Clinical trials: Approach-Approach Conflict, open to volunteers
Prostate Cancer
Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer
In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with…
- Trial name
- NCT07548164
- Testing
- NanoKnife System, Stereotactic Body Radiation Therapy
- Where
- 8 sites in United States
- Volunteers
- 224 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Chronic Non-specific Neck Pain
Effects of Physiotherapy Approaches on Biopsychosocial Outcomes in Chronic Non-Specific Neck Pain
Chronic non-specific neck pain (CNSNP) is a widespread musculoskeletal condition leading to pain, disability, and impaired quality of life.
- Trial name
- NCT07784504
- Testing
- Structured Exercise Program, Sensorimotor Training, Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medipol University Hospital
Pelvic Floor Disorder
Differential Rehabilitative Treatment for Pelvic Floor in Sportswoman
In this study at least 24 sportswoman (18-50 years old) will be recruited a randomized in two groups which will be differently treated for the following 8 weeks.
- Trial name
- DiRehFloor (NCT06914791)
- Testing
- Kegel arm, De Gasquet arm
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alessandro Micarelli
Ischemic Stroke, TIA
Determining the MCID for the TOPICS-SF and PROMIS-10 in Older Patients That Suffered an Ischemic Stroke or TIA
Patient-related outcome measures (PROMs) play a crucial role in assessing patient outcomes in healthcare. Two of these PROMs are the The Older Persons and Informal Caregivers Survey Short Form (TOPICS-SF) and Patient-Reported…
- Trial name
- CONSIDER (NCT06495073)
- Testing
- PROMIS-10 and TOPICS-SF
- Where
- 2 sites in Netherlands
- Volunteers
- 125 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Transgender, Gut Microbiome
Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach
The XCVD study investigates the influence of sex hormones on the composition of the gut microbiome and the possible emergence of cardiovascular risk factors.
- Conditions
- Transgender, Gut Microbiome, Immune System, Cardiovascular Risk Factors
- Trial name
- XCVD (NCT05334888)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Neck Pain
Physiotherapy in Chronic Neck Pain
In this randomized controlled experimental study design, it was aimed to examine whether different treatment approaches frequently applied in physical therapy clinics have an effect on pain, hand grip strength and hand skills by…
- Trial name
- NCT06957639
- Testing
- Standard physiotherapy intervention and home exercises, Trigger point therapy and home exercises, Kinesiology Taping therapy and home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Uşak University
Turner Syndrome
A Study Comparing Different Treatment Approaches for the Initiation of Puberty in Girls With Turner Syndrome Using a TRIFECTA-DARED Approach for Rare Diseases
Turner syndrome is a condition in which a girl's body does not make enough estrogen on its own, so doctors give estrogen to help start breast and uterine (womb) development.
- Trial name
- TRIFECTA-DARED (NCT07041814)
- Testing
- Oral estradiol valerate, Transdermal 17β estradiol
- Where
- Malaysia
- Volunteers
- 24 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Oesophageal Cancer
Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy
Oesophagectomy (surgery to remove a cancerous portion of the oesophagus or gullet) is the cornerstone of treating oesophageal cancer.
- Trial name
- NCT06965205
- Testing
- MCT feeding, Standard feeds
- Volunteers
- 160 people
- Sponsor
- Royal College of Surgeons, Ireland
Depression
Comparison of Targeting Methods for Transcranial Magnetic Stimulation Treatment of Depression
We aim to learn whether use of a mixed reality device for transcranial magnetic stimulation (TMS) targeting can improve treatment outcomes compared to targeting through scalp measurements or a commercial neuronavigation system.
- Trial name
- XRnav (NCT04730180)
- Testing
- Transcranial Magnetic Simulation, Mixed reality neuronavigation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction
The incidence of esophagogastric junction has been increasing in recent years, and surgery is an important method for the treatment of adenoma at the esophagogastric junction.
- Trial name
- NCT05356520
- Testing
- Endoscopy Ivor-lewis, Laparoscopic transabdominal enlarged gastrectomy
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Variation of Keratinized Mucosa After Implant Surgery
Keratized Mucosa in CG Implant Placement: CTG vs Flapless
The present study will evaluate the difference in terms of keratinazed mucosa (KM) in computer guided implant placement with immediate loading, comparing a flapless approach to flap surgery with connective tissue graft.
- Trial name
- NCT05073952
- Testing
- Connective tissue graft, Flapless
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Milan
Thoracic Surgery, Video-assisted
Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Op Pain Management After VATS Lung Resection
Video-assisted thoracoscopic lung resection (VATS) is a minimally invasive surgical approach frequently used in the treatment of lung cancers.
- Conditions
- Thoracic Surgery, Video-assisted, Paravertebral Block
- Trial name
- NCT07063602
- Testing
- Evaluation of the hypoesthesia of the thorax
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Rectal Cancer Surgery
Comparison of Different Surgical Approaches in Female Rectal Cancer.
Mid-to-low rectal cancer exhibits an extremely high incidence rate in China. Currently, the primary treatment approach for mid-to-low rectal cancer remains surgical intervention, with total mesorectal excision (TME) being the…
- Trial name
- NCT07189780
- Testing
- Surgical approach
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Carpal Tunnel Syndrome
Different Treatment Approaches for Carpal Tunnel Syndrome
Carpal tunnel syndrome is a common syndrome in the upper extremities resulting from compression of the median nerve, which branches out to the first three fingers of the wrist.
- Trial name
- NCT07048379
- Testing
- Orthosis, Physical Therapy
- Volunteers
- 51 people
- Sponsor
- Sakarya University
Extubation Readiness, Respiratory Failure With Hypoxia
Identifying the Best Flow Setting Strategy for High-Flow Nasal Cannula
The goal of this randomized trial is to compare four different flow-setting approaches for post-extubation use of high-flow nasal cannula (HFNC).
- Trial name
- NCT07007715
- Testing
- Flow of 40L/min, Peak tidal inspiratory flow (PTIF) guided, PaO2/FiO2 ratio guided
- Where
- Taiwan
- Volunteers
- 480 people
- Sponsor
- National Taiwan University Hospital
Aggression, Critical Care Staff
Intensive Care Unit Conflict Mediation Study
To evaluate the impact of a structured, multidisciplinary conflict management program incorporating an interprofessional Singular Care Plan *PAS* Committee and a Conflict Mediation Team on the incidence and severity of conflicts…
- Conditions
- Aggression, Critical Care Staff, Workplace Violence
- Trial name
- "GIRAFFE" (NCT07621874)
- Testing
- SEM DESTINO
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Time
Perioperative Analgesic Effect of Different Volumes of Modified Thoracoabdominal Perichondrial Approach on Patients Undergoing Sleeve Gastrectomy: Prospective Randomized Trial
Sleeve gastrectomy is a leading technique in metabolic \& bariatric surgery. It gained ever-increasing popularity among laparoscopic bariatric surgeries and has proved to be a successful method in achieving considerable weight…
- Trial name
- NCT07510347
- Testing
- Modified Thoracoabdominal Nerve Block through perichondrial approach (M-TAPA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Sports Physical Therapy, Tendinopathy
The Effectiveness of Different Exercise Approaches in Biceps Brachii Long Head Tendinopathy
This study was planned to analyze the changes in tendon cross-sectional area and shoulder pain with different exercise approaches applied in biceps brachii long head tendinopathy.
- Trial name
- NCT07025668
- Testing
- Eccentric Exercise, Combined Exercise, Control Group Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Bladder Cancer
TReatment Approaches and bIomarkers preValence in bladdEr Cancer in RuSsian Federation
A multicentre observational study on treatment approaches and HER2 positive status prevalence in different stages of bladder cancer and PD-L1-positive status in metastatic bladder cancer in Russian Federation
- Trial name
- RIVERS (NCT07038928)
- Where
- 20 sites in Russia
- Volunteers
- 600 people
- Sponsor
- AstraZeneca