Clinical trials: Arrhythmias Cardiac
Atrial Fibrillation, Atrial Tachyarrhythmia
LEAF - Low Energy In Atrial Fibrillation
The purpose of the study is to demonstrate the efficiency on AT / AF prevention and termination of a new algorithm contained in the Medtronic AT500 Antitachycardia device in patients with conventional pacemaker indications.
- Trial name
- NCT00157781
- Testing
- Medtronic AT500
- Volunteers
- 237 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiac Arrhythmia
Patient Reported Outcome Measures for Ablation of Cardiac Arrhythmias
A multicentre, prospective observational study to develop, evaluate and validate Patient Reported Outcome Measures (PROMs) for patients treated with cardiac ablation for symptomatic cardiac arrhythmias
- Trial name
- NCT01672528
- Testing
- Interview, Questionnaires
- Where
- 3 sites in United Kingdom
- Volunteers
- 586 people
- Sponsor
- Cardiff and Vale University Health Board
Sudden Cardiac Death Due to Cardiac Arrhythmia, Cardiomyopathies
Personalized Risk Prediction of Sudden Cardiac Death
Sudden cardiac death (SCD) is the final result of cardiac arrest (CA) , defined as an abrupt and unexpected loss of cardiovascular function resulting in circulatory collapse and death.
- Conditions
- Sudden Cardiac Death Due to Cardiac Arrhythmia, Cardiomyopathies, Ischemic Heart Disease, Cardiovascular Diseases
- Trial name
- RESPECT (NCT06321900)
- Testing
- Personalized risk model
- Where
- Italy
- Volunteers
- 1,050 people
- Sponsor
- Istituto Auxologico Italiano
Subarachnoid Hemorrhage (SAH), Tachycardia
Impact of Tachycardia on Outcome After Subarachnoid Hemorrhage (SAH)
The purpose of this retrospective study is to test the hypothesis that uncontrolled tachycardia serves as a risk factor for adverse cardiovascular events and poor outcome after Subarachnoid Hemorrhage (SAH).
- Trial name
- NCT01585311
- Where
- United States
- Volunteers
- 1,540 people
- Sponsor
- Columbia University
Arrythmia, Syncope
Arrhythmia Identification in Syncope Patients: ePatch® Versus 24h Holter
This study is a Multi-center, prospective, randomized, unblinded, two-arm study to assess if 7-days of cardiac monitoring using the ePatch Holter results in identification of more clinically actionable arrythmia for patients with…
- Trial name
- NCT06310707
- Testing
- ePatch ® Extended Wear Holter (EWH)
- Where
- 2 sites in France, Germany
- Volunteers
- 55 people
- Sponsor
- Philips Clinical & Medical Affairs Global
MACE, Arrhythmia, Pericardial Effusion and Survival
Cardiac Safety Management and Immune Microenvironment Changes After Thoracic Radiotherapy: A Prospective Observational Study
The goal of this observational study is to learn about cardiac safety monitoring after thoracic radiotherapy in adults with thoracic tumors.
- Trial name
- NCT07669493
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Hebei Medical University Fourth Hospital
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Stroke, Atrial Fibrillation
The Incidence of New-brain Lesions on Brain MRI and Safety Between Edoxaban and Apixaban in Patients with Stroke and Nonvalvular Atrial Fibrillation
This study aims to determine whether there is a difference in brain lesion occurrence and safety when brain MRI is followed up between edoxaban and apixaban in stroke patients with nonvalvular atrial fibrillation through…
- Trial name
- APIXABAN (NCT06864052)
- Testing
- Administration of Apixaban, Administration of Edoxaban
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Ewha Womans University Seoul Hospital
Heart Failure, Arrhythmias, Cardiac
Monitoring of Fluid Status in Heart Failure Patients by Intrathoracic Impedance Measurement in Japan (J-HomeCARE II)
The new BIOTRONIK implantable cardioverter defibrillator (ICD) family Lumax 540 is capable of measuring the intrathoracic impedance on a daily basis and transmission of impedance trend data via the Home Monitoring technology.
- Trial name
- NCT01221649
- Testing
- ICD/CRT-D
- Where
- 4 sites in Japan
- Volunteers
- 198 people
- Sponsor
- Biotronik Japan, Inc.
Atrial Flutter, Atrial Fibrillation
Cryoballoon Pulmonary Venous Isolation in Patients Referred for Typical Atrial Flutter Ablation
Background: Atrial fibrillation is frequently associated with typical atrial flutter in clinical practice. If the radical treatment of atrial flutter by radiofrequency catheter is achieved in most cases without recurrence, it…
- Trial name
- PAF CRIOBLAF (NCT01521988)
- Testing
- Atrial flutter ablation, Atrial flutter ablation and pulmonary vein isolation
- Where
- 15 sites in France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Rouen
Ventricular Tachycardia Ablation
Repolarization and Activation Mapping in Ventricular Tachycardia Ablation: the REDEMPTION Study
The aim of this study is to prospectively evaluate a novel sinus rhythm mapping strategy for ventricular tachycardia (VT) ablation based on combined ventricular repolarization and activation (depolarization) mapping…
- Trial name
- REDEMPTION (NCT06765746)
- Testing
- Ventricular tachycardia ablation
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Atrial Fibrillation (AF)
Study to Evaluate the effIcacy and Safety of Abelacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral Anticoagulation
This OLE part is an optional, single arm, multicenter, open-label extension (OLE) added to the core part to assess the long-term safety, tolerability, the incidence of ischemic stroke or SE and bleeding events of abelacimab in…
- Trial name
- LILAC-TIMI 76 (NCT07739888)
- Testing
- Abelacimab
- Volunteers
- 2,500 people
- Sponsor
- Novartis Pharmaceuticals
Atrial Fibrillation, Prescribing Practices
Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF
The SUPPORT-AF study aims to improve rates of anticoagulation (AC) in atrial fibrillation (AF) patients by developing and delivering supportive tools and educational materials to providers treating patients with AF.
- Conditions
- Atrial Fibrillation, Prescribing Practices, Anticoagulants
- Trial name
- SUPPORT-AF (NCT03583008)
- Testing
- Anticoagulation (AC) Intervention--Academic Detailing, Anticoagulation (AC) Intervention--Prescribing Practices
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Atrial Fibrillation
Effects of Fish Oil on Post Ablation Arrhythmias
To determine if peri-operative treatment with omega-3 fatty acids is associated with a decrease in the incidence of early recurrences of atrial arrhythmias (within 30 days) and an improvement in probability of long-term…
- Trial name
- NCT00791089
- Testing
- LOVAZA Omega 3-acid ethyl esters, LOVAZA
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA)
Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation
Post-operative atrial fibrillation (POAF) is a frequent complication of surgical aortic valve replacement, affecting 38 to 63% of patients, and increasing risks of stroke, heart failure, and long-term mortality.
- Conditions
- Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA), Heart Failure, Myocardial Infarction (MI)
- Trial name
- VAGASTIMA-PILT (NCT07891390)
- Testing
- tVNS session on the left earlobe
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Ventricular Tachycardia, Cardiovascular Diseases
Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial
The ABCD clinical study (ClinicalTrials.gov Identifier NCT00187291) was designed to determine if a T-Wave Alternans (TWA) test is equivalent to an Electrophysiology Study (EPS) in predicting life-threatening heart rhythms in…
- Conditions
- Ventricular Tachycardia, Cardiovascular Diseases, Arrythmia, CVD
- Trial name
- ABCD (NCT00583297)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- CardioDx
Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS
POLish Registry of CArdioneuroablation and CArdioneuromodulation
The multicentre observational study POL-CA involves a wide spectrum of patients with a history of syncopy. The study recruits patients with diagnosed vasovagal syndrome, cardioinhibitory carotid sinus syndrome, symptomatic sinus…
- Conditions
- Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS, Symptomatic Sinus Bradycardia SB or Atrioventricular Block AV, Postural Orthostatic Tachycardia Syndrome POTS
- Trial name
- POL-CA (NCT07196397)
- Testing
- cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- SABAMED Medical Center Ltd.
Neurobehavioral Manifestations, Atrial Fibrillation
Frontal Cognitive Control Functions Before and After Percutaneous Catheter Procedures in Treatment of Atrial Fibrillation
Atrial fibrillation is a common arrythmia. It is an independent risk factor for stroke. There for anticoagulation therapy is used for atrial fibrillation patients.
- Trial name
- NCT02306460
- Where
- Finland
- Volunteers
- 17 people
- Sponsor
- Tampere University Hospital
Bradycardia
Registry of Sleep Apnea Monitoring and Atrial Fibrillation in Pacemaker Patients (RESPIRE)
The purpose of the study is to evaluate at 12 Months follow-up the association between Atrial Fibrillation (AF) and Sleep Apnea (SA) severity based on data measured and stored in REPLY 200 DR pacemaker.
- Trial name
- NCT01922726
- Where
- Spain
- Volunteers
- 1,257 people
- Sponsor
- MicroPort CRM
Atrial Fibrillation (AF)
Noninvasive Mapping Before Surgical Ablation
The purpose of this study is to assess the electrophysiological mechanism of atrial fibrillation by means of a beat-to-beat noninvasive 3D mapping method in patients with concomitant persistent and long-standing persistent atrial…
- Trial name
- NIMSA (NCT06803615)
- Testing
- Electrocardiographic imaging
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Vienna