Clinical trials: Arterial Aneurysm
Intracranial Aneurysm
Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil
The primary objective of this study is to gather post market data on the Penumbra SMART COIL® System (Smart System) in the treatment of intracranial aneurysms and other malformations.
- Trial name
- SMART (NCT02729740)
- Testing
- Penumbra Smart Coil, Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)
- Where
- 72 sites in United States, Canada
- Volunteers
- 995 people
- Sponsor
- Penumbra Inc.
Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm)
Quick Yielding Modified Short-Distance Fenestration Technique for the Treatment of Complex Aortic Arch Diseases: a Multicenter Single-Arm Objective Performance Criteria Trial(QYM-Tech Study)
Background: This study investigates the safety and efficacy of a novel surgical approach combining thoracic endovascular aortic repair (TEVAR) and in situ fenestration reconstruction of supra-aortic branches using the Quick…
- Conditions
- Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm), Thoracic Pseudoaneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT06639243
- Testing
- QYM Technique
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cerebral Aneurysm, Menopause
Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial
This study aims to determine if hormone replacement therapy, given during perimenopause may prevent the progression of saccular cerebral aneurysms.
- Conditions
- Cerebral Aneurysm, Menopause, Treatment
- Trial name
- EPPA (NCT01895881)
- Testing
- Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Intracranial Aneurysm
Diversion-p64 Post Market Clinical Follow-Up Study to Assess Safety and Effectiveness of the p64 Flow Modulation Device
The purpose of this study is to assess safety and effectiveness of the p64 Flow Modulation Device.
- Trial name
- NCT02600364
- Where
- 26 sites in Argentina, Belgium and 8 more
- Volunteers
- 450 people
- Sponsor
- Phenox GmbH
Abdominal Aortic Aneurysm, Endovascular Aortic Repair
Optimizing CO2 Injection Technique for EVAR
Automated carbon dioxide (CO2) angiography is considered a safe diagnostic alternative to standard iodinated contrast medium (ICM) for endovascular aortic repair (EVAR) of abdominal aortic aneurysm (AAA), especially in patients…
- Trial name
- NCT05304026
- Testing
- Technique 1, Technique 2, Technique 3
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Bologna
Intracranial Aneurysm
Clinical Performance Evaluation of RDX-Aneurysm for Detecting Intracranial Aneurysms on TOF-MRA
This retrospective, multi-center, observational case-control study evaluates the standalone performance of RDX-Aneurysm, a computer-assisted detection software, for detecting and marking suspected saccular intracranial aneurysm…
- Trial name
- RDX-Aneurysm (NCT07655635)
- Where
- 3 sites in Taiwan
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Popliteal Artery Aneurysm, Peripheral Arterial Disease
Prospective Case-control Study in Patients With PAA
The overall objective is to highlight different aspects of care in patients with PAA before and after treatment, and identifying factors that influence the outcome of PAA patients.
- Conditions
- Popliteal Artery Aneurysm, Peripheral Arterial Disease, Quality of Life
- Trial name
- NCT04188808
- Testing
- Bypass surgery
- Where
- 2 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Rebecka Hultgren
Intracranial Aneurysms
Clinical, Organizational, and Care Impact of the GetReady Digital Platform as a Clinical Decision Support Tool in the Follow-up of Patients With Cerebral Aneurysm
This study evaluates the clinical, organizational, and care impact of the GetReady digital platform as a clinical decision support tool for the follow-up of patients with cerebral aneurysm.
- Trial name
- SAFO (NCT07569562)
- Testing
- GetReady digital platform
- Volunteers
- 200 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Submacular Hemorrhage, Ruptured Retinal Arterial Macro Aneurysms
Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm
Evaluation of surgical outcome of vitrectomy with subretinal injection of recombinant tissue-plasminogen activator for submacular hemorrhage associated with retinal arterial macroanuerysms.
- Trial name
- NCT02120066
- Testing
- Vitrectomy for submacular hemorrhage, subretinal injection of tissue-plasminogen activator
- Where
- Japan
- Volunteers
- 22 people
- Sponsor
- Kyorin University
Acute Aortic Syndrome, Aortic Dissection
18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to predict disease progression in acute aortic syndrome.
- Conditions
- Acute Aortic Syndrome, Aortic Dissection, Penetrating Aortic Ulcer, Intramural Hematoma
- Trial name
- FAASt (NCT03647566)
- Testing
- 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography, CT Aortic Angiogram, Aortic MRI
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Intracranial Aneurysm
Intravascular Neuro OCT Imaging System for Aneurysm Treatment Evaluation
This is an investigational study for a new medical device called the nOCT (neuro optical coherence tomography) Imaging System, which is manufactured by Spryte Medical, LLC.
- Trial name
- INSYTE (NCT07214220)
- Testing
- Endovascular Intracranial aneurysm treatment, nOCT imaging
- Where
- 8 sites in United States, Argentina and 1 more
- Volunteers
- 67 people
- Sponsor
- Spryte Medical
Intracranial Aneurysm
International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)
This multicenter retrospective cohort study aims to evaluate and compare the technical performance, safety, and clinical outcomes of intracranial aneurysms treated with flow diverter stents and endosaccular flow disruptors.
- Trial name
- IRF (NCT06174727)
- Where
- 13 sites in United States, Canada
- Volunteers
- 5,000 people
- Sponsor
- Montefiore Medical Center
Cerebral Aneurysm
Framing Eighteen Coils in Cerebral Aneurysms Trial
This trial is being conducted in order to compare angiographic outcomes in patients receiving 0.014-0.0155" platinum framing and filling coils (larger diameter coils) versus those treated solely with coils less than 0.014" (with…
- Trial name
- FEAT (NCT01655784)
- Testing
- Coil Embolization with larger Diameter Coils, Coil Embolization with Standard Diameter Coils
- Where
- 24 sites in United States
- Volunteers
- 651 people
- Sponsor
- Vanderbilt University Medical Center
Self Efficacy, Medical Device Complication
Chinese Registry of Assisted Embolization for Unruptured Wide Necked Intracranial Aneurysm Using LVIS Stent
This study aims to investigating the efficacy and safety of low profile visualized intraluminal support (LVIS) stents for the treatment of unruptured intracranial saccular aneurysms.
- Trial name
- CRANIAL-1 (NCT02830373)
- Testing
- LVIS stents
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Popliteal Artery Aneurysm
Open Versus Endovascular Repair of Popliteal Artery Aneurysm Trial
Weakness in the wall of a blood vessel located behind the knee (popliteal artery) which leads to a swelling of this blood vessel (aneurysm) is one of the most common types of arterial aneurysms.
- Trial name
- OVERPAR (NCT01817660)
- Testing
- Open repair of popliteal artery, Endovascular repair of popliteal artery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston Medical Center
Juxta Renal Abdominal Aortic Aneurysm Without Rupture
Guo's Visceral Arteries Reconstruction :The First in Man Study of WeFlow-JAAA Stent Graft System
This study is the First in Man Study of WeFlow-JAAA Stent Graft System manufactured by EndoNom Medtech(Hangzhou) Co., Ltd.
- Trial name
- NCT04745546
- Testing
- WeFlow-JAAA Stent Graft System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Arteriovenous Malformations, Cerebral, Unruptured Brain Arteriovenous Malformation
Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations
A new endovascular route for the treatment of brain AVMs may be possible in some cases: Trans-Venous Embolization (TVE). The technique uses microcatheters to navigate to the draining veins of AVM, to reach and then fill the AVM…
- Conditions
- Arteriovenous Malformations, Cerebral, Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation
- Trial name
- TATAM (NCT03691870)
- Testing
- Standard Trans-Arterial Embolization (TAE), Trans-Venous Embolization (TVE)
- Where
- 9 sites in Canada, France
- Volunteers
- 77 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Intracranial Aneurysm, Muscular Atrophy
Minipterional Versus Pterional Craniotomy
This randomized prospective study was designed to compare the clinical, functional and aesthetic results of two surgical techniques for microsurgical clipping of anterior circulation aneurysms
- Trial name
- NCT01872741
- Testing
- Minipterional craniotomy, Pterional craniotomy
- Volunteers
- 58 people
- Sponsor
- University of Sao Paulo General Hospital
Aneurysm Cerebral
Derivo 2 Heal vs Derivo 2: In-Stent Stenosis After Flow Diversion
The goal of this clinical trial is to learn whether a coated flow diverter leads to fewer in-stent narrowings (in-stent stenosis) than an otherwise identical uncoated flow diverter when used to treat intracranial aneurysms in…
- Trial name
- NCT07420179
- Testing
- Coated Flow Diverter, Uncoated Flow Diverter
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Universität des Saarlandes
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion