Clinical trials: Arterial Embolization
Migraine Disorders
MMA Embolization for Refractory Chronic Migraine
This is a prospective, multi-center, feasibility study to investigate safety and effectiveness of TRUFILL n-BCA liquid embolic system in bilateral middle meningeal artery (MMA) embolization for the treatment of refractory chronic…
- Trial name
- MIGRAINE (NCT06735833)
- Testing
- Middle Meningeal Artery embolization
- Where
- 8 sites in United States
- Volunteers
- 31 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Liver Neoplasms, Hepatocellular Cancer
Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR)
This will be multicentre a phase II randomized controlled and open-label trial. It will compare the 6-months objective response (CR+PR) rates obtained with Drug Eluting Bead Trans-Arterial Chemo-Embolization (DEB-TACE) alone…
- Trial name
- HepSTAR (NCT02958163)
- Testing
- Trans-arterial Chemo-Embolization, Doxorubicin, Stereotactic Ablative Radiotherapy
- Where
- 5 sites in Belgium
- Volunteers
- 3 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Quality of Life, Spleen Injury
Traumatic Splenic Injury and Management (SPLENIQ Study)
OBJECTIVE: To determine the quality of life (QOL) and clinical outcome after conservative therapy, embolization (proximal versus distal) or surgery in patients with traumatic splenic injury.
- Conditions
- Quality of Life, Spleen Injury, Trauma, Splenic Artery Embolization
- Trial name
- SPLENIQ (NCT03099798)
- Testing
- Questionnaires, MRI abdomen
- Where
- 10 sites in Netherlands
- Volunteers
- 106 people
- Sponsor
- Elisabeth-TweeSteden Ziekenhuis
Aneurysm, Intracranial Aneurysm
Appraising the Embolization of Aneurysms Using Balt Optima™ Coil System (APPLY Study)
In recent years, many developments have been made to the tools and techniques used to treat IAs via endovascular intervention. Specifically, to the detachable coils themselves.
- Conditions
- Aneurysm, Intracranial Aneurysm, Ruptured Aneurysm, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- APPLY (NCT04499508)
- Testing
- Optima Coil System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vascular Neurology of Southern California Inc.
Benign Prostate Hypertrophy(BPH)
Efficacy of Prostatic Arteries Embolization Using SQUIDPERI
Prostatic Artery Embolization (PAE) is a recognized mini-invasive treatment of bothersome Lower Urinary Tract Symptoms (LUTS) related to Benign Prostatic Hyperplasia (BPH).
- Trial name
- SQUID-PAE (NCT07255508)
- Testing
- Liquid embolic agent
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatocellular Carcinoma
The LC Bead Trial; Transarterial Chemoembolization of Hepatocellular Carcinoma (HCC)With a Drug-eluting Bead
This study involves the combined use of the FDA approved device, LC Bead and the FDA approved drug, Doxorubicin for the treatment of primary hepatocellular carcinoma (HCC).
- Trial name
- NCT01259024
- Testing
- transarterial chemoembolization using a drug-eluting bead
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Benign Prostatic Hyperplasia
Comparison of Glue with Microparticles in Prostatic Artery Embolization
Prostatic artery embolisation (PAE) is an alternative treatment to surgery for benign prostatic hyperplasia (BPH). It has been practised since 2012 and numerous publications have proved not only its safety but also its efficacy.
- Trial name
- EMBOLICOL (NCT06678308)
- Testing
- Embolisation with Magic Glue®, Embolisation with Embosphere®
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Almaviva Sante
Intracranial Aneurysm
Hemodynamic Analysis for Intracranial Aneurysms Recanalization After Endovascular Treatment
This study was designed to collect a large series of patients with aneurysms treated endovascularly to analyze hemodynamic factors that affect aneurysm recanalization.
- Trial name
- HARET (NCT02812108)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Aneurysms
The ENTERPRISE Study - Study of the Enterprise Self-Expanding Stent System
To evaluate the safety and feasibility of the Cordis Neurovascular Self-Expanding Stent System to facilitate endovascular coil embolization of wide neck saccular intracranial aneurysms.
