Clinical trials: Arteriovenous Fistula
Renal Dialysis, Hemodynamics
The LIPMAT Study: Liposomal Prednisolone to Improve Hemodialysis Fistula Maturation
This study will investigate if liposomal prednisolone is effective in promoting arteriovenous fistula (AVF) maturation when administered to human subjects after surgical creation of a radio-cephalic AVF.
- Conditions
- Renal Dialysis, Hemodynamics, Vascular Remodeling, Neointima
- Trial name
- LIPMAT (NCT02495662)
- Testing
- PEG-liposomal prednisolone sodium phosphate
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Kidney Failure, Chronic
Creation of Arteriovenous Ante-brachial Fistula Under Axillary Block Versus Local Anesthesia : Impact on Early Complications
Recommended by the KDOQI vascular access guidelines, antebrachial arteriovenous fistula is the best primary vascular access for hemodialysis in patients with end stage renal disease.
- Trial name
- FAV ss ALR (NCT02722096)
- Testing
- Axillary block anesthesia with Ropivacaine and Lidocaine, Local anesthesia with Ropivacaine and Lidocaine
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Hospices Civils de Lyon
End-stage Renal Disease (ESRD)
Creating a Buttonhole Tunnel Track by Repeated Needling of the AV Fistula on the Same Day in Patients on Hemodialysis.
BACKGROUND: The patients diagnosed with end stage renal disease require dialysis and for that they need to have a vascular access for hemodialysis (HD) placed.
- Trial name
- NCT03989141
- Testing
- Repeated cannulation Buttonhole., Single cannulation Buttonhole.
- Where
- 2 sites in Denmark
- Volunteers
- 43 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Pain, Cannula Site Pain
Impact of Stress Balls on Cannulation Pain in Hemodialysis: A Randomized Study
Background: Chronic kidney disease significantly impacts patients and their families, with a portion requiring hemodialysis. Hemodialysis involves repeated vascular cannulation, often causing moderate to severe pain.
- Trial name
- NCT06237738
- Testing
- Stress Ball Use
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Hasan Kalyoncu University
Arteriovenous Fistula
Exercise Program for Arteriovenous Fistula Maturation
Arteriovenous fistula (AVF) is the recommended vascular access for chronic hemodialysis, as it is associated with less mortality and better patency than arteriovenous graft (AVG) or central venous catheter (CVC).
- Trial name
- FAVULOUS (NCT04034433)
- Testing
- Handgrip exercise program
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Diseases, Renal Failure
Advanced Ultrasound Applications for Predicting AVF Outcomes
Haemodialysis is a renal replacement therapy that can be introduced to patients with end-stage renal disease (ESRD) to help them maintain a good healthy life.
- Conditions
- End Stage Renal Diseases, Renal Failure, Chronic Kidney Diseases
- Trial name
- AUAPAVFO (NCT04141358)
- Testing
- Advanced ultrasound measurements
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Arterio-venous Fistula
Anchor Versus Parachute Suturing Technique in Arteriovenous Fistula Creation for Hemodialysis
Randomized controlled study to compare the results of two surgical techniques for AVF creation, including the anchor technique (Group A) and parachute technique (Group B).
- Trial name
- NCT06091839
- Testing
- suturing technique in arteriovenous fistula creation for hemodialysis
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
End Stage Renal Disease, Hemodialysis Vascular Access Failure
Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients
The primary purpose of this pilot study is to assess the pharmacokinetic profile of low-dose bevacizumab and its effectiveness in reducing plasma free VEGF-A levels safely in hemodialysis patients.
- Trial name
- NCT02695641
- Testing
- 1.25mg bevacizumab, 2.50mg bevacizumab
- Sponsor
- Mayo Clinic
Venous Stenosis, Venous Occlusion
The Merit WRAPSODY AV Access Efficacy Study (WAVE)
The purpose of the study is to demonstrate the safety and efficacy of the Merit WRAPSODY Endovascular Stent Graft for treatment of stenosis or occlusion within the dialysis access outflow circuit
- Trial name
- WAVE (NCT04540302)
- Testing
- Merit WRAPSODY Endovascular Stent Graft, PTA
- Where
- 43 sites in United States, Brazil and 2 more
- Volunteers
- 357 people
- Sponsor
- Merit Medical Systems, Inc.
Chronic Kidney Disease 5D, Heart Failure
Cardio-fistular Recirculation in Patients With Chronic Heart Failure and Preserved Left Ventricle Ejection Fraction
This is a single-arm cohort study aimed to evaluate change of arteriovenous fistula volume blood flow / cardiac output ratio in patients with chronic heart failure (NYHA I-II classes) and with preserved ejection fraction as a…
- Conditions
- Chronic Kidney Disease 5D, Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II
- Trial name
- NCT06394986
- Testing
- Hemodialysis session
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Cardio-cerebral Vascular Events, Arteriovenous Fistula Dysfunction
Impact and Mechanism of Depression on Cardio-cerebral Vascular Events and Arteriovenous Fistula Dysfunction in MHD Patients
Depression is a common psychiatric disorder in patients on maintenance hemodialysis (MHD). It may contribute to poor prognosis in a number of ways, including its effect on platelet function.
- Trial name
- NCT06070805
- Testing
- depression
- Where
- China
- Volunteers
- 286 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
End Stage Renal Disease, Arteriovenous Fistula
Role of Monocytes Adhesion and Vascular Lesions in Vascular Access Success or Failure in Uremic Patients
This study is designed to identify novel predictors of vascular access success or failure in chronic kidney disease patients. Despite efforts to improve placement of arteriovenous fistula (AVF) the primary failure rates are…
- Trial name
- ROMAVAS (NCT03231410)
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Arteriovenous Fistula, Arteriovenous Graft
FLEX FIRST Registry Research Protocol
Prospective, observational study evaluating the clinical use and outcomes of the FLEX Vessel Prep (VP) system in arteriovenous fistulae or grafts presenting with clinical or hemodynamic abnormalities following 12 months post…
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Fistula, Arterial Occlusive Diseases
- Trial name
- NCT05616104
- Testing
- FLEX Vessel Prep System
- Where
- 4 sites in United States
- Volunteers
- 130 people
- Sponsor
- VentureMed Group Inc.
Chronic Kidney Disease (CKD)
A Prospective Clinical Evaluation of the Total Vascular Access (TVA) FLEX-1 Device Protocol Flex-1-002-IR Intervention Reduction (IR)
The primary objective of this clinical study is to evaluate the preliminary safety and effectiveness of using the FLEX-1 device for the creation of an arteriovenous fistula (AVF) including coiling of the brachial vein during the…
- Trial name
- NCT02119832
- Testing
- Endovasccular AVF (EndoAVF)
- Where
- Paraguay
- Volunteers
- 17 people
- Sponsor
- C. R. Bard
Angioplasty, Stenosis of Arteriovenous Fistula
Paclitaxel-coated Balloon Angioplasty Versus Standard Angioplasty for the Treatment of Stenosis of Arteriovenous Fistula
The primary objective of this double-blind study is to compare the frequency of primary patency at 6 months in patients with stenosis of arteriovenous fistula (AVF) treated either by conventional angioplasty + angioplasty with…
- Trial name
- ABISS (NCT02753998)
- Testing
- Additional angioplasty with paclitaxel-coated balloon, Conventional angioplasty
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Arteriovenous Fistula
Breathing Exercise and Invasive Pain at Hemodialysis Patients
Non-pharmacological approaches applied in the prevention of invasive pain due to cannulation in patients treated with arteriovenous fistula and hemodialysis; It is also a cost-effective method that prevents the patient from…
- Conditions
- Pain, Arteriovenous Fistula, Breathing Exercise
- Trial name
- NCT05252377
- Testing
- Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Demiroglu Bilim University
Stenosis of Arteriovenous Dialysis Fistula
Arteriovenous Fistula: Conventional Angioplasty vs Drug Eluting Balloon-assisted Maturation Intervention Clinical Trial
The purpose of this randomised clinical trial is to evaluate the efficacy of drug-eluting balloon compared to conventional balloon in balloon-assisted maturation of non-maturing arteriovenous fistula in adult renal failure…
- Trial name
- ACADEMIC (NCT03068845)
- Testing
- Drug-eluting balloon angioplasty (DEBA), Conventional Balloon Angioplasty (CBA)
- Volunteers
- 124 people
- Sponsor
- Singapore General Hospital
End-stage Renal Disease
Evaluation of the Radial Artery Deviation And Reimplantation Technique for Primary Hemodialysis Access Creation
The Radial Artery Deviation And Reimplantation (RADAR) technique is a new approach for the construction of hemodialysis arteriovenous fistula.
- Trial name
- RADAR (NCT02728817)
- Testing
- End-cephalic vein to side-radial artery fistula creation, RADAR fistula creation
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Fistulas Arteriovenous
Radiation Free Fistuloplasty is the Way Forward
The goal of this clinical trial is to study effectiveness of ultrasound-guided fistuloplasty in comparison to conventional fistuloplasty in patients with arteriovenous access flow dysfunction.
- Trial name
- NCT06480331
- Testing
- Ultrasound-guided fistuloplasty, Fluoroscopy-guided fistuloplasty
- Where
- 2 sites in Malaysia
- Volunteers
- 54 people
- Sponsor
- University of Malaya