- biological samples
- Where
- France
- Volunteers
- 5,909 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma
Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function
Brachial plexus blocks used for anesthesia in upper extremity operations can be performed with interscalene, axillary, supraclavicular and infraclavicular approaches.
- Conditions
- Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma, Complications, Respiratory Complication
- Trial name
- NCT04756050
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Prilocaine HCl % 2 injectable solution, adrenaline amp 0.5mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Mild Cognitive Impairment (MCI), Geriatric
Investigation of Different Rehabilitation Approaches in Older Adults With Mild Cognitive Impairment
This randomized controlled trial aims to comparatively examine whether cognitive training and hand exercise training provided to older adults with mild cognitive impairment (MCI) have an impact on their cognitive functions, hand…
- Trial name
- NCT06837493
- Testing
- Resistance based hand exercises and functional task-oriented hand exercise, Cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Uşak University
Involutional Ptosis
Comparison Between Different Surgical Approaches for the Treatment of INVOLUTIONAL PTOSIS
Involutional ptosis is a known eyelid pathology in which the eyelid margin obscures part of the visual axis (MRD1).Patients usually complains of visual field disturbance, deterioration in quality of life and a poor cosmetic…
- Trial name
- NCT03373812
- Testing
- Blepharoptosis repair
- Volunteers
- 120 people
- Sponsor
- Meir Medical Center
Shallow Vestibular Depth, Gingival Recession
The Relationship Between Root Coverage Procedures and Buccal Vestibular Depth
In this comparative trial, 50 patients with shallow vestibules and Type 1/2 recessions will be treated with either a vertically coronally advanced flap + connective tissue graft or a free gingival graft.
- Trial name
- NCT05777811
- Testing
- Vertically coronally advanced flap combined with connective tissue graft., Free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Non-specific Neck Pain
Effects of Physiotherapy Approaches on Biopsychosocial Outcomes in Chronic Non-Specific Neck Pain
Chronic non-specific neck pain (CNSNP) is a widespread musculoskeletal condition leading to pain, disability, and impaired quality of life.
- Trial name
- NCT07784504
- Testing
- Structured Exercise Program, Sensorimotor Training, Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medipol University Hospital
Alveolar Ridge Resorption
Different Approaches for Alveolar Ridge Preservation
Following tooth extraction, physiologic remodeling of the alveolar ridge results in significant horizontal and vertical bone resorption, often accompanied by soft tissue collapse.
- Trial name
- NCT07818447
- Testing
- Bone Allograft + Autologous Platelet-Rich Fibrin (PRF) Membrane, Control group, Bone Allograft + Resorbable Guided Bone Regeneration Membrane
- Where
- Greece
- Volunteers
- 51 people
- Sponsor
- Danae A. Apatzidou
Neck Pain Musculoskeletal
Comparison of Different Rehabilitation Approaches in Chronic Neck Pain
Chronic neck pain is a common musculoskeletal disorder that negatively affects daily life and quality of life. Exercise and manual therapy are widely used treatment strategies, but there is limited evidence comparing different…
- Trial name
- NCT07169084
- Testing
- Manual Therapy, Instrument-Assisted Soft Tissue Mobilization (IASTM)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Atlas University
Gingival Recession
Two Surgical Approaches for Root Coverage of Teeth Presenting Gingival Recession and Non-carious Cervical Lesion
The aim of the present study is to compare the use of the xenogeneic graft (MC) plus coronary advanced flap (CAF) and the coronary advanced flap alone, both associated with the partial restoration of composite resin in the…
- Trial name
- NCT03341598
- Testing
- CAF, R, MC
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Smoking Cigarette, Smoking Behaviors
Vape Use Among Younger & Older Smokers
The study aims to recruit 100 current cigarette smokers (50 young adults ages 21-34; 50 older adults ages 35-65) who have tried vaping or are currently vaping (dual users).
- Conditions
- Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors
- Trial name
- ENDS (NCT07214168)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Class II Division 1 Malocclusion
Distalization Via Skeletally-anchored Distaljet Appliance With Two Approaches of Micro-osteoperforations
study will be directed to evaluate two approaches of micro-osteoperforations during maxillary molar distalization.
- Trial name
- NCT05171738
- Testing
- skeletally anchored distal jet
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital