Clinical trials: Arterial Stiffness, Blood Pressure
Healthy
Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
This study examines the effects of carbohydrate type (high- or low-Glycemic Index (GI)) and amount (high- or low-Glycemic Load (GL)) have on blood glucose levels, blood pressure and arterial stiffness in healthy individuals.
- Trial name
- HILO (NCT01883700)
- Testing
- Boiled Pasta, Boiled Chickpeas with Oil, Instant Mashed Potatoes
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy
Lifestyles and Endothelial Dysfunction
Objectives: To analyze the relationship of physical activity, fitness, energy intake and dietary pattern with the circadian pattern of blood pressure, central and peripheral blood pressure pulse wave velocity and biological…
- Trial name
- EVIDENT (NCT01083082)
- Where
- Spain
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Training Study
Effects of High Functional Resistance Training Program on Arterial Stiffness
Study examined the effects of CrossFit training on blood vessels. The results indicate long term CrossFit training does not harm blood vessel function.
- Trial name
- NCT06935318
- Testing
- Exercise, Control
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Salisbury University
Preeclampsia and Eclampsia, Stiffness, Aortic
Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery
The investigator measured the arterial stiffness using cardio-ankle vascular index (CAVI) test in patient with preeclampsia and normal pregnant women to evaluate the longitudinal change of CAVI and their predictors.
- Conditions
- Preeclampsia and Eclampsia, Stiffness, Aortic, Blood Pressure
- Trial name
- NCT04142268
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Obesity
Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest
This study investigated if elevated BP and aortic stiffness characterized in obese individuals are attenuated following acute grape seed extract supplementation.
- Trial name
- NCT04389060
- Testing
- Grape seed extract
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Pressor Response, Baroreflex Sensitivity
High Resolution Phenotyping in Healthy Humans
Baroreflex sensitivity is integral to blood pressure regulation, and varies among healthy, normotensive individuals. A reduced compensatory ability of baroreflex buffering in patients with carotid denervation results in blood…
- Conditions
- Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability
- Trial name
- NCT00943774
- Testing
- Physiological maneuvers
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypertension, Insulin Resistance Syndrome
Cf-PWV and TyG Index Study
This study aims to investigate how metabolic health is related to arterial stiffness and daily blood pressure patterns. High blood pressure is one of the leading causes of heart disease worldwide, but cardiovascular risk is not…
- Conditions
- Hypertension, Insulin Resistance Syndrome, Arterial Stiffness, Cardiovascular Risk
- Trial name
- RIGID-TyG (NCT07589374)
- Where
- Brazil
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Arterial Stiffness, Blood Pressure
Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women
The goal of this clinical trial is to assess the impact of table grape consumption on gut microbiome, intestinal permeability, systemic inflammation, and vascular function in healthy overweight men and women aged 45-70 years.
- Conditions
- Arterial Stiffness, Blood Pressure, Dysbiosis, Inflammation
- Trial name
- CALGRAM (NCT06544954)
- Testing
- Freeze-dried grape powder
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sedentary Behavior
Effect of Cocoa Supplementation and Aerobic Exercise on Pressure Parameters
This study evaluates the cocoa supplementation and aerobic exercise on central pressure and arterial stiffness parameters in physically inactive middle-aged individuals. 500mg capsules will be offered to all patients.
- Trial name
- NCT04732754
- Testing
- Aerobic exercise + Theobroma cocoa (AETC), Control Group (CG), Aerobic Exercise (AE)
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Healthy
Daily Intake of Cocoa Flavanols and Arterial Stiffness in Humans
A randomized, double-masked and cross-over dietary intervention study to investigate the effects of diet supplementation with cocoa flavanols on arterial stiffness in healthy adult human subjects.
- Trial name
- NCT03587883
- Testing
- Cocoa flavanols I, Control I, Cocoa flavanols II
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Hypertension, Aging
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased…
- Trial name
- NCT03821623
- Testing
- Nicotinamide riboside
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Douglas Seals
Hypertension
Beetroot Enriched Bread, Blood Pressure and Vascular Function
Dietary nitrate is known to lower blood pressure. Beetroot is a rich source of nitrate and could therefore be an important dietary component in the management of hypertension and cardiovascular disease, however consumption is…
- Trial name
- NCT01706718
- Testing
- Bread
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Reading
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure
Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses
To test the effect of limb occlusion pressure attainment in the supine, seated, and standing position on exercise performance, vascular physiology, and muscle.
- Conditions
- Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
- Trial name
- NCT06718582
- Testing
- Delfi Training Device
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Teri Herberger
Blood Pressure
The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness
The goal of this clinical trial is to examine the effect of short-term L-Citrulline on central and peripheral blood pressure in healthy older adults.
- Trial name
- NCT05974813
- Testing
- L-Citrulline
- Where
- Cyprus
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- European University Cyprus
Aging, Blood Pressure
Coconut Sugar Lowers Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
The goal of this intervention is to determine the efficacy of coconut sap powder (CSP) to lower arterial stiffness and blood pressure in middle-aged and older adults.
- Conditions
- Aging, Blood Pressure, Arterial Stiffness
- Trial name
- NCT05645991
- Testing
- Coconut Sap Powder (CSP)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ball State University
Cardiovascular Disease, Aging
Effects of Age and Exercise on Blood Pressure Regulation
The purpose of this study is to investigate the effects of age, exercise and cardiovascular disease on blood pressure.
- Trial name
- NCT00319397
- Testing
- Exercise-Training Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Cardiovascular Disease
Diet and Vascular Health Study
The aim of this study is to examine the effects of a diet rich in broccoli on cardiovascular disease risk using biochemical indicators such as blood lipid profiles, most notably cholesterol; markers of inflammation as well as…
- Trial name
- BROCCOLI (NCT01114399)
- Testing
- Diet and Vascular Health, Diet and Vascular Health Study
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Blood Pressure, Arterial Stiffness
Comparison of Different Non-invasive Methods to Assess Pulse Wave Analysis
The primary goal of the study is to compare different methods for pulse wave measurement and analysis which are cuffless and contactless. The novel measurement tools will be compared to cuff-based reference methods.
- Conditions
- Blood Pressure, Arterial Stiffness, Arrythmia
- Trial name
- MULTI-PWA (NCT05790642)
- Testing
- Pulse wave measurement and analysis
- Where
- Germany
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Healthy
Acute Effect of Nitrate From Natural Dietary Sources on Arterial Stiffness and Blood Pressures in Healthy Individuals
The purpose of this study is to evaluate the acute effect of a meal high in dietary nitrates on aortic augmentation index, brachial and aortic blood pressures, and subendocardial viability ration (SEVR).
- Trial name
- DNAB (NCT01604993)
- Testing
- Spinach soup, Asparagus soup
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto