Clinical trials: Arterial Disease
Coronary Artery Disease
Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents
Since the advent of coronary stents, in-stent restenosis has proven to be the major limitation of interventional cardiology, occurring in as many as 30% of patients.
- Trial name
- GERSHWIN (NCT00627900)
- Testing
- bare metal stent, Cypher-Stent (Implantation of a sirolimus-eluting stent)
- Where
- Germany
- Volunteers
- 958 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Coronary Artery Disease
Effect of Sarpogrelate, a Serotonin Receptor Antagonist, on Coronary Artery Disease
This is a prospective interventional study to assess the effect of sarpogrelate compared with aspirin in Korean type 2 diabetic patients with atherosclerosis.
- Trial name
- SAGE-CAD (NCT02607436)
- Testing
- Sarpogrelate, Aspirin
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Coronary Artery Disease (CAD)
A Phase I Study to Evaluate XTR003 in Healthy Chinese Volunteers
18F-FDG PET imaging is now considered the most effective method used in the clinical evaluation of viable myocardium. However, the need for fasting or glucose and insulin loading in the 18F-FDG PET protocol makes it unfavorable…
- Trial name
- NCT05136391
- Testing
- XTR003
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sinotau Pharmaceutical Group
Diabetic Foot, Peripheral Arterial Disease
Microwave Radiometry Thermometry for the Diagnosis of Critical Limb Ischemia in Diabetic Patients
Diagnosis of vascular involvement in diabetic foot disease remains challenging. Differential diagnosis between pure neuropathic or neuro-ischemic diabetic foot requires a combination of clinical examination, medical history and…
- Conditions
- Diabetic Foot, Peripheral Arterial Disease, Ischaemic Neuropathy
- Trial name
- NCT03002116
- Testing
- Tissue thermometry using non-invasive microwave radiometry device
- Where
- 3 sites in Greece, United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Attikon Hospital
Cardiovascular Diseases, Atherosclerosis
Epidemiology of Coronary Artery Calcification
Using subjects from the Rochester Family Heart Study (RFHS), to characterize predictors of coronary artery calcification (CAC), a potent marker of atherosclerosis, among individuals from the general population.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Coronary Arteriosclerosis, Heart Diseases
- Trial name
- ECAC (NCT00005349)
- Volunteers
- 1,736 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pulmonary Artery Hypertension
Evaluation of Respiratory Muscle in Patient With Pulmonary Arterial Hypertension
The aim of the study is that evaluation of basic and accessory respiratory muscles and their relationship of six minute walk test in patient with pulmonary arterial hypertension (PAH)
- Trial name
- NCT05056532
- Testing
- patient assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Giresun University
Coronary Artery Disease
F-18 Rhodamine 6G PET Imaging for Myocardial Blood Flow
Use of novel radio-pharmaceutical Rhodamine 6G to determine myocardial blood flow
- Trial name
- NCT04528758
- Testing
- Rhodamine 6G
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Atherosclerosis
The Effect of Dates on Plasma Lipids, Oxidative Stress and the Atherogenicity of Serum in Healthy Adults
It has been proven in in-vitro studies that dates decrease the oxidative stress in serum. There have been no in-vivo studies to this date.
- Trial name
- NCT00750789
- Testing
- dates
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Skin Cancer, Skin Diseases
Multi-modal Quantitative Imaging of the Skin
This clinical trial is about evaluating the suitability of multi-modal imaging technology, which covers virtually the entire body, to evaluate the possibility of screening and early detection of disease.
- Conditions
- Skin Cancer, Skin Diseases, Atopic Dermatitis, Psoriasis
- Trial name
- DermaFlow (NCT06989216)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Low Intensity Shockwave Therapy for Erectile Dysfunction
Low-intensity shockwave therapy (LiSWT) has been deemed "a safe and well-tolerated procedure but its efficacy for the treatment of ED is doubtful and deserves more investigation" by the European Society of Sexual Medicine.
