Clinical trials: Arrhythmia Ventricular
Ventricular Arrythmia
Risk Stratification Value of Biomarkers in Patients With Ventricular Arrhythmias
The investigation of biomarkers for immune status and metabolic state, as well as host microbiota composition, in patients with ventricular arrhythmias before and after radiofrequency ablation, can provide new insights for…
- Trial name
- FUTURE (NCT05965375)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Atrial Fibrillation, Atrial Flutter
Risk Factors in Tachycardiomyopathy
Decision between rate control and rhythm control can be a challenge in clinical practice. While there is some guiding evidence, we still lack a comprehensive insight into different subgroups of patients that will benefit from a…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Ventricular Premature Complexes
- Trial name
- EMPATHY (NCT03418467)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Ventricular Fibrillation, Ventricular Tachycardia
SD01 Registry (SD01 ICD Lead)
This registry is designed to gather further evidence, in addition to the SD01 Master Study, for the safety and efficacy of the SD01 ICD lead.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Heart Failure
- Trial name
- SD01 Registry (NCT02014675)
- Testing
- SD01 ICD lead
- Where
- 10 sites in Germany
- Volunteers
- 280 people
- Sponsor
- Biotronik SE & Co. KG
Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA)
Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest
The aim of the study is to investigate whether occluding the abdominal aorta with an external device could be a potential therapeutic option in cases of non-traumatic cardiac arrest occurring outside of a hospital.
- Conditions
- Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA), Asystole, Pulseless Electrical Activity
- Trial name
- ATTICA (NCT07573566)
- Testing
- Abdominal Aortic Junction Tourniquet in non-traumatic out-of-hospital cardiac arrest
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Ventricular Tachycardia
Preventive aBlation of vEntricular tachycaRdia in Patients With myocardiaL INfarction
The BERLIN VT study is designed to evaluate the impact of prophylactic ventricular tachycardia (VT) ablation on all-cause mortality and unplanned hospital admission for congestive heart failure or symptomatic ventricular…
- Trial name
- BERLIN VT (NCT02501005)
- Testing
- VT ablation
- Where
- 5 sites in Germany
- Volunteers
- 163 people
- Sponsor
- Biotronik SE & Co. KG
Arrhythmias, Cardiac, Tachycardia, Ventricular
International Electrical Storm Registry
Organized ventricular arrhythmias (ventricular tachycardia (VT), torsades de pointes (TdP) and ventricular fibrillation (VF)) represent a major event in the clinical history of a patient and they can lead to hemodynamic…
- Conditions
- Arrhythmias, Cardiac, Tachycardia, Ventricular, Ventricular Fibrillation, Defibrillators, Implantable
- Trial name
- ELECTRA (NCT02882139)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Università Politecnica delle Marche
Tachycardia, Ventricular Arrythmia
Extravascular ICD Pivotal Study
Pivotal Summary: The study is designed to demonstrate safety and efficacy of the Extravascular Implantable Cardioverter Defibrillator (EV ICD) System.
- Trial name
- EV ICD (NCT04060680)
- Testing
- Defibrillation using the Extravascular ICD
- Where
- 56 sites in United States, Australia and 15 more
- Volunteers
- 393 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Aortic Stenosis, Transcatheter Aortic Valve Replacement
Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System
This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement.
- Conditions
- Aortic Stenosis, Transcatheter Aortic Valve Replacement, Heart Block
- Trial name
- TAVR-HBE (NCT04982406)
- Testing
- Transcatheter aortic valve replacement
- Where
- United States
- Volunteers
- 409 people
- Sponsor
- Beth Israel Deaconess Medical Center
Ventricular Tachycardia, Atrial Fibrillation
AVAI: Atrial Ventricular Arrythmia Incidence
The purpose of this observational study is to collect data regarding the population of patients implanted with St. Jude Medical ICD.
- Trial name
- AVAI (NCT00832975)
- Where
- 2 sites in Spain
- Volunteers
- 157 people
- Sponsor
- Abbott Medical Devices
Persistent Atrial Fibrillation, Atrial Fibrillation, Persistent
Hybrid Ablation of Atrial Fibrillation in Heart Failure
A randomised controlled trial to assess the efficacy of staged hybrid ablation when compared with standard catheter ablation in patients with non-paroxysmal atrial fibrillation (AF) and Heart Failure
- Conditions
- Persistent Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Arrhythmia, Atrial Fibrillation
- Trial name
- HALT AF (NCT05411614)
- Testing
- AtriCure EPi-Sense-AF Guided Coagulation System +/- Atriclip, Endocardial Catheter Ablation
- Where
- 7 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- St. George's Hospital, London
Arrhythmogenic Cardiomyopathy, PKP2-ACM
Gene Therapy for ACM Due to a PKP2 Pathogenic Variant
This is a Phase 1/2, first-in-human, open-label, intravenous, dose-escalating, multicenter trial that is designed to assess the safety and tolerability of LX2020 in adult patients with PKP2-ACM
- Conditions
- Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
- Trial name
- NCT06109181
- Testing
- LX2020
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Lexeo Therapeutics
Myocardiopathies, Ischemia, Myocardial
Extracellular Matrix Marker of Arrhythmia Risk (EMMA)
Assess whether serum levels of MMP 2 and or MMP 9 correlate with episodes of ventricular tachycardia or fibrillation in patients who have implantable cardioverter defibrillator devices.
- Conditions
- Myocardiopathies, Ischemia, Myocardial, Arrythmia, Death, Sudden, Cardiac
- Trial name
- EMMA (NCT00376532)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Thomas Jefferson University
Death, Sudden, Cardiac, Ventricular Fibrillation
DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.
To prospectively evaluate if the analysis of genetic polymorphisms can be used to identify patients at risk of ventricular tachycardia.
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation
- Trial name
- DISCOVERY (NCT00478933)
- Testing
- Defibrillator, Dual Chamber ; Implantable, Blood sampling
- Volunteers
- 1,223 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ventricular Tachycardia, Ventricular Flutter
Feature Assessment Study for Indications Based Programming
The purpose of this evaluation is to assess the acceptance level of specific programming recommendations based on the patient's clinical needs and primary indications when using the feature 'Indications Based Programming' (IBP)…
- Conditions
- Ventricular Tachycardia, Ventricular Flutter, Ventricular Fibrillation, Heart Failure
- Trial name
- FASt-IBP (NCT00711893)
- Testing
- Cognis 100-D, Teligen DR and VR 100 HE
- Where
- 28 sites in Austria, Belgium and 9 more
- Volunteers
- 301 people
- Sponsor
- Boston Scientific Corporation
Sinus Node Disease., First Degree Atrioventricular Block.
Minimizing Ventricular Pacing
The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality…
- Trial name
- NCT01611389
- Testing
- Prolonging atrioventricular (AV) delay., Standard atrioventricular (AV) delay.
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Military Institute od Medicine National Research Institute
Acute Respiratory Distress Syndrome
Evaluation of POC Lung Ultrasound Combined With Pressure-volume Curve to Titration Adjust PEEP for ARDS Lung Recruitment
Using lung ultrasound re-aeration score(LUS-RAS) combined with pressure-volume curve(PVC) adjust maintain positive end-expiratory pressure(PEEP) after recruitment maneuver, to achieve real-time adjustment, reduce…
- Trial name
- NCT03076450
- Testing
- Lung Ultrasound, Maximum Oxygenation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital
Arrhythmia Prophylaxis, Ventricular Arrhythmia
Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator (ICD) Interventions or Death
The Primary objective was to assess the efficacy of Celivarone for the prevention of Implantable Cardioverter Defibrillator (ICD) interventions or death.
- Trial name
- ALPHEE (NCT00993382)
- Testing
- Celivarone, Amiodarone
- Where
- 151 sites in United States, Argentina and 24 more
- Volunteers
- 486 people
- Sponsor
- Sanofi
Monomorphic Ventricular Tachycardia
Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia
To compare the efficacy and safety of substrate-based radiofrequency catheter ablation vs. antiarrhythmic drug therapy in patients with ischemic cardiomyopathy and scar-related sustained monomorphic ventricular tachycardia.
- Trial name
- NCT03734562
- Testing
- Ablation, Antiarrhythmic drug
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Tetralogy of Fallot, Implantable Defibrillator User
French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator
National french registry of patients with tetralogy of Fallot and implantable cardioverter defibrillator.
- Conditions
- Tetralogy of Fallot, Implantable Defibrillator User, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- DAI-T4F (NCT03837574)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Paris Sudden Death Expertise Center
Ventricular Tachycardia
Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator
The purpose of this pilot trial is to determine the feasibility of a large, multi-center randomized clinical trial aimed to test whether a treatment strategy of percutaneous catheter ablation of ventricular tachycardia (VT) is…
- Trial name
- CALYPSO (NCT01576042)
- Testing
- amiodarone, sotalol, Biosense Webster's NAVI-STAR Thermo-Cool
- Where
- 5 sites in United States
- Volunteers
- 27 people
- Sponsor
- Duke University