Clinical trials: Arterial Hypotension
Cardiac Complications, Signs and Symptoms
Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
This is a study designed to test the hypothesis that treatment with L-carnitine will improve the quality of life and some specific symptoms and signs in patients with renal failure submitted to hemodialysis.
- Conditions
- Cardiac Complications, Signs and Symptoms, Muscle Weakness, Anemia
- Trial name
- NCT00173706
- Testing
- L-Carnitine Injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Percutaneous Nephrolithotomy
Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the surgical standard for treating large or complex renal stones. The stones are removed by passing a small telescope through the side of the patient directly into the kidney, so the stone…
- Trial name
- NCT04891484
- Testing
- Ondansetron group, Saline group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Hypotension on Induction, Frailty
EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac Surgery
Post-induction hypotension (PIH) is a common and clinically significant hemodynamic complication following general anesthesia induction.
- Conditions
- Hypotension on Induction, Frailty, Anesthesia, General
- Trial name
- PIXEL (NCT07642765)
- Testing
- EASIX Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Hypotension, Spinal Anesthesia Induced Hypotension
Perfusion Index and Spinal Hypotension in Day-Case Knee Arthroscopy
This prospective observational study aims to investigate the role of the baseline perfusion index (PI) in predicting spinal anesthesia-induced hypotension (SAIH) in ASA I-II patients undergoing day-case knee arthroscopy.
- Conditions
- Hypotension, Spinal Anesthesia Induced Hypotension, Anesthesia, Spinal, Arthroscopy
- Trial name
- NCT07747441
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara Etlik City Hospital
Adverse Effect
The Potency of Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the potency between prophylactic norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in patients with severe preeclampsia during caesarean section.
- Trial name
- NCT05035472
- Testing
- Phenylephrine, Norepinephrine
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Norepinephrine, Glypressin, Tourniquet Deflation, Hypotension
Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty
Pneumatic tourniquet is usually used in orthopedic surgeries, as it helps to decrease operative bed bleeding, and thus, maintaining a clean and dry surgical field allowing easy and clear identification of the anatomical…
- Trial name
- NCT05774067
- Testing
- Saline, Norepinephrine, glypressin
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Bladder Cancer
Hypotension Prediction Effect on AKI
It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after radical cystectomy.
- Trial name
- NCT04994639
- Testing
- BP management with HPI guidance
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Glucose Response, Blood Pressure
Effects of Meal and Exercise Sequence on Glucose and Blood Pressure Responses
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Trial name
- NCT06949683
- Testing
- Meal-Exercise, Exercise-Meal
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Intradialytic Hypotension, Intensive Care Unit ICU
Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients
This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent…
- Conditions
- Intradialytic Hypotension, Intensive Care Unit ICU, Hemodialysis Patients
- Trial name
- HyPIR-ICU (NCT07179705)
- Testing
- Hypotensive prediction index, Standard of care monitoring
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Chulalongkorn University
Septic Shock
Discontinuation Order of Vasopressors in Septic Shock
The purpose of this study is to evaluate the incidence of hypotension based on the discontinuation order of norepinephrine and vasopressin in patients receiving concomitant norepinephrine and vasopressin infusions for the…
- Trial name
- DOVSS (NCT01493102)
- Testing
- Vasopressin, Norepinephrine
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Samsung Medical Center
Post Induction Hypotension, Elderly
Ciprofol Titrated Induction in Reducing Post-induction Hypotension in Geriatric Patients
Geriatric patients undergoing general anesthesia face a significant challenge, with the induction phase contributing to 50% of hypotensive events.
- Trial name
- CTIH (NCT06258967)
- Testing
- ciprofol, propofol
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
18-45 Range of Age, Cesarean Section
Is Elective Caesarean Sections for Predicting Post-spinal Hypotension Role of Overactive Bladder?
It is to predict postspinal hypotension that may develop in patients diagnosed with overactive bladder who will undergo elective cesarean section under spinal-epidural anesthesia.
- Conditions
- 18-45 Range of Age, Cesarean Section, Primigravid
- Trial name
- NCT05624671
- Testing
- bupivacaine,fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Hypotension and Shock, Hypertension
Accuracy of Non-Invasive Blood Pressure Measurements at the Arm, Calf , and Finger
The present study was designed to assess, in a population of patients admitted to the intensive care unit and already carrying an indwelling arterial catheter, the ability of combined continuous (ClearSight™) and intermittent…
- Conditions
- Hypotension and Shock, Hypertension, Intensive Care Unit
- Trial name
- PANIC (NCT04269382)
- Testing
- Combined non-invasive intermittent (oscillometric arm cuff), non-invasive continuous (finger cuff and ClearSight device), and invasive continuous (intra-arterial catheter) BP measurements
- Where
- 3 sites in France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hypotension, Shock
Trendelenburg as a First-line Intervention in Critically Ill, Sedated, Invasively Mechanically Ventilated, Hypotensive Patients
A pilot randomized controlled trial to evaluate the efficacy and safety of Trendelenburg position in critically ill patients with hypotension, mainly patients with septic shock and post operative vasoplegia.
- Trial name
- Trend (NCT05209737)
- Testing
- Trendelenburg position, Semirecumbent position
- Where
- 2 sites in Russia
- Volunteers
- 10 people
- Sponsor
- Negovsky Reanimatology Research Institute
Elderly Patients Undergoing Elective Non-cardiac Surgery
Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference…
- Trial name
- NCT06530901
- Testing
- Multidimensional ultrasound of the inferior vena cava
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhuan Zhang
Septic Shock
Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis
Multicenter, prospective, phase 3 randomized non-blinded interventional trial of fluid treatment strategies in the first 24 hours for patients with sepsis-induced hypotension.
- Trial name
- CLOVERS (NCT03434028)
- Testing
- Early Vasopressors, Early Fluids
- Where
- 50 sites in United States
- Volunteers
- 1,563 people
- Sponsor
- Massachusetts General Hospital
Spontaneous Intracranial Hypotension
CVFs in SIH: EID vs. PCD CTM
The purpose of this research study is to compare two types of Computed Tomography Myelography (CTM) scans, one on the photon counting detector scanner (called PCD-CTM) and the other on the energy integrating detector scanner…
- Trial name
- NCT07582744
- Testing
- photon counting detector CT myelography (PCD- CTM), energy integrating detector CT myelography (EID-CTM)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Hypotension on Induction
Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Primary research hypothesis: Patients who continue their chronic ACEI therapy up to and including the morning of a non-cardiac, non-vascular surgery will experience more intraoperative hypotension than those who transiently hold…
- Trial name
- NCT01669434
- Testing
- ACEI continuation, ACEI omission
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- University of Nebraska
Cesarean Section
Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension
Background: Poor spinal anaesthesia block is common and is difficult to manage; so a technique to minimize its incidence is advisable. Hypotension is the commonest problem with spinal anesthesia.
- Trial name
- NCT02577432
- Testing
- fentanyl, Hyperbaric bupivacaine
- Volunteers
- 124 people
- Sponsor
- Dr. Soliman Fakeeh Hospital
Hypotension
Duration Threstholds of Intraoperative Hypotension
Intraoperative hypotension is common in non cardiac surgery. longer duration of intraoperative hypotension is related with postoperative morbidity and mortality.
- Trial name
- NCT03938480
- Where
- China
- Volunteers
- 37,000 people
- Sponsor
- Peking University First Hospital
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