- Trial name
- NCT00288405
- Testing
- Cordis Self Expanding Stent
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Codman & Shurtleff
Knee Osteoarthritis, Pain, Musculoskeletal
Intra-articular Corticosteroid Injection in GAE for Knee Knee Osteoarthritis
The goal of this clinical trial is to investigate the effectiveness and safety of intra-articular corticosteroid injection (IACI) in alleviating post-procedural pain and improving early outcomes in patients undergoing geniculate…
- Trial name
- NCT06514716
- Testing
- Geniculate Artery Embolization with Intra-articular Corticosteroid Injection (GAE with IACI), Geniculate Artery Embolization alone (GAE alone)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Intracranial Aneurysm, Brain Aneurysm
The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices
Intracranial bifurcation aneurysms are commonly repaired with surgical and with endovascular techniques. Wide-necked bifurcation aneurysms (WNBA) are a difficult subset of aneurysms to successfully repair endovascularly, and a…
- Conditions
- Intracranial Aneurysm, Brain Aneurysm, Unruptured Cerebral Aneurysm, Ruptured Cerebral Aneurysm
- Trial name
- RISE (NCT03936647)
- Testing
- surgical clipping, simple coiling, high-porosity stenting with/ without coiling, intra-arterial flow diversion with/ without coiling, WEB embolization device
- Where
- 4 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Brain Aneurysm
Safety and Effectiveness of an Intracranial Aneurysm Embolization System for Treating Large or Giant Wide Neck Aneurysms
This clinical research study is designed to determine safety and effectiveness of the Surpass Flow Diverter (Surpass System), an investigational device developed to treat wide-neck, large or giant intracranial aneurysms.
- Trial name
- SCENT (NCT01716117)
- Testing
- Surpass Flow Diverter
- Where
- 26 sites in United States, Netherlands
- Volunteers
- 213 people
- Sponsor
- Stryker Neurovascular
Spinal Metastases
Preoperative Embolization in Surgical Treatment of Spinal Metastases.
The main purpose of this study is to assess the efficacy of preoperative embolization in decreasing operative blood loss, decreasing the need for intraoperative transfusion and facilitate surgical resection in metastatic spine…
- Trial name
- NCT01365715
- Testing
- Arteriography and preoperative embolization, Arteriography
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hepatic Cell Carcinoma
Effectiveness of Drug Eluting TACE in Primary HCC
the aim of this work to compare effectiveness of drug-eluting bead trans-arterial chemo-embolization and conventional trans-arterial chemo-embolization of hepatic cell carcinoma in the aspect of (Tumor response via m-RECIST…
- Trial name
- NCT04048317
- Testing
- HepaSphere Microspheres/Doxorubicin Hydrochloride, Lipiodol
- Volunteers
- 75 people
- Sponsor
- Assiut University
Leiomyoma
Comparison of Pain of Two Different Methods in Uterine Artery Embolization
The primary purpose of this study is to compare pain after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
- Trial name
- NCT03420248
- Testing
- Non-spherical polyvinyl alcohol particle or Tris-acryl gelatin microsphere
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Severance Hospital
Hyperplasia Prostatic, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for Benign Prostatic Obstruction
The aim of this study is to investigate the safety and efficacy of prostatic artery embolization (PAE) for patients who refuse or are not eligible for surgery with moderate-severe lower urinary tract symptoms or indwelling…
- Conditions
- Hyperplasia Prostatic, Lower Urinary Tract Symptoms, Prostatic Diseases, Urological Manifestations
- Trial name
- NCT03099421
- Testing
- Prostatic Artery Embolization
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostatic Neoplasm, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for Obstructive Uropathy Due to Prostate Cancer
The aim of this study is to investigate the safety and efficacy of prostatic artery embolization of patients with recurrent symptoms secondary to locally advanced prostatic cancer including pelvic pain, bleeding or need for…
- Conditions
- Prostatic Neoplasm, Lower Urinary Tract Symptoms, Urological Manifestations, Prostatic Diseases
- Trial name
- NCT03104907
- Testing
- Prostatic Artery Embolization
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lung Cancer
Tc99m-MAA Bronchial Artery Injection During Bronchial Embolization for Pulmonary Mass Induced Hemoptysis for Dosimetry Planning
This research study will evaluate the administration of a particle called macro-aggregated albumin (MAA) labelled with the radiotracer technetium 99m (Tc99m) as a proxy to estimate the anticipated dose of radiation to tumor and…
- Trial name
- NCT04105283
- Testing
- Tc99m-MAA
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Intracranial Aneurysm
Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS)
The Comaneci Embolization Assist Device is indicated for use in the neurovasculature as a temporary endovascular device used to assist in the coil embolization of wide-necked intracranial aneurysms with a neck width ≤ 10 mm.
- Trial name
- NCT04518670
- Testing
- Comaneci Embolization Assist Device
- Where
- 8 sites in United States
- Volunteers
- 90 people
- Sponsor
- Rapid Medical
Leiomyomas
Diffusion -and Perfusion Weighted MRI for Response Prediction of Symptomatic Leiomyomas Following Uterine Artery Embolization
It is known that volumetric response of leiomyomas following uterine artery embolization correlates well with patients clinical outcome.
- Trial name
- NCT01514617
- Testing
- Diffusion -and perfusion weighted MRI including iv contrast agent injection
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven