Clinical trials: Artery Disease, Peripheral
Peripheral Artery Disease
Evaluation of Patients With Suspected Endofibrosis
Define responses to exercise on both arterial bruits and oxymetry in patients referred for suspected endofibrosis.
- Trial name
- Stethosport (NCT02501694)
- Testing
- Auscultation
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Critical Limb Ischemia
Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation
Drug-eluting balloon showed positive results in terms of restenosis reduction in peripheral intervention (PTA). The aim of the study is to investigate in a randomized fashion the efficacy and safety of Paclitaxel-eluting balloon…
- Trial name
- DEBATE-BTK (NCT01558505)
- Testing
- PEB, POBA
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- Leonardo Bolognese, MD
Peripheral Arterial Disease, Lower Extremity Arterial Disease
Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries
This study will test whether using ultrasound imaging within blood vessels during minimally invasive treatment of leg arteries in patients with peripheral artery disease leads to better clinical outcomes.
- Trial name
- INVIGOR (NCT07353905)
- Testing
- Intravascular Ultrasound (IVUS), Angiographic-guided Intervention
- Where
- 6 sites in United States
- Volunteers
- 350 people
- Sponsor
- Baylor Research Institute
Peripheral Artery Disease, PAD
A Study to Evaluate the Effect of Sarpogrelate on Blood Hyperviscosity
This study is to evaluate the effect of sarpogrelate on blood viscosity after 24 weeks in patients with high blood viscosity.
- Trial name
- NCT03509922
- Testing
- Anplag Tab. 100mg bid, Anplag Tab. 100mg tid
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yuhan Corporation
Atherosclerosis
Study Comparing Legflow Versus Bare Balloon Angioplasty for Treatment of Atherosclerotic Disease
A randomized multicentric study for endovascular treatment of patients with obstructive disease in the SFA (superficial femoral artery) and in the popliteal artery.
- Trial name
- NCT02710656
- Testing
- Legflow® balloon, Standard PTA
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 130 people
- Sponsor
- Cardionovum GmbH
Chronic Kidney Disease Stage 3 and 4, Peripheral Artery Disease (PAD)
Exercise Activity to Improve Mobility in Patients With CKD and PAD
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.
- Trial name
- EXACT-CKDPAD (NCT06621264)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control (Standard treatment)
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Peripheral Artery Disease, Diabetes Mellitus
The Application of Digital Infrared Thermal Imaging in Peripheral Artery Disease of the Lower Extremities
Peripheral artery disease (PAD) is highly prevalent. It occurs most often in the lower extremities. Symptoms include intermittent claudication, ischemic pain, ulceration and necrosis. Amputation may be necessary in severe cases.
- Trial name
- NCT02783677
- Testing
- Percutaneous balloon angioplasty
- Where
- Taiwan
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Critical Limb Ischemia
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.
This study will evaluate the efficacy and safety of apixaban 2.5 mg twice daily plus aspirin compared to the standard treatment (clopidogrel plus aspirin) in patients with critical limb ischemia undergoing infrapopliteal arterial…
- Trial name
- AGRIPPA (NCT04229264)
- Testing
- Apixaban, ASA, Clopidogrel 75mg
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Science Valley Research Institute
Peripheral Arterial Occlusive Disease
"All Comers" Post Market Clinical Follow-up (PMCF) With Multi-LOC for flOw liMiting Outcomes
The aim of the study is to assess the safety and efficacy of the Multi-LOC® peripheral stent system to treat de novo and restenotic lesions (no in-stent restenosis (ISR), no restenosis post drug coated balloon (DCB) after flow…
- Trial name
- LOCOMOTIVE (NCT02531230)
- Testing
- VascuFlex Multi-LOC®
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- B. Braun Melsungen AG
Peripheral Artery Disease
SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
Open label, real-world, prospective, multi-center, single arm, post-market surveillance study of the SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB).
- Trial name
- SUCCESS PTA (NCT04776434)
- Testing
- SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB)
- Where
- 27 sites in Argentina, Germany and 6 more
- Volunteers
- 723 people
- Sponsor
- M.A. Med Alliance S.A.
Atherosclerosis, Intermittent Claudication
Does the Reduction of Total Body Iron Storage (TBIS) Alter Mortality in a Population of Patients With Advanced PVD?
Veterans Affairs Cooperative Study #410, The Iron and Atherosclerosis Trial, FeAST, a 24-hospital prospective randomized single-blinded clinical trial of graded iron reduction was conducted between May 1, 1999 and April 30, 2005…
- Conditions
- Atherosclerosis, Intermittent Claudication, Peripheral Vascular Diseases
- Trial name
- FeAST (NCT00032357)
- Testing
- Ferritin reduction to 25 ng/ml by phlebotomy
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 1,277 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Peripheral Arterial Disease
Effect of Polyphenols on Peripheral Vascular Disease.
Peripheral arterial disease (PAD) is a clinical setting characterized by an exceptionally high risk for cardiovascular events. Oxidative stress seems to play a role in impairing flow-mediated dilation (FMD) and contributing to…
- Trial name
- NCT01947712
- Testing
- dark chocolate with crossover to milk chocolate, milk chocolate with crossover to dark chocolate
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Peripheral Arterial Disease
BRAVO: Biomarker Risk Assessment in Vulnerable Outpatients
The investigators hypothesize that among people with lower extremity peripheral artery disease (PAD), biomarker levels are higher during time periods immediately preceding an acute coronary event compared to time periods not…
- Trial name
- BRAVO (NCT02276781)
- Where
- 6 sites in United States
- Volunteers
- 595 people
- Sponsor
- Northwestern University
Limb Ischemia
Nanofat Grafting as a Method of Treating Critical Limb Ischemia
This clinical trial will investigate nano fat grafting as a method for treating critical limb ischemia. The method involves the collection of adipose tissue under tumescent anesthesia through a separate incision in the anterior…
- Trial name
- NCT06357936
- Testing
- nano-fat grafting in chronic limb ischaemia
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Center of New Medical Technologies
Peripheral Artery Disease
Exercise Training Versus Best Medical Treatment Only in Peripheral Artery Disease
The aim of the investigators' study is to analyze the value of supervised exercise training combined with medical therapy versus best medical treatment only with respect to quality of life.
- Trial name
- NCT00926081
- Testing
- Supervised exercise training
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Critical Limb Ischemia
Study of the Clinical Efficacy of Autologous SCT in Patients With Critical Limb Ischemia
Phase II Prospective Study of the Clinical Efficacy of Autologous SCT in patients with Critical Limb Ischemia
- Trial name
- NCT01311011
- Testing
- SCT
- Where
- Saudi Arabia
- Volunteers
- 26 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Peripheral Arterial Disease
Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries
The Auryon Laser Atherectomy System has been cleared by the FDA to treat infrainguinal arterial disease including in-stent restenosis
- Trial name
- NCT05284240
- Testing
- Auryon Laser System
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Midwest Cardiovascular Research Foundation
Peripheral Artery Disease
Bard LifeStent and Lutonix DCB for Treatment of Long Lesions in Femoropopliteal Arteries
Objective of this study is to evaluate the safety and efficacy of Lutonix 035 Drug Coated Dilatation PTA Catheter with Bard LifeStent Vascular Stent (hereinafter referred to as LifeStent) for treatment of long (10-24 cm) lesions…
- Trial name
- NCT02278991
- Testing
- Lutonix Drug Coated Balloon
- Where
- 12 sites in Germany, Greece and 1 more
- Volunteers
- 149 people
- Sponsor
- C. R. Bard
Peripheral Arterial Disease
Vitamin D and Walking Ability in Patients With Peripheral Artery Occlusive Disease
The purpose of this study is to determine whether the intake of Vitamin D has a positive effect on walking ability of patients with peripheral artery occlusive disease.
- Trial name
- NCT01559974
- Testing
- Cholecalciferol
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University Hospital, Basel, Switzerland
Peripheral Arterial Disease
Telerehabilitation in Patients With Peripheral Arterial Disease
This prospective longitudinal study evaluated the feasibility, adherence, and clinical and functional effects of a 6-month home-based telerehabilitation program in patients with peripheral arterial disease of the lower limbs.
- Trial name
- PAD_TR (NCT07825168)
- Testing
- Home-based telerehabilitation
- Where
- Romania
- Volunteers
- 42 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
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