Clinical trials: Arrhythmia Atrial
Atrial Fibrillation, Left Atrial Appendage Closure
Registry on Luma Vision's VERAFEYE System (ENLIgHT)
The objective of the study is to compile real-world data on the use of the VERAFEYE System in standard of care atrial fibrillation (AF) ablation procedures and left atrial appendage closure (LAAC) procedures.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Atrial Arrhythmia
- Trial name
- ENLIgHT (NCT06293430)
- Testing
- VERAFEYE System
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Arrhythmia, Cardiomyopathy
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are: I.
- Conditions
- Arrhythmia, Cardiomyopathy, Arrhythmia-induced Cardiomyopathy (AiCM)
- Trial name
- UNCHAINED-I (NCT06896266)
- Where
- 4 sites in Spain
- Volunteers
- 109 people
- Sponsor
- Hospital Universitario 12 de Octubre
Atrial Fibrillation, Atrial Flutter
Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures
The objective of the study is to collect data on the usability and integration of the VERAFEYE Imaging and Guidance System in adult patients indicated to undergo a standard of care catheter-based ablation procedure for the…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- INSiGHT (NCT07271238)
- Testing
- VERAFEYE Imaging and Guidance System
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Arrhythmias, Cardiac
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.
- Trial name
- NCT00921986
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
4-electrode Tablet-based Electrocardiogram (ECG) System, Electrical Activity of the Heart
4-electrode ECG (DigitalCardio®) vs Standard 10-electrode ECG: Evaluating Ease of Use and Recording Quality
The goal of this clinical trial is to compare the time required to record a complete Electrocardiogram (ECG) trace using the DigitalCardio (CardioSecur®) tablet device versus a standard 12-lead ECG device in eligible patients.
- Conditions
- 4-electrode Tablet-based Electrocardiogram (ECG) System, Electrical Activity of the Heart, Atrial or Ventricular Arrhythmias, Intracardiac Conduction Abnormalities
- Trial name
- FAST-ECG (NCT07732283)
- Testing
- standard 10-electrode ECG acquisition, 4-electrode DigitalCardio acquisition
- Where
- 2 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Arrhythmia, Cardiomyopathy, Dilated
RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases
Arrhythmias are widespread among the global population. Although they can occur in healthy hearts, they are often the manifestation of a hereditary or acquired heart muscle disease, and may be the cause or, more often than not…
- Conditions
- Arrhythmia, Cardiomyopathy, Dilated, Systolic Dysfunction, Atrial Fibrillation
- Trial name
- RHYME-HD (NCT07491237)
- Testing
- speckle tracking echocardiography
- Where
- Italy
- Volunteers
- 253 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Patent Foramen Ovale, Atrial Arrhythmia
Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia
About 30% of ischemic strokes are cryptogenic. Patent Foramen Ovale (PFO) is present in about 25% of the general population. In cryptogenic strokes, PFO has been shown to be overrepresented and recent intervention studies have…
- Conditions
- Patent Foramen Ovale, Atrial Arrhythmia, Cryptogenic Stroke
- Trial name
- AFLOAT (NCT05213104)
- Testing
- Flecainide
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
This is a prospective multicenter clinical study comparing the efficacy of the Apple Watch AFib History tool to the iRhythm Zio Patch monitoring device in quantifying atrial fibrillation (AF) burden after surgical ablation.
- Trial name
- STARBURST-AF (NCT07122947)
- Testing
- Apple Watch: AFib History, Zio Patch
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Atrial Fibrillation (AF), Arrhythmia
Computed Tomography of Pulse-Field Ablation
Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) reduces left atrial (LA) volume post-ablation, a phenomenon termed reverse atrial remodeling, indicative of successful reversal of atrial cardiomyopathy…
- Trial name
- CT-PFA (NCT07395089)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Pulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF
Being the most common arrhythmia, atrial fibrillation (AF) is a high burden of public health with an increasing prevalence in our aging population.
- Trial name
- PVI-SHAM-AF (NCT05119231)
- Testing
- Pulmonary Vein Isolation
- Where
- 9 sites in Germany, Poland
- Volunteers
- 262 people
- Sponsor
- University of Leipzig
Acute Heart Failure (AHF), Cardiac Arrhythmia
Arrhythmia Detection With MEMO Patch Plus in Patients With Acute Heart Failure
This prospective, multicenter, open-label, single-group exploratory clinical trial evaluates the clinical effectiveness of extended electrocardiographic monitoring with MEMO Patch Plus for detecting clinically significant…
- Trial name
- MMPP-HF (NCT07792772)
- Testing
- MEMO Patch Plus
- Where
- 3 sites in South Korea
- Volunteers
- 45 people
- Sponsor
- HUINNO Co., Ltd
Atrial Fibrillation, Arrhythmias, Cardiac
Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Atrial fibrillation (AF) affects 1 in 4 individuals during their lifetime and continues to increase in frequency and impact. Exercise intervention has established benefits to improve AF symptoms and burden in clinical studies.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- EASE-AF (NCT06938412)
- Testing
- Physical Activity Intervention Using FitBit Wearable Device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Atrial Fibrillation, Cardiovascular Diseases
NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial
The goal of this clinical trial is to determine if a machine learning/artificial intelligence (AI)-based electrocardiogram (ECG) algorithm (rECHOmmend and ECG-AF) can identify undiagnosed cardiovascular disease in patients.
- Conditions
- Atrial Fibrillation, Cardiovascular Diseases, Arrhythmia, Valvular Disease
- Trial name
- NOTABLE (NCT06511505)
- Testing
- Risk-Based Assessment for Cardiac Dysfunction
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atrial Fibrillation, Persistent, Arrhythmias, Cardiac
Using Cryoballoon Ablation as Initial Treatment for Persistent Atrial Fibrillation
This study is to assess the effectiveness and safety of using cryoballoon ablation comparing with anti-arrhythmic drug therapy as initial treatment for naive patients with persistent atrial fibrillation.
- Trial name
- Cryo-InitialAF (NCT04942834)
- Testing
- Antiarrhythmic drug including Propafenone, Sotalol, Dronedarone and Amiodarone, cryoballoon ablation
- Where
- 17 sites in China
- Volunteers
- 320 people
- Sponsor
- Ruijin Hospital
Heart Diseases, Arrhythmias, Cardiac
Testing VIRTUES Patient Care Sets in Cardiac Patients (VIRTUES Cardiac Care)
Patients with various cardiac conditions (such as those who experience a heart attack) are increasing in Canada and are in need of appropriate cardiac rehabilitation and care.
- Conditions
- Heart Diseases, Arrhythmias, Cardiac, Atrial Fibrillation, Cardiovascular Diseases
- Trial name
- VIRTUES-CC (NCT05452356)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Atrial Fibrillation, Post-Catheter Ablation Atrial Arrhythmia Recurrence
Ezetimibe for Arrhythmia Recurrence After AF Ablation
This single-center, prospective, single-blind randomized controlled pilot trial aims to explore whether oral ezetimibe can reduce the 6-month recurrence rate of atrial tachyarrhythmia after catheter ablation in patients with…
- Trial name
- EAFA (NCT07752758)
- Testing
- Ezetimibe, Standardized post-ablation clinical management
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atrial Arrhythmia, Atrial Fibrillation
VOLT-AF IDE Clinical Study
This clinical investigation is intended to demonstrate safety and effectiveness of the Volt™ Pulsed Field Ablation (PFA) Catheter Sensor Enabled™, the Volt™ PFA Generator, Agilis™ NxT Steerable Introducer Dual-Reach™, and EnSite™…
- Conditions
- Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
- Trial name
- NCT06223789
- Testing
- Pulsed Field Ablation
- Where
- 40 sites in United States, Australia and 9 more
- Volunteers
- 392 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation
Ground-Breaking Electroporation-based Intervention for PAROXysmal Atrial Fibrillation Treatment (BEAT PAROX-AF)
BEAT AF is a randomized controlled trial aiming to demonstrate that pulsed field energy is faster, more effective and safer (tissue selectivity) than RF for paroxysmal AF ablation
- Trial name
- BEAT PAROX-AF (NCT05159492)
- Testing
- PVI using PEF, PVI using CFRF
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 292 people
- Sponsor
- University Hospital, Bordeaux
Premature Atrial Contractions, Premature Ventricular Contractions
The MARY-JANE Cannabis and Heart Rhythm Trial
Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited.
- Trial name
- NCT06021613
- Testing
- Randomized instructions
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco