Clinical trials: Arterial Aneurysm
Intracranial Arterial Aneurysm
The NUVASCULAR HARBOR Occlusion Device EU Study
The purpose of this study is to evaluate the safety and effectiveness of the HARBOR Occlusion Device for treating brain aneurysms.
- Trial name
- NCT07900464
- Testing
- HARBOR Occlusion Device
- Where
- 2 sites in Austria, Bulgaria
- Volunteers
- 30 people
- Sponsor
- Nuvascular Inc
Intracranial Aneurysm, Postoperative Pain
Effect of Bilateral Greater Occipital Nerve Block on Headache After Intracranial Aneurysm Coiling
Postoperative headache is a common complication following endovascular coil embolization of intracranial aneurysms and may increase analgesic requirements, impair patient comfort, and contribute to hemodynamic instability.
- Trial name
- NCT07910864
- Testing
- Ultrasound-Guided Bilateral Greater Occipital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Konya City Hospital
Atherosclerosis, Aortic Aneurysm
Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques
Lipid-rich atherosclerotic plaques, or "vulnerable plaques" are prone to rupture, causing local intravascular thrombosis, with subsequent grave clinical consequences.
- Conditions
- Atherosclerosis, Aortic Aneurysm, Peripheral Vascular Diseases
- Trial name
- NCT00449306
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Sheba Medical Center
Hemorrhagic Stroke, Aneurysm, Intracranial
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms
To determine safety and effectiveness of the p48 MW HPC and p64 MW HPC Flow Modulation Device in the treatment of wide-necked intracranial aneurysms.
- Conditions
- Hemorrhagic Stroke, Aneurysm, Intracranial, Saccular Aneurysm, Fusiform Aneurysm
- Trial name
- PIANO (NCT07143019)
- Testing
- Flow diversion
- Where
- 25 sites in United States
- Volunteers
- 214 people
- Sponsor
- phenox Inc.
Intracranial Aneurysm
A Study of Choydar Flow-Directed Mesh Stent in the Treatment of Unruptured Intracranial Aneurysms
The purpose of this study is to assess how safe choydar flow-directed mesh stent is and how well it works in the treatment of unruptured intracranial aneurysms (a condition in which a bulging blood vessel in the brain can burst…
- Trial name
- CROWN (NCT07228312)
- Where
- 8 sites in China
- Volunteers
- 200 people
- Sponsor
- Johnson & Johnson Medical (Shanghai) Ltd.
Intracranial Aneurysm, Unruptured Cerebral Aneurysm
Chinese Small Intracranial Aneurysm Study (CSIAS)
Intracranial aneurysms are common in the general population. The overall prevalence of unruptured intracranial aneurysms (UIAs) is estimated of 2.3-3.2% in the population without specific risk factors for SAH.
- Conditions
- Intracranial Aneurysm, Unruptured Cerebral Aneurysm, Treatment Side Effects
- Trial name
- NCT02948504
- Testing
- Coiling or Clipping
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Abdominal Aorta Aneurism, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression: the Prospective VASCUL-AID Study
Introduction: Peripheral arterial disease (PAD) and abdominal aortic aneurysm (AAA) are vascular conditions associated with significant morbidity and mortality, with 25% of AAA patients and 23% of PAD patients being at a high…
- Trial name
- VASCUL-AID-PRO (NCT07187700)
- Volunteers
- 1,100 people
- Sponsor
- Amsterdam UMC
Cerebral Aneurysm
Impact of Neurochecks on Sleep in Critically Ill Adults
Background: Following acute brain injury (ABI), patients are monitored in the intensive care unit (ICU) where providers rely on frequent neurological examinations ("neurochecks") to assess for neurodeterioration.
- Trial name
- NCT05864300
- Testing
- Neurocheck frequency
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Intracranial Aneurysm, Cerebrovascular Stenosis
Hybrid Operating Treatment of Coexistence of Intracranial Aneurysms and Cerebrovascular Stenosis
To evaluate the clinical benefits and risks of hybrid operating techniques in management of intracranial aneurysms with coexistence of atherosclerotic intracranial arterial stenosis.
- Conditions
- Intracranial Aneurysm, Cerebrovascular Stenosis, Atheroscleroses, Cerebral
- Trial name
- HOT-CIACS (NCT03204435)
- Testing
- Microsurgical aneurysmal operating techniques, endovascular techniques for cerebrovascular stenosis, endovascular techniques for intracranial aneurysms
- Where
- China
- Volunteers
- 196 people
- Sponsor
- liuxingju
Cerebral Aneurysm
Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms
This registry study will investigate the incidence of and outcomes associated with clopidogrel hyper-responsive patients treated at Methodist Dallas Medical Center, beginning in January 2018, who suffered cerebral aneurysms.
- Trial name
- NCT05945563
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Aortic Dissection, Spinal Cord Ischemia
SPIRIT: Study of the Patency of Spinal aRteries After the STABILISE Technique
The aim of the study is to evaluate the impact of the stent-assisted balloon-induced intimal disruption and relamination in aortic dissection repair (STABILISE) technique in the patency of intercostal and lumbar arteries…
- Trial name
- SPIRIT (NCT06373393)
- Testing
- STABILISE
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA
Aortic Infections and Inflammations, Mycotic Aneurysm
Study of the Aortic and Large Arterial Vessel Infections
Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions.
- Conditions
- Aortic Infections and Inflammations, Mycotic Aneurysm, Arterial Infections and Inflammations, Prosthetic Infection
- Trial name
- Repia (NCT05660733)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Iliac Aneurysm, Angiography
Iliac Branch Device Movement During Cardiac Cycle (IBD-dynamics)
The incidence of isolated common iliac artery (CIA) aneurysms is low, but in combination with an abdominal aortic aneurysm (AAA) they are found in approximately 20-40% of cases.
- Conditions
- Iliac Aneurysm, Angiography, AAA
- Trial name
- NCT03762525
- Testing
- ECG gated CTA
- Where
- 3 sites in Netherlands
- Volunteers
- 45 people
- Sponsor
- Rijnstate Hospital
Cerebrovascular Disorder
Aneurysms and Carotid Artery Block in Newborns
This study will determine the risk of brain aneurysm (abnormal outpouching of a brain artery) in young adults who had their carotid artery tied off as an infant as part of the extracorporeal membrane oxygenation (ECMO) procedure.
- Trial name
- NCT00646672
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Intracranial Aneurysm
Genetic Analysis of Familial Brain Aneurysms
This study will investigate cerebral (brain) aneurysms and their possible inheritance patterns in families. It will try to determine how often brain aneurysms occur in families in which more than one member has had an aneurysm…
- Trial name
- NCT00011856
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Aneurysm, Intracranial
An EFS Assessing the Electrolytic eCLIPs System for Treatment of Intracranial Aneurysms
The purpose of this study is to investigate the feasibility and initial clinical safety of eCLIPs device use for the treatment of wide-necked bifurcation aneurysms.
- Trial name
- NCT04886505
- Testing
- Electrolytic eCLIPs Bifurcation System
- Sponsor
- Evasc Medical Systems Corp.
Aneurysm Abdominal, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral…
- Trial name
- VASCULAIDRETRO (NCT06206369)
- Testing
- No intervention, retrospective study
- Where
- 6 sites in Finland, Germany and 4 more
- Volunteers
- 11,000 people
- Sponsor
- Amsterdam UMC, location VUmc
Intracranial Aneurysm
Prospective Study on Embolization of Intracranial Aneurysms With Pipeline™ Embolization Device
The purpose of this study is to assess the safety and effectiveness of the Pipeline™ device in the treatment of unruptured, wide-neck intracranial aneurysms.
- Trial name
- PREMIER (NCT02186561)
- Testing
- Pipeline™ Embolization Device/ Pipeline™Flex Embolization Device
- Where
- 23 sites in United States, Canada
- Volunteers
- 197 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysms
Canadian eCLIPs™ Safety and Feasibility Study Protocol
The purpose of this study is to evaluate the safety and feasibility of the eCLIPs™ Family of Products for the treatment of unruptured intracranial bifurcation aneurysms in conjunction with embolization coils.
- Trial name
- CESIS (NCT01957683)
- Testing
- eCLIPs™ Family of Products
- Where
- 5 sites in Canada
- Sponsor
- Evasc Medical Systems Corp.
Coronary Artery Disease, Aortic Aneurysm
Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique
This is a prospective, controlled observational trial of patients undergoing clinically indicated cardiothoracic computed tomography (CT), including pulmonary or aortic angiography and coronary CT angiography (CCTA).
- Conditions
- Coronary Artery Disease, Aortic Aneurysm, Pulmonary Embolism
- Trial name
- CTDOSE (NCT01272453)
- Where
- 9 sites in United States, Saudi Arabia
- Volunteers
- 2,640 people
- Sponsor
- Gilbert L. Raff, MD