Clinical trials: Arterial Calcification
Coronary Artery Calcification, Arterial Stiffness
The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health
The purpose of this study is to examine the effect of menaquinone-7 (MK-7) supplementation on cardiovascular, metabolic, and bone health.
- Trial name
- InterVitaminK (NCT05259046)
- Testing
- Menaquinone-7 (MK-7) tablet (333 µg)
- Where
- Denmark
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Atherosclerosis
Effects of Omega-3 Fatty Acids and Menaquinone-7 on Thrombotic Tendency
Omega-3 fatty acids are notably present in fish oil and krill oil, and are known to have beneficial effects on the vasculature. Vitamin K2 is known for preventing vascular calcification.
- Trial name
- NCT00732576
- Testing
- menaquinone-7, fish oil, krill oil
- Where
- Netherlands
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Renal Dialysis, Cardiovascular Diseases
Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients
The aim of this cross-sectional study is to determine the correlation of coronary artery calcification as measured by electron-beam computerized tomography and coronary flow reserve measured by trans-thoracic Doppler…
- Conditions
- Renal Dialysis, Cardiovascular Diseases, Atherosclerosis, Inflammation
- Trial name
- NCT00921089
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Coronary Artery Calcification
The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Patients
This study aim to observe the preventive effect and the long term safety of low calcium dialysis on coronary artery calcification in Maintenance hemodialysis (MHD) patients.
- Trial name
- NCT02498457
- Testing
- low calcium dialysis
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Aortic Aneurysm
Validation of a Software and the Follow-up of Anteropoterior Migration of Stent
The treatment of aortic aneurysms is today based on different indicators (diameters, lengths, angles, volumes of the arteries) measured on CT scan images. Several indicators are time consuming and complicatated to measure.
- Trial name
- ASMOT (NCT05287828)
- Testing
- Surgeons CT scan analysis, PRAEVAorta CT scan analysis
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Nurea
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Cardiovascular Disease (CVD)
Cardiovascular Risk Assessment and Coronary Calcium Score in Thai MASLD Patients
Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in Thailand and is strongly linked to metabolic risk factors such as obesity, diabetes, hypertension, and dyslipidemia.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Cardiovascular Disease (CVD), Coronary Artery Calcification
- Trial name
- MASLD-CAC (NCT07865936)
- Where
- Thailand
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Watcharasak Chotiyaputta
Coronary Artery Disease (CAD), Coronary Artery Calcification
Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT)
SUSPECT is a prospective, single-center, cohort study of 250 military aircrew at the Center for Man in Aviation, Royal Netherlands Air Force.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Calcification, Occupational Diseases, Aviator's; Disease
- Trial name
- SUSPECT (NCT05508893)
- Testing
- CT Angiography, Exercise stress test
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Peripheral Arterial Disease, Claudication
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease
The purpose of this study is to understand the effects of fish oil supplement (containing parts of omega-3 fatty acids) on inflammation.
- Conditions
- Peripheral Arterial Disease, Claudication, Claudication, Intermittent, Vascular Occlusion
- Trial name
- NCT02719665
- Testing
- SPM Emulsion, Dose-modality, SPM Softgel, Dose-Modality
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Atherosclerosis, Cardiovascular Disease
A Prospective Study on Predictive Value of Non-Invasive Atherosclerotic Measurements in Elderly Chinese
The purpose of this study is to determine whether non-invasive atherosclerotic measurements (baPWV, IMT, FMD, CACS, ABI) are valuable predictors for cardiovascular events in elderly.
- Trial name
- NCT01208116
- Testing
- Cardiovascular events
- Where
- China
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases
Immunomodulatory Effects of PCSK9 Inhibition
Cardiovascular disease (CVD) represents the leading cause of death worldwide. While medications, such as statins, significantly reduce atherosclerotic CVD (ASCVD) risk by lowering low density lipoprotein levels, they may also…
- Conditions
- Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases, Atherosclerosis, Arterial Inflammation
- Trial name
- INSPIRAR (NCT05720156)
- Testing
- 99mTc-tilmanocept SPECT/CT scanning
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Arterial Calcification, Aortic Stiffness
Short and Long-term Results of Arterial Stiffness and Central Aortic Pressure After Kidney Transplantation
Central blood pressure and pulse wave velocity were measured using a Complior Analyse device in Short and Long-term after kidney transplantation.
- Conditions
- Arterial Calcification, Aortic Stiffness, High Blood Pressure (& [Essential Hypertension])
- Trial name
- PWV/CP/KTx (NCT02443454)
- Testing
- Device: Complior Analyse System, Tanita BC 418- Bioelectrical impedance analysis
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Atherosclerosis, Atheroscleroses, Coronary
Detection of Coronary Artery Calcifications by Whole Blood Transcriptome Analyzed by Artificial InTelligence Algorithms
The goal of this observational study is to determine the diagnostic accuracy of peripheral whole blood transcriptomes analyzed by an artificial intelligence algorithm to detect the presence and extent of coronary calcification in…
- Conditions
- Atherosclerosis, Atheroscleroses, Coronary, Atherosclerotic Plaque
- Trial name
- CAC-TRAIT (NCT05619042)
- Where
- Argentina
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Santiago Gabriel Miriuka
Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk
Breast Artery Calcification (BAC) and Female Cardiovascular Disease
The investigators are recruiting women with and without Breast Artery Calcification (BAC) on their mammograms. Each participant in the study will undergo bloodwork at a Northwell Health lab, a cardiac CT scan, and fill out some…
- Conditions
- Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk, Cardiovascular Disease Prevention
- Trial name
- NCT07809932
- Testing
- Cardiac CT Scan, Bloodwork
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Metabolic Bone Disorder
Investigations of the Effect of MK-7 on Bone and Glucose Metabolism and Arterial Calcification
The aims of the present study are to investigate the effect of vitamin K2 on bone turnover, bone mass, bone structure, glucose metabolism, and arteriosclerosis.
- Trial name
- K2vita (NCT01922804)
- Testing
- K2 vitamin
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Arterial Calcification Due to Deficiency of CD73
Diagnosis and Treatment of Patients With Inborn Errors of Metabolism
Researchers intend on diagnosing and treating certain inborn errors of metabolism. By doing this researchers hope to expand their knowledge about these disorders and provide access to patients of interest for research, teaching…
- Trial name
- NCT00369421
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Diabetes, Coronary Artery Calcification
A Study Comparing Skin Fluorescence to Coronary Artery Calcification
This study examines the relationship between the SCOUT DM device and coronary artery calcification as determined by rapid computed tomography in patients at risk for coronary heart disease.
- Trial name
- CACS (NCT00895427)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Monckeberg Medial Calcific Sclerosis
Mechanical Stress Effects on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Among Athletes
The main objective of this study is to obtain data for the integrated analysis of morphological, functional and biomechanical parameters pertaining to lower limb arteries in various categories of elite athletes (without…
- Trial name
- MediaSport (NCT01577576)
- Where
- 2 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Kidney Disease
CRICKET Study, Coronary Calcium Scores in Patients With Chronic Kidney Disease
Patients with Chronic Kidney Disease (CKD) have been shown to have high coronary calcium scores (CAC), but the temporal association between Glomerular Filtration Rate, CVD risk factors and CAC has not been described.
- Trial name
- NCT00142636
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Cardiovascular Diseases, Heart Diseases
Coronary Artery Calcification in Type 1 Diabetes
To investigate the occurrence and associated risk factors for subclinical heart disease in persons with insulin-dependent diabetes mellitus (IDDM).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus
- Trial name
- NCT00005754
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Arteriopathic Disease, Arterial Calcification
The Effects of Hemodialysis Session on Vascular Stiffness
Central blood pressure and pulse wave velocity were measured using a Complior Analyse device before and immediately after the end of the dialysis session.
- Conditions
- Arteriopathic Disease, Arterial Calcification, Complication of Hemodialysis, Aortic Stiffness
- Trial name
- PWV/CP/HD (NCT02443376)
- Testing
- Complior Analyse System, BCM- Body Composition Monitor
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw