Clinical trials: Arterial Embolization
Liver Cancer
Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Treating Patients With Localized Liver Cancer That Cannot Be Removed by Surgery
RATIONALE: Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00949182
- Testing
- sorafenib tosylate, HACE : Doxorubicin Hydrochloride and Mitomycin C, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Superselective Adrenal Arterial Embolization for Bilateral Idiopathic Hyperaldosteronism: A Prospective Cohort Study
The most common two subtypes of primary aldosteronism (PA ) are aldosterone producing adenoma (APA) and bilateral idiopathic hyperaldosteronism (IHA).
- Trial name
- SAAE-BIH (NCT05186675)
- Testing
- superselective adrenal arterial embolization
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Uterine Fibroids
Uterine Artery Embolization(UAE) Versus High-Intensity-Focused-Ultrasound(HIFU) for Treatment of Uterine Fibroids
This study aimed to evaluate the clinical effectiveness and adverse effects of Uterine Artery Embolization (UAE), High-Intensity-Focused-Ultrasound (HIFU) in treating patients with uterine fibroid.
- Trial name
- NCT01834703
- Testing
- UAE, HIFU
- Where
- 2 sites in Hong Kong
- Volunteers
- 85 people
- Sponsor
- Chinese University of Hong Kong
Chronic SDH and the Efficacy of Embolization
Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
This study is designed to evaluate the effectiveness of endovascular embolization of middle meningeal artery following evacuation of subdural hematomas (SDHs) to assess rate of recurrence.
- Trial name
- endovascular (NCT04272996)
- Testing
- Craniotomy only, Craniotomy + Endovascular embolization of the middle meningeal vessels
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Hepatocellular Carcinoma
Hypoxic Changes in Hepatocellular Carcinoma (HCC) Following Trans Arterial Chemo Embolization and Stereotactic Radiation: Fluorine18 (18F) Fluoromisonidazole (FMISO) Imaging
[18F] FMISO Positron Emission Tomography (PET) to determine hypoxia in patients with HCC treated with TACE.
- Trial name
- NCT03303469
- Testing
- FMISO
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Alabama at Birmingham
Adenomyosis
Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis
Single blinded randomized controlled study of symptom improvement after uterine artery embolization (UAE) versus ultrasound guided percutaneous/transvaginal microwave ablation, evaluated by validated questionnaires.
- Trial name
- ADENOMIC (NCT04209127)
- Testing
- Microwave treatment via needle antenna, Embolization of uterine artery or branches thereof (routine treatment where polyvinyl alcohol particles are released into the predefined bloodstream)
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska Institutet
Haemostasis Embolisation
Use of N-Butyl Cyanoacrylate in Transarterial Emergency Embolization
NBCA is a synthetic biodegradable cyanoacrylate basis glue, modified by the addition of a monomer with adhesive, hemostatic, and antiseptic properties.
- Trial name
- NCT06301919
- Testing
- Clinical data, Imaging data, Biological data
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Thyroid Nodules
Thyroid Artery Embolization for the Treatment of Compressive Goiters.
Very few studies have investigated TAE as a treatment for goiter with compressive symptoms. What is the efficacy and safety of TAE for the treatment of compressive goiters in a population ineligible for or refusing standard…
- Trial name
- TAE (NCT07360587)
- Testing
- Thyroid Artery Embolization
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Université de Sherbrooke
Stroke, Carotid Stenosis
Effects of Carotid Stent Design on Cerebral Embolization
The goal of the proposed study is to contrast the relative efficacy of closed-cell stents versus open-cell stents in preventing periprocedural cerebral embolization in high-risk patients with symptomatic and asymptomatic…
- Trial name
- NCT00830232
- Testing
- closed-cell stent (Xact stent), Open-cell stent (Acculink carotid)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dallas VA Medical Center
Uterine Fibroids, Uterine Artery Embolization
Preemptive Analgesia Following Uterine Artery Embolization
Uterine leiomyomata, also known as fibroids, are an extremely common benign lesion being present in 30-50% of all women. Traditional surgical treatment of symptomatic fibroids has been hysterectomy in post child bearing woman.
- Trial name
- NCT01555073
- Testing
- pregabalin/celecoxib
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Northwestern University
Neuroendocrine Tumors
Systemic Therapy With or Without Upfront Transarterial Embolization for Inoperable Liver Metastasis of Neuroendocrine Tumors
The purpose of this study is to verify if adding a locoregional treatment of liver metastasis (with trans-arterial embolization-TAE) to medical treatments of proven efficacy can prolong the progression free survival of patients…
- Trial name
- LOTUS (NCT01755182)
- Testing
- approved pharmacologic therapy, TAE
- Where
- 12 sites in Italy
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute, Naples
Colorectal Cancer with Hepatic Metastases
TATE and KN046 in MCRC
A single-arm, multicenter, Phase IIA study of Intra-arterial Administration of Tirapazamine followed by Transarterial Embolization (TATE) and KN046 (recombinant humanized anti-PD-L1/CTLA-4 bispecific single-domain antibody Fc…
- Trial name
- NCT06834399
- Testing
- KN046 （PD-L1/CTLA4 BsAb）, TATE：Intra-arterial Administration of Tirapazamine followed by Transarterial Embolization
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Zhejiang Raygene Pharmaceuticals Co., Ltd
Intracranial Aneurysm
Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment
We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component.
- Trial name
- WEB-RWS (NCT07620626)
- Testing
- Intrasaccular Flow Disruption Device
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Brain Tumor, Stroke, Acute
Safety and Feasibility of the Infinity Catheter for Radial Access
The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial…
- Conditions
- Brain Tumor, Stroke, Acute, Brain Aneurysm, Intracranial Arteriovenous Malformations
- Trial name
- NCT04553549
- Testing
- Transradial approach
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Colorectal Cancer Liver Metastasis
Safety and Efficacy of Polyvinyl Alcohol Sodium Acrylate Embolization Microspheres for CRLM
This study is a prospective, multicenter, randomized controlled clinical trial to evaluate the safety and efficacy of polyvinyl alcohol sodium acrylate embolization microspheres and HepaSphere Microspheres loaded with irinotecan…
- Trial name
- NCT06021015
- Testing
- Irinotecan and polyvinyl alcohol sodium acrylate embolization microspheres（Unipearls®）, Irinotecan and HepaSphere Microspheres
- Volunteers
- 72 people
- Sponsor
- Zhongda Hospital
Benign Prostate Hyperplasia
Prostate Artery Embolization for Symptomatic Benign Prostatic Hyperplasia
The objective is to evaluate the clinical effectiveness and safety of PAE in treating patients with BPH.
- Trial name
- NCT02822924
- Testing
- Prostate artery embolization (PAE)
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Weight Loss
Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation
Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor and has a grave prognosis. Obesity is an epidemic in the US.Patients with HCC and obesity are not candidates for liver transplantation, depriving…
- Conditions
- Obesity, Weight Loss, Body Weight, Hepatocellular Carcinoma
- Trial name
- NCT02935478
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- St. Louis University
Hepatic Cell Carcinoma
Effectiveness of Drug Eluting TACE in Primary HCC
the aim of this work to compare effectiveness of drug-eluting bead trans-arterial chemo-embolization and conventional trans-arterial chemo-embolization of hepatic cell carcinoma in the aspect of (Tumor response via m-RECIST…
- Trial name
- NCT04048317
- Testing
- HepaSphere Microspheres/Doxorubicin Hydrochloride, Lipiodol
- Volunteers
- 75 people
- Sponsor
- Assiut University
Osteoarthritis (OA) of the Knee
Genicular Artery Embolization (GAE) vs inTra-articular Corticosteroid Injection for Osteoarthritic Knee Pain.
This study investigates genicular artery embolization (GAE) as a minimally invasive alternative to ntra-articular corticosteroid injections (IA) or treating knee osteoarthritis (OA) pain.
- Trial name
- GET-IN (NCT06929585)
- Testing
- Genicular artery embolization, Intra-articular injection with corticosteroids.
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- National Taiwan University Hospital
Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH)
Barrow Ruptured Aneurysm Trial
With evolving endovascular technologies there is a growing debate centered on the relative safety and efficacy of the currently accepted alternatives for the treatment of ruptured cerebral aneurysms in the face of acute…
- Trial name
- BRAT (NCT01593267)
- Testing
- coil embolization, clip occlusion
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix