Clinical trials: Artery Disease, Peripheral
Limb Ischemia
Nanofat Grafting as a Method of Treating Critical Limb Ischemia
This clinical trial will investigate nano fat grafting as a method for treating critical limb ischemia. The method involves the collection of adipose tissue under tumescent anesthesia through a separate incision in the anterior…
- Trial name
- NCT06357936
- Testing
- nano-fat grafting in chronic limb ischaemia
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Center of New Medical Technologies
Peripheral Arterial Disease
The IMPACT PAD Study
Defining the role of intraprocedural physiology measurements in peripheral endovascular treatment
- Trial name
- IMPACT PAD (NCT05035771)
- Testing
- Pressure wire measurement in peripheral vascular disease
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Peripheral Arterial Disease
Use of Indocyanine Green Angiography in Critical Limb Ischemia
Investigators conduct a monocentric pilot study with the objective to determine the hemodynamic parameter of fluorescence angiography (slope, amplitude, saturation time ) best correlated with toe pressure in patients with…
- Trial name
- FLUORESCENCE (NCT02820467)
- Testing
- fluorescence angiography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Peripheral Arterial Disease
MyPADMGT Support of Out-Patients With Peripheral Arterial Disease
The investigators have developed an online program to help people with peripheral arterial disease (PAD) in their extremities to better self-manage their condition.
- Trial name
- Final_PADHSS (NCT04228549)
- Testing
- MyPADMGT, MyPADMGT + Nudging
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- McMaster University
Atherosclerosis of the Peripheral Arteries
Pilot Randomized Clinical Study of the Iliac Arteries and Common Femoral Artery With Stenting and the Iliac Arteries With Stenting and Plasty of the Common Femoral Artery
According to the recommendations of the Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II) statement and the Russian guidelines for limb ischemia treatment (2010), reconstructive surgery is…
- Trial name
- TASC CD (NCT03315884)
- Testing
- Iliac segment recanalization and stenting Iliac segment Common Femoral Artery (CFA), Iliac segment recanalization, stenting and plastic Common Femoral Artery (CFA) patch
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Limb Ischemia, Low Back Pain
Comorbidity Screening and Referral by Prosthetists
Lower-limb amputation is associated with life-altering and life-limiting comorbidities. Currently, onus is on primary care providers to diagnose, educate, and refer patients for appropriate management.
- Conditions
- Limb Ischemia, Low Back Pain, Depression, Neuropathy;Peripheral
- Trial name
- NCT05410548
- Testing
- Standard-of-Care, Clinical Screening
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Delaware
Peripheral Artery Disease, Peripheral Vascular Disease
Evaluation of an Electronic Health Record-based Screening Tool for Peripheral Artery Disease
This protocol represents a pilot randomized-controlled trial evaluating the effect of an electronic health record (EHR)-based peripheral artery disease (PAD) screening tool on rates of new non-invasive testing, diagnosis and…
- Trial name
- NCT04054232
- Testing
- High PAD risk Alert
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Diabetes Mellitus, Critical Limb Ischemia
Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia
The ECAD-CLI is an investigator-driven, prospective, single-center study. The aim of the study is to prospectively collect clinical, laboratory, angiographic, cellular and molecular variables related to prognosis and outcome in…
- Conditions
- Diabetes Mellitus, Critical Limb Ischemia, Critical Lower Limb Ischemia, Diabetic Foot
- Trial name
- ECAD-CLI (NCT03636867)
- Testing
- data and specimen collection
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- Maria Cecilia Hospital
Claudication, Peripheral Artery Disease
The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
This study is a 3-month, prospective, randomized controlled clinical trial designed to address the efficacy of the DASH dietary program combined with a home-based exercise program, quantified by a step activity monitor, to…
- Trial name
- NCT03845036
- Testing
- DASH Diet plus Home-Based Exercise, Home-Based Exercise
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oklahoma
Angioplasty, Peripheral Arterial Disease
Safety and Effectiveness Evaluation of iCover Covered Stent for the Treatment of the Aorto-iliac Occlusive Disease
The objective of this prospective, multi-center, non-randomized, single-arm observational study is to evaluate the safety and the efficacy of the iCover covered stent over a 24-month follow-up period for the treatment of de novo…
- Conditions
- Angioplasty, Peripheral Arterial Disease, Iliac Artery Disease, Covered Stent
- Trial name
- iliCo (NCT05192616)
- Testing
- Covered stent implantation
- Where
- 18 sites in Belgium, France and 2 more
- Volunteers
- 241 people
- Sponsor
- iVascular S.L.U.
Intermittent Claudication
Home-based Exercice Therapy for Patients With Intermittent Claudication Using a New Smartphone Application
The main characteristic of PAD is to limit physical activity by the appearance of claudication of the lower limbs which limits the walking distance, or the maximum distance traveled by the patient before the pain forces to stop.
- Trial name
- APAISE (NCT05457738)
- Testing
- E-REVA® app, No E-REVA® app
- Where
- France
- Volunteers
- 52 people
- Sponsor
- CHU de Reims
Peripheral Arterial Disease
"Unifuzol®" in Patients With Peripheral Arterial Disease
The present study is a multicenter, randomized, double-blind, placebo-controlled study of the safety and efficacy of the drug Unifuzol® (L-arginine) in patients with obliterating atherosclerosis of the lower extremities.
- Trial name
- NCT03861416
- Testing
- L-arginine 1.4% 500 ml
- Where
- 19 sites in Russia
- Volunteers
- 360 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Spinal Stenosis Lumbar, Low Back Pain
Validation of a Treadmill Walking Test to Discriminate Neurogenic Claudication From Vascular Claudication
The first aim of this study was to elaborate and validate a treadmill walking test that would help discriminate between neurogenic claudication from vascular claudication.
- Conditions
- Spinal Stenosis Lumbar, Low Back Pain, Peripheral Artery Disease, Claudication
- Trial name
- NCT04058171
- Testing
- Treadmill walking test
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Université du Québec à Trois-Rivières
Peripheral Vascular Diseases
A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)
A 12-Week Efficacy Study in participants with Peripheral Arterial Disease. the primary hypothesis is that MK-0736 7 mg administered once daily for 12 weeks will result in a decrease in lower extremity atherosclerotic plaque…
- Trial name
- NCT00679055
- Testing
- MK-0736
- Volunteers
- 14 people
- Sponsor
- Merck Sharp & Dohme LLC
Peripheral Vascular Diseases
Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease
Atherosclerosis, a condition in which fatty deposits build up along the inner walls of arteries, can occur throughout the body. The purpose of this study is to examine the possible genetic differences that may influence where…
- Trial name
- GenePAD (NCT00380185)
- Where
- 2 sites in United States
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- Stanford University
Peripheral Arterial Disease
The AbsorbaSeal Vascular Closure Device Trial
This study investigates the efficacy and safety of the AbsorbaSeal 6Fr Vascular Closure device (VCD) for the closure of access site of patients requiring percutaneous diagnostic or interventional procedures.
- Trial name
- NCT03730571
- Testing
- AbsorbaSeal 6Fr Vascular Closure Device
- Where
- 3 sites in Belgium
- Volunteers
- 9 people
- Sponsor
- ID3 Medical
Peripheral Arterial Disease
Kaitoh Atherectomy FIH
This is a prospective, multi-center and single-arm clinical study to assess the initial safety and effectiveness of the Kaitoh Atherectomy System for the treatment of de novo and/or restenotic lesion(s) in the peripheral arteries.
- Trial name
- NCT05873452
- Testing
- Kaitoh Atherectomy System
- Where
- 2 sites in New Zealand
- Volunteers
- 9 people
- Sponsor
- Terumo Medical Corporation
Intermittent Claudication
The PaWS (Pedometer and Walking Study)
The literature has shown that supervised exercise programs for patients with PAD and who report intermittent claudication (IC) have improved health outcomes, but this is not locally available.
- Trial name
- PAWS (NCT02510807)
- Testing
- Pedometer
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Diabetic Foot, Peripheral Arterial Disease
Microwave Radiometry Thermometry for the Diagnosis of Critical Limb Ischemia in Diabetic Patients
Diagnosis of vascular involvement in diabetic foot disease remains challenging. Differential diagnosis between pure neuropathic or neuro-ischemic diabetic foot requires a combination of clinical examination, medical history and…
- Conditions
- Diabetic Foot, Peripheral Arterial Disease, Ischaemic Neuropathy
- Trial name
- NCT03002116
- Testing
- Tissue thermometry using non-invasive microwave radiometry device
- Where
- 3 sites in Greece, United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Attikon Hospital
Peripheral Artery Disease, Hypertension
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
This is a 26-week, prospective double-blind, randomized pilot trial of nebivolol versus an active control, metoprolol succinate, in patients with established lower-extremity peripheral artery disease, hypertension, and at least…
- Trial name
- ENCOMPASS (NCT01499134)
- Testing
- nebivolol, Metoprolol succinate
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Thomas Jefferson University