Clinical trials: Arterial Hypotension
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Colloid Preload Versus Colloid Coload During Cesarean Deliveries
The investigators aimed to compare the methods colloid preloading and colloid coloading in terms of the incidence of maternal hypotension and impacts on neonatal outcomes.
- Trial name
- NCT02393196
- Testing
- hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®), hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sifa University
Hypertension, Fentanyl
Lidocaine Versus Fentanyl for Hemodynamic Stability
Hypertension is an important health challenge that affects millions of people across the world today and is a major risk factor for multiple system comorbidities. Intraoperative hypotension may lead to negative outcomes.
- Conditions
- Hypertension, Fentanyl, Lidocaine
- Trial name
- NCT06557473
- Testing
- Lidocaine IV, Fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Syncope, Syncope, Vasovagal
Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)
SynABPM 2 proof-of-efficacy is a retrospective, multicentre, observational study performed in patients affected by hypotensive reflex syncope who had performed two ABPMs, one before and another after any therapeutical…
- Conditions
- Syncope, Syncope, Vasovagal, Ambulatory Blood Pressure Monitoring, Antihypertensive Drugs
- Trial name
- SynABPM (NCT05729724)
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Istituto Auxologico Italiano
Complication
Data Registry of Intensive Care Unit (ICU) Siamitra and Intensive Care Unit (ICU) Salad-Samung
As a general surgical intensive care units of the biggest tertiary referral university of Thailand with more than 1,000 admissions/year, recently, more complicated perioperative care surgical patients were accepted with high…
- Trial name
- NCT01361477
- Where
- 2 sites in Thailand
- Volunteers
- 2,000 people
- Sponsor
- Mahidol University
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Hemodynamic Instability, Anesthesia
Arterial Elastance: A Predictor of Hypotension Due to Anesthesia Induction
Hypotension is very common during and after anesthesia induction. A prolonged fasting period, a patient's underlying comorbidities, a sympathetic blockade by anesthetic agents, vasodilation, a reduction in preload, and cardiac…
- Trial name
- NCT05648643
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Post-induction Hypotension (PIH), Gynecologic Oncology Patient
Carotid Doppler Parameters and Post-Induction Hypotension
Post-induction hypotension is a common complication following the induction of general anesthesia and is associated with adverse postoperative outcomes.
- Conditions
- Post-induction Hypotension (PIH), Gynecologic Oncology Patient, Ultrasonography, Doppler
- Trial name
- CDUS-PIH (NCT07385274)
- Testing
- pre- induction carotid doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Ankara City Hospital Bilkent
Orthostatic Hypotension
The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients
The goal of this clinical trial is to explore raise-bed training Orthostatic Hypotension in Parkinson's Patients. The main question it aims to answer is: Can raise-bed training improve Orthostatic Hypotension in Parkinson's…
- Trial name
- NCT06255717
- Testing
- Comprehensive rehabilitation training, Rise-bed Training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Cirrhosis, End Stage Liver Disease
Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis
Ascites is a frequent complication of patients with portal hypertension. As portal hypertension progresses, a percentage of these patients develop refractory ascites.
- Conditions
- Cirrhosis, End Stage Liver Disease, Ascites, Hypotension
- Trial name
- NCT01331785
- Testing
- Midodrine
- Where
- United States
- Sponsor
- The Cleveland Clinic
Cerebral Autoregulation
Cerebral Hemodynamics During Sustained Intra-operative Hypotension
Objective: The objective of this study is to describe the physiology of the cerebral autoregulation over time during extreme low blood pressures (BP). Study design: This is a retrospective data collection study.
- Trial name
- NCT05016648
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hypotension
Transcutaneous Electrical Acupoint Stimulation (TEAS) on Prevention Hypotension in Elderly
Despite prophylactic measures, hypotension remains a common side-effect of spinal anesthesia. Electroacupuncture influences hemodynamics.
- Trial name
- NCT05272033
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Shivering Caused by Spinal Anesthesia
Effect of Continuous Phenylephrine Infusion on Preventing Shivering After Spinal Anesthesia in Cesarean Section
This study aims to evaluate the effectiveness of continuous phenylephrine infusion at 50 mcg/min in preventing shivering after spinal anesthesia in cesarean section.
- Trial name
- NCT07663149
- Testing
- Phenylephrine
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Spinal Induced-hypotension
Comparison of Phenylephrine and Norepinephrine for Spinal-induced Hypotension
Hypotension after spinal anaesthesia for cesarean deliveries is frequently encountered. Phenylephrine an α-agonist is commonly used for the prevention and treatment of spinal-induced hypotension.
- Trial name
- NCT04789005
- Testing
- Norepinephrine, Phenylephrine
- Where
- Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Hypotension, Poor Peripheral Perfusion
Effect of Vasopressin on Tissue Oxygen Saturation in Cardiac Surgery Patients During Cardiopulmonary Bypass
The objective of this research is to compare the effect of a low dose Vasopressin infusion or placebo during cardiopulmonary bypass on vasopressor requirements, hemodynamics and tissue oxygen saturation and its recovery using…
- Trial name
- NCT01532505
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mohamed Ismail
Hypotension During Surgery
Comparison Bewteen Intraoperative HPI vs. High Mean Arterial Pressure Threshold
Intraoperative hypotension (IOH) is a common and serious complication during surgery, closely associated with poor postoperative outcomes.
- Trial name
- NCT06631482
- Testing
- Maintain HPI < 85, Maintain MAP>=73
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Hypotension, Head and Neck Cancer
The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.
The aim of the current study is to evaluate the effects of the Hypotension Prediction Index (HPI) on the degree of intraoperative hypotension in patients undergoing free flap surgery.
- Conditions
- Hypotension, Head and Neck Cancer, Perioperative Complication, Postoperative Complications
- Trial name
- NCT05738603
- Testing
- Hypotension Prediction Index
- Where
- Poland
- Volunteers
- 206 people
- Sponsor
- Jakub Szrama
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Hypotension, Anesthesia, Local
The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
This prospective observational study aimed to investigate whether there is a relationship between weight, height, BMI, abdominal circumference (AC), hip circumference (HC), and AC-to-hip ratio with the incidence of hypotension in…
- Conditions
- Hypotension, Anesthesia, Local, Cesarean Section Complications
- Trial name
- NCT05382624
- Testing
- Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Peri-dialytic Cardiac Rhythms, Intradialytic Hypotension
Trial of Variable Dialysate Bicarbonate
QTc prolongation and premature ventricular contractions (PVCs) are common in hemodialysis (HD) patients and are associated with sudden cardiac death.
- Conditions
- Peri-dialytic Cardiac Rhythms, Intradialytic Hypotension, Electrolyte Changes, pH Changes
- Trial name
- NCT05814146
- Testing
- Dialysate bicarbonate concentration, Dialysate bicarbonate concentration - telemetry monitoring
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Brigham and Women's Hospital
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