Clinical trials: Arterial Bypass Graft Surgery
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Quality of Life
Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients
A diminution of quality of life is often reported by patients after coronary artery bypass graft (CABG) surgery. A part of this diminution could be explain by postoperative left ventricular (LV) dysfunction.
- Trial name
- ExeQOL (NCT02432976)
- Testing
- Exenatide, Insulin
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Heart Valve Disease
The Effects of Levosimendan on Haemodynamics in Patients Undergoing Elective Aortic Valve Replacement (AVR)Together With Coronary Artery Bypass Grafting (CABG) Surgery
Patients undergoing aortic valve replacement (AVR) surgery with coronary artery bypass grafting (CABG) are at risk of left ventricular dysfunction.
- Trial name
- NCT01210976
- Testing
- levosimendan
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- Tampere University Hospital
Cardiac Perfusion
Del Nido Cardioplegia Randomized Trial
The use of a modified depolarizing cardioplegia solution in adult cardiac surgery would allow for prolonged re-dosing intervals while providing equivalent myocardial protection.
- Trial name
- NCT02442050
- Testing
- del Nido solution, Blood-based cardioplegia
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Inova Health Care Services
Pain
A Study Comparing the Efficacy and Safety of Valdecoxib Plus Parecoxib Versus Valdecoxib Plus Placebo for the Treatment of Pain After Coronary Artery Bypass Surgery
The purpose of this study is to evaluate the efficacy and safety of parecoxib/valdecoxib therapy and placebo/valdecoxib therapy for the treatment of pain after coronary artery bypass surgery
- Trial name
- NCT00636064
- Testing
- Parecoxib Sodium/Valdecoxib
- Where
- 206 sites in United States, Argentina and 25 more
- Volunteers
- 1,671 people
- Sponsor
- Pfizer
Heart Disease, Coronary Artery Bypass Graft Triple Vessel
Evaluation of a Local Preconditioning Effect in Patients Undergoing Cardiac Surgery
The aim of the study is to analyze the potential of pressure controlled intermittent coronary sinus occlusion (PICSO) to prevent/reverse the ischemic burden as well as reperfusion injury.
- Trial name
- NCT01482780
- Testing
- PICSO
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Medical University of Vienna
Cardiovascular Surgical Procedures
The Effect of Eye Mask and Earplugs on Sleep Quality and Delirium in Coronary Artery Bypass Graft Patients: A Randomized Controlled Study
Coronary artery bypass grafting is the most commonly performed surgical procedure among cardiovascular diseases. Nursing care for patients undergoing cardiac surgery involves a process that includes preoperative preparation and…
- Trial name
- NCT06752980
- Testing
- Eye mask, Earplugs, Eye Mask and Earplugs
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Necmettin Erbakan University
Coronary Artery Bypass Graft Surgery (CABG), Patients' Expectations
Optimizing Expectations in Cardiac Surgery Patients
The purpose of this study is to evaluate the potential benefit of targeting patients' expectations before coronary artery bypass graft surgery through a brief psychoeducational intervention.
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Patients' Expectations, Coronary Heart Disease
- Trial name
- NCT01407055
- Testing
- Expectation Manipulation Intervention, Supportive Therapy
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- Philipps University Marburg
Coronary Artery Disease, Coronary Artery Bypass Grafting
Perioperative Intra-Aortic Balloon Pump (IABP) in Coronary Artery Bypass Grafting (CABG) Operations in Patients With Severely Depressed Left Ventricular Function
Since its first introduction in humans in 1962, Intra-Aortic Balloon Pump (IABP) is now the most commonly used therapeutic option to support failing heart in cardiac surgery.
- Trial name
- NCT00881192
- Testing
- IABP
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- IRCCS Policlinico S. Donato
Coronary Artery Disease, Blood Transfusion Complication
Re-infusion of Unwashed Shed Blood During Off-pump Surgery
To assess the efficacy and side-effects of re-infusion of unwashed shed blood during off-pump coronary artery surgery using a novel cardiotomy circuit.
- Conditions
- Coronary Artery Disease, Blood Transfusion Complication, Cardiovascular Complication
- Trial name
- NCT06358079
- Testing
- Re-infusion of unwashed shed blood
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Coronary Artery Disease, Surgical Wound Infection
Outcomes of Total Arterial Coronary Artery Bypass Grafting
"real-life" retrospective multicentric database for the analysis of the long term outcomes of total arterial CABG in comparison to saphenous vein based CABG
- Trial name
- MOZART (NCT03231527)
- Testing
- coronary artery bypass grafting (CABG)
- Where
- 4 sites in Belgium, Italy and 2 more
- Sponsor
- University of Glasgow
Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery
From Prehabilitation to Rehabilitation (Prehab2Rehab): Digitally Supported Short-Term Prehabilitation Prior to Cardiac Surgery
Prehab2Rehab is a prospective single-arm feasibility study evaluating the implementation of a multimodal, digitally supported prehabilitation program for adults awaiting elective cardiac surgery.
- Conditions
- Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery, Surgical Closure of an Atrial Septal Defect (ASD)
- Trial name
- Prehab2Rehab (NCT07716761)
- Testing
- Digitally supported prehabilitation program
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
Coronary Artery Disease
Follow-up of Coronary Artery Bypass Graft Patency by Multislice Computed Tomography
Coronary artery disease is a major cause of morbidity and mortality across the world and coronary artery bypass surgery (CABG) is the most common surgical procedure for treatment.
- Trial name
- NCT00712153
- Volunteers
- 36 people
- Sponsor
- Far Eastern Memorial Hospital
Coronary Artery Disease
Bypass Surgery Versus Everolimus-Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST)
The purpose of this study is to determine whether the safety and efficacy of coronary stent implantation using Everolimus-Eluting Coronary Stent System (Abbott, Boston Scientific) is not inferior to coronary artery bypass…
- Trial name
- BEST (NCT00997828)
- Testing
- everolimus-eluting stent, coronary artery bypass graft surgery
- Where
- 27 sites in China, Malaysia and 2 more
- Volunteers
- 888 people
- Sponsor
- Seung-Jung Park
Carotid Endarterectomy, Coronary Artery Bypass Grafting
Multidisciplinary CAE and CABG Surgery to Optimize the Management of High-risk Patients During the Perioperative Period
This project uses concurrent CEA+CABG combined surgery on high-risk patients with severe carotid artery stenosis and severe coronary artery stenosis.
- Trial name
- NCT04960488
- Testing
- carotid endarterectomy and coronary artery bypass grafting
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Acute Coronary Syndrome
Ticagrelor Removal Study Using CytoSorb® 300 mL Device During CPB in Patients Undergoing Emergent Cardiothoracic Surgery
The aim of CyTation is to demonstrate intra-operative removal of ticagrelor by CytoSorb® hemadsorption in patients on ticagrelor undergoing emergent cardiothoracic surgery requiring CPB, using platelet reactivity to adenosine…
- Trial name
- CyTation (NCT04625764)
- Testing
- Blood sampling and analysis
- Where
- 4 sites in Germany, Luxembourg
- Volunteers
- 6 people
- Sponsor
- CytoSorbents Europe GmbH
Cardiovascular Disease
Effect of Peer Support Intervention on Early Recovery Outcomes Post Coronary Artery Bypass Graft Surgery
Recovery from coronary artery bypass graft (CABG) surgery is a complex process involving physical recuperation and psychological adjustment.
- Trial name
- NCT01775228
- Testing
- Peer Support
- Where
- 3 sites in Canada
- Volunteers
- 185 people
- Sponsor
- University of Calgary