Clinical trials: Arterial Line
Post-cardiac Surgery, Intensive Care Unit Patients
Evaluation and Calibration of a Novel Non-invasive Wearable Device for Monitoring Vital Signs
The purpose of this clinical study is to compare the measurement of vital signs (blood pressure, heart rate, respiration rate, blood oxygen levels and body temperature) measured by the non-invasive, continuous and wireless BiPS…
- Trial name
- NCT04081987
- Testing
- non-invasive monitoring
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- BiPS Medical
Pulmonary Arterial Hypertension
Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)
The purpose of the study is to document the effect of first line dual oral combination therapy with macitentan 10mg and tadalafil 40mg on pulmonary vascular resistance (PVR) in treatment-naïve patients with newly diagnosed…
- Trial name
- OPTIMA (NCT02968901)
- Testing
- macitentan, tadalafil
- Where
- 18 sites in France
- Volunteers
- 46 people
- Sponsor
- Actelion
General Anesthesia, Blood Pressure
Assessment of Effectiveness of Continuous Non-invasive Haemodynamic Monitor by Compared to Invasive Blood Pressure and Pulse Oximeter Monitoring on Patients Undergoing General Anesthesia Surgeries for More Than 60 Minutes
The goal of this observational study is to assess whether the continuous non-invasive haemodynamic monitor MOH200 (measuring blood pressure as well as pulse rate) is effective or not in people undergoing general anesthetic…
- Conditions
- General Anesthesia, Blood Pressure, Pulse Rate, Arterial Line
- Trial name
- NCT06383000
- Volunteers
- 55 people
- Sponsor
- BLZ Technology (Wuhan) Co.,Ltd
Blood Pressure Measurement
Data Collection of Arterial Line Waveform and BP Values
Collect continuous systolic and diastolic blood pressure values and waveforms as recorded by an arterial line catheter and by non-invasive blood pressure (NIBP) and to collect Photoplethysmogram Pulse Oximetry (PPG) waveform in…
- Trial name
- NCT04510753
- Testing
- Arterial catheterization kit, GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor, NIBP Cuff (GE Healthcare)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sensifree Ltd.
Coronary Artery Disease, Coronary Artery Stenosis
Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth
This is a multi-center, prospective, non-randomized study. Approximately 90 patients from up to 16 centers will be entered in the study. Patients will be followed clinically for up to 5 years post-procedure.
- Trial name
- NCT00349895
- Testing
- Coronary stent implantation
- Where
- 15 sites in Austria, Belgium and 4 more
- Volunteers
- 100 people
- Sponsor
- OrbusNeich
Blood Pressure Measurement
Continuous Non-Invasive Blood Pressure System Data Collection in Comparison to Invasive Radial Arterial Pressure
The purpose of this study is to evaluate methods to modify blood pressure in humans and measure the effectiveness of such methods.
- Trial name
- NCT04456179
- Testing
- GE Datex-Ohmeda Oxy-F Finger Clip Pulse Oximeter Sensor, Arrow® arterial catheterization kit (Teleflex)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sensifree Ltd.
Hypertension, Pulmonary
A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)
The purpose of this study is to compare the two treatment strategies; first-line combination therapy (ambrisentan and tadalafil) versus first-line monotherapy (ambrisentan or tadalafil) in subjects with Pulmonary Arterial…
- Trial name
- AMBITION (NCT01178073)
- Testing
- ambrisentan, tadalafil
- Where
- 143 sites in United States, Australia and 12 more
- Volunteers
- 610 people
- Sponsor
- GlaxoSmithKline
Blood Pressure Measurement
Continuous Blood Pressure and Waveform Measurements Comparison Between Invasive Arterial Line and PPG Sensor
The purpose of this study is to compare blood pressure values (systolic, diastolic, mean arterial pressure) and waveform as recorded by a radial arterial line catheter to the waveform and values as calculated by the Sensifree's…
- Trial name
- NCT04132453
- Testing
- Arterial catheterization kit, GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor, NIBP Cuff (GE Healthcare)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sensifree Ltd.
Blood Pressure
Non-invasive Continuous Blood Pressure Monitoring
The Boppli device was designed to provide continuous non-invasive blood pressure (cNIBP) monitoring for infants, including neonates, in intensive care settings by detecting systolic, diastolic, and mean arterial blood pressure…
- Trial name
- NCT05224011
- Testing
- Boppli Infant Blood Pressure Monitor
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- PyrAmes Inc.
Healthy, Hypoxia
Controlled Acute Hypoxia Study - Abbreviated Sensor Line
The primary objective of the study is to validate the proposed claims for the OxiCable device, for pulse rate and saturation accuracy in a diverse subject population over a specified saturation range.
- Trial name
- NCT02216344
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Coronary Artery Disease, Bifurcation Lesion
Using 3D Imaging to Optimize Bifurcation Stenting
The primary purpose of this study is to determine whether bifurcation stenting guided by on-line three-dimensional optical frequency domain imaging (3D-OFDI) is superior to that with angiographic guidance by measuring incomplete…
- Trial name
- NCT02972489
- Testing
- 3D OFDI guidance arm, Angio guidance arm
- Where
- 2 sites in Japan, Netherlands
- Volunteers
- 106 people
- Sponsor
- Increase Co., Ltd.
Arterial and Midline Catheterization
Computer Assisted Instrument Guidance (CAIG) For Arterial Line Placement
The objective of this research is to verify the procedural improvements enabled by use of a CAIG system to supplement existing ultrasound guided, needle-based procedures.
- Trial name
- NCT02584673
- Testing
- Computer Assisted Instrument Guidance (CAIG), which supplements existing ultrasound capabilities.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Clear Guide Medical
SARS-CoV-2 ICU Bound
Arterial Line Patency in ICU Bound COVID-19 Patients
The health care system was completely overwhelmed by the SARS-Cov-2 virus, and ICU admissions soared as a result of the ICU doctors' increased workload.
- Trial name
- NCT04992221
- Testing
- arterial line
- Where
- Qatar
- Volunteers
- 245 people
- Sponsor
- Hamad Medical Corporation
Advanced Hepatocellular Carcinoma (HCC)
Safety and Efficacy of Paclitaxel Liposome Arterial Infusion Combined With Systemic Therapy for Second-Line Treatment of Advanced Liver Cancer
This trial is an open-label, dose-escalation, and randomized controlled Phase Ib/II clinical study for second-line treatment in participants with advanced hepatocellular carcinoma (HCC).
- Trial name
- NCT07282509
- Testing
- HA131, Enlonstobart Injection, Pembrolizumab Injection
- Volunteers
- 116 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Local Pressure Effects
Analysis of the Arterial Pressure Wave Form Through the Proxima Device
The purpose of the trial is to confirm that the presence of the Proxima 3 disposable in the arterial line doesn't significantly attenuate the arterial pressure wave form.
- Trial name
- NCT01672073
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sphere Medical Ltd.
Aortic Aneurysm, Aortic Aneurysm Abdominal
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral
- Trial name
- CLOSURE (NCT06918496)
- Testing
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
- Where
- 2 sites in Belgium, Poland
- Volunteers
- 60 people
- Sponsor
- Grena Biomed Limited
Blood Pressure, Heart Diseases
Comparison of the Non-invasive Biobeat Device With an Invasive Arterial Line
In this clinical study the investigators will compare blood pressure measurements obtained using the non-invasive, continuous and wireless Biobeat monitoring device (a wrist watch or a patch configuration) to an invasive arterial…
- Trial name
- NCT03603860
- Testing
- Non-invasive monitoring
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Biobeat Technologies Ltd.
Blood Pressure Measurement
Evaluation of Sensifree's Alpha Sensor Signal Morphology Compared to Arterial Line and PPG Signal Morphologies
The purpose of the protocol is to compare Sensifree Alpha sensor signal morphology, measured at the radial artery, to an invasive arterial line pressure signal and the oxygen saturation as read by a pulse oximeter.
- Trial name
- NCT04100668
- Testing
- Sensifree's Alpha sensor, Arrow® arterial catheterization kit (Teleflex), GE Datex-Ohmeda Oxy-F Finger Clip Pulse Oximeter Sensor
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Sensifree Ltd.
Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms
A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver
The main purpose of this study is to compare the clinical benefit, as measured by Progression-Free Survival (PFS) and Overall Survival(OS), achieved by HX008 Plus Transcatheter Arterial Chemoembolization (TACE) or Temozolomide…
- Trial name
- NCT05647954
- Testing
- HX008 + TACE, Temozolomide + TACE, Pembrolizumab
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Taizhou Hanzhong biomedical co. LTD
Blood Pressure, Heart Diseases
Comparison of Non-Invasive Blood Pressure (NIBP) Using the Biobeat Device with an Invasive Arterial Line Catheter
In this clinical study the investigators will compare blood pressure measurements obtained using the non-invasive, wireless Biobeat monitoring device (both a wrist watch and a patch configuration) to an invasive arterial line…
- Trial name
- NCT04071015
- Testing
- Non-invasive monitoring
- Where
- Israel
- Volunteers
- 250 people
- Sponsor
- Biobeat Technologies Ltd.