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy, Erectile Dysfunction Due to General Medical Condition
- Trial name
- NCT04434352
- Testing
- Storz Duolith Low-Intensity Shockwave Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Labor Pain, Analgesia
Effect of Different Labour Analgesics on Maternal and Fetal Blood Flow Observed by Doppler Ultrasonography
Background: The purpose of this study was to see how intrathecal injections of sufentanil, ropivacaine, and sufentanil added to ropivacaine affected blood flow in the uterine artery, umbilical artery, and middle cerebral artery…
- Conditions
- Labor Pain, Analgesia, Fetus Disorder
- Trial name
- NCT06099938
- Testing
- sufentanil, ropivacaine
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Cerebral Arterial Diseases
Modulation of Brain Blood Flow Using Dichoptic Visual and Auditory Stimulation
Modulation of brain blood flow using dichoptic Visual and Auditory stimulation using REVIVIEW system will be evaluated.
- Trial name
- NCT03632564
- Testing
- REVIVIEW dichoptic audio-visual stimulation
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Visior Technologies Ltd.
Cerebral Amyloid Angiopathy, Intracranial Hemorrhages
Multimodal Biomarkers for Diagnosis and Prognosis in CAA
By combination of plasma (Aβ40, Aβ42, total tau, and phosphorylated tau, etc.), genetic (ApoE ε2 or ε4 allele), MRI (cerebral perfusion, microbleeds, cortical superficial siderosis, enlarged perivascular space, etc.) and PET…
- Conditions
- Cerebral Amyloid Angiopathy, Intracranial Hemorrhages, Alzheimer Disease
- Trial name
- CAA (NCT03969732)
- Testing
- 1. amyloid PET；2. T807 PET
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atherosclerosis, Metabolic Syndrome
Prolonged Sitting on Responses to Short-Term Exercise Training
Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.
- Trial name
- NCT03352063
- Testing
- Prolonged sitting with exercise, Active walking with exercise.
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Coronary Artery Disease, Artificial Heart Device User
Deep Learning Algorithm for Detecting Obstructive Coronary Artery Disease Using Fundus Photographs
Artificial Intelligence, trained through model learning, can quickly perform medical image recognition and is widely used in early disease screening and assisted diagnosis.
- Trial name
- NCT06102226
- Testing
- coronary artery imaging (coronary CTA or coronary angiography)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Yong Zeng
Inflammatory Bowel Disease, Crohn Disease
Vascular Dysfunction in Paediatric IBD
Inflammatory Bowel Diseases (IBD) is a group of relapsing and remitting gut inflammatory conditions acquired due to genetic susceptibility and/or environmental triggers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT02161640
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Coronary Artery Disease
Magnetic Navigation for Contrast and Radiation Reduction
Rationale: Magnetic navigation in complex lesions/vessels may result in reduced contrast and irradiation for patients undergoing percutaneous coronary intervention. The investigators aim to compare the use of the 2 techniques.
- Trial name
- MAGNA (NCT01276808)
- Testing
- Magnetic navigation PCI, Conventional PCI
- Where
- Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Peripheral Arterial Disease
Artificial Intelligence for Early Detection of Peripheral Artery Disease
The goal of this clinical trial is to test an AI-based screening tool that will help to identify patients at high risk of having undiagnosed peripheral artery disease.
- Trial name
- (AID-PAD) (NCT06505317)
- Testing
- AI-based PAD screening intervention
- Volunteers
- 7,800 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypertension, Cardiovascular Risk Factor
Central Arterial Hemodynamics and Resistance Training
Resistance exercise training is one of the popular exercise modes that has been drawn the public's attention. However, existing evidence showed high-intensity resistance exercise training-induced negative adaptation on vascular…
- Trial name
- NCT04546308
- Testing
- Resistance exercise training
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atherosclerosis, Hypercholesterolemia
The Effect of Fasudil on Vascular Function in Humans
The purpose of the study is to evaluate how the rho kinase inhibitor, fasudil, affects vascular function in patients with atherosclerosis and hyperlipidemia.
- Trial name
- NCT00120718
- Testing
- fasudil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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