Clinical trials: Artery Stenosis
Femoral Artery Stenosis, Popliteal Artery Stenosis
IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery (SFA) and Proximal Popliteal Artery (PPA)
The purpose of the study is to demonstrate the safety and efficacy of the IN.PACT Admiral drug-coated balloon (DCB) in comparison to any standard balloon for treatment of peripheral arterial disease (PAD) in the superficial…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- INPACT SFA II (NCT01566461)
- Testing
- Drug-Coated Balloon (DCB), PTA Balloon: Balloon Angioplasty
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Medtronic Endovascular
ST Elevation Myocardial Infarction, Multi-Vessel Coronary Artery Stenosis
Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease
About half of patients with ST-segment elevation myocardial infarction (STEMI) have multi-vessel lesions (> 50% diameter stenosis). But how to deal with the non-culprit vessels is still controversial.
- Trial name
- NCT04259853
- Testing
- PCI
- Where
- 15 sites in China
- Volunteers
- 1,016 people
- Sponsor
- Fujian Medical University
Carotid Stenosis, Coronary Stenosis
Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease
The purpose of this study is to evaluate the potential benefit of systematic preoperative coronary angiography followed by selective coronary artery revascularization on the incidence of myocardial infarction (MI) in patients…
- Trial name
- CACEA (NCT02260453)
- Testing
- Preoperative coronary angiography, Standard cardiac workup
- Volunteers
- 426 people
- Sponsor
- University of Roma La Sapienza
Coronary Artery Disease, Coronary Restenosis
DEB Versus 2nd Generation DES in Patients With In-Scaffold Restenosis of Bioresorbable Vascular Scaffold
The aim of the study is to compare angiographic outcomes following revascularization using drug-eluting balloon (DEB) versus 2nd generation drug-eluting stent (DES) in treatment of Bioresorbable Vascular Scaffold Restenosis.
- Trial name
- SMART-BRS-ISR (NCT03074305)
- Testing
- PCI for in-bioresorbable scaffold stenosis
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Carotid Stenosis, Carotid Artery Disease
The MICHI NEUROPROTECTION SYSTEM: Evaluation of Performance in Carotid Artery Stent Procedures (The LOTUS Study)
The LOTUS Study is intended to demonstrate the usability of the MICHI Neuroprotection System (MICHI NPS) or MICHI Neuroprotection System with filter (MICHI NPS+f) for use in subjects who are candidates for Carotid Artery Stenting…
- Trial name
- LOTUS (NCT01958294)
- Testing
- MICHI Neuroprotection System
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Silk Road Medical
Atherosclerosis
Intensive Rosuvastatin Therapy on Cerebral Hemodynamics in Patients With Atherosclerotic Intracranial Arterial Stenosis
Atherosclerotic intracranial arterial stenosis (AICAS) corresponds to luminal narrowing of the major intracranial arteries. The prevalence of intracranial atherosclerotic stenosis accounts for 33% to 67% of stroke or transient…
- Trial name
- NCT02594800
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Carotid Artery Stenosis
Safety and Efficacy of the CGuard™ Carotid Stent System in Carotid Artery Stenting
The objective of this pivotal study is to evaluate the safety and efficacy of the CGuard™ Carotid Stent System in the treatment of carotid artery stenosis in symptomatic and asymptomatic patients undergoing carotid artery…
- Trial name
- C-Guardians (NCT04900844)
- Testing
- CGuard Carotid Stent implantation
- Where
- 18 sites in United States, Poland
- Volunteers
- 317 people
- Sponsor
- InspireMD
Cerebrovascular Disease
Tissue Kallikrein Preventing the Restenosis After Stenting of Symptomatic MCA Atherosclerotic Stenosis
The study aims to determine whether tissue kallikrein (TK) is efficacy for preventing the long-term in-stent restenosis (ISR) after stenting of symptomatic atherosclerotic stenosis of the middle cerebral artery (MCA) M1 segment
- Trial name
- NCT01558245
- Testing
- tissue kallikrein
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Jinling Hospital, China
Refractory Angina Pectoris, Ischemic Heart Disease
Cardiac Shock Wave Treatment in Patients With Reduced Coronary Flow Reserve
The purpose of the study is to assess the feasibility of Cardiac Shock Wave Treatment in patients with anginal chest pain and evidence of abnormal myocardial perfusion under stress in the absence of significant stenoses of the…
- Conditions
- Refractory Angina Pectoris, Ischemic Heart Disease, Coronary Artery Disease
- Trial name
- NCT03438500
- Testing
- Cardiac Extracorporeal Shockwave Therapy (Modulith SLC)
- Where
- Germany
- Sponsor
- Storz Medical AG
Coronary Artery Disease, Everolimus
SPIRIT FIRST Clinical Trial of the Abbott Vascular XIENCE V® Everolimus Eluting Coronary Stent System
Prospective, randomized, controlled, single-blinded, parallel two-arm, multicenter trial. Test arm: XIENCE V® Everolimus Eluting Coronary Stent System(stent length: 18mm, diameter: 3.0mm) Control arm: Metallic stent (MULTI-LINK…
- Conditions
- Coronary Artery Disease, Everolimus, Vascular Disease, Myocardial Ischemia
- Trial name
- NCT00180453
- Testing
- Coronary artery drug eluting stent placement, Coronary artery stent placement
- Where
- 7 sites in Denmark, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease
The Nordic Bifurcation Study III
Should we, or should we not, perform dilatation of the side branch through the main vessel stent, if there is acceptable blood flow in the side branch?
- Trial name
- BIF III (NCT00914199)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Denmark
- Volunteers
- 477 people
- Sponsor
- Evald Hoej Christiansen
Carotid Stenosis
Clopidogrel Resistance and Embolism in Carotid Artery Stenting
The purpose of this study is to evaluate the efficacy and safety of the ticlopidine + ginko biloba compared to clopidogrel in clopidogrel resistant patients undergoing carotid artery stent placement.
- Trial name
- CRECAS (NCT02133989)
- Testing
- Ticlopidine + Ginko biloba, Clopidogrel
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Coronary Artery Stenosis, Coronary Artery Disease
HanYang University Medical Center (HYUMC) Registry
The HYUMC registry is a two-center, real-world registry of percutaneous coronary intervention in patients with coronary artery disease.
- Conditions
- Coronary Artery Stenosis, Coronary Artery Disease, Blood Pressure
- Trial name
- HYUMC (NCT05935397)
- Testing
- percutaneous coronary intervention
- Where
- 3 sites in South Korea
- Volunteers
- 5,000 people
- Sponsor
- Hanyang University Seoul Hospital
Carotid Atherosclerosis, Carotid Stenosis
Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
The aim is to compare the safety of using transfemoral and transradial approach in patient undergoing carotid arteries stenting.
- Conditions
- Carotid Atherosclerosis, Carotid Stenosis, Ischemic Attack, Stroke
- Trial name
- NCT02722720
- Testing
- Transradial carotid artery stenting, Transfemoral carotid artery stenting
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Renal Artery Stenosis
Identification and Treatment of Renal Stenosis in Transplanted Kidneys
Renal artery stenosis is a complication that may follow kidney transplantation1-5. Renal artery stenosis greater than 50% of the lumen of the artery, associated with clinical symptoms or laboratory worsening of renal function…
- Trial name
- TRAS (NCT06822205)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Erectile Dysfunction, Peripheral Arterial Disease
Selution Sirolimus-eluting Balloon for Internal Pudendal-penile Artery Disease-related Erectile Dysfunction
According to epidemiological surveys in various countries around the world, the prevalence of erectile dysfunction in men over the age of 40 is about 40%.
- Conditions
- Erectile Dysfunction, Peripheral Arterial Disease, Arterial Stenosis
- Trial name
- NCT05362994
- Testing
- Selution SLR™ sirolimus-eluting balloon, Plain old balloon angioplasty
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- National Taiwan University Hospital
Coronary Artery Disease
Impact of Coronary CT Angiography, Physiologic Assessment and Pharmacotherapy on the Clinical Outcomes
The investigators aim to investigate the prognostic implication of stenosis and plaque features on coronary CT angiography (CCTA), physiologic assessment, and pharmacotherapy after invasive coronary angiography.
- Trial name
- PRIME-CT (NCT04547231)
- Testing
- Fractional flow reserve, Coronary CT angiography
- Where
- South Korea
- Volunteers
- 992 people
- Sponsor
- Seoul National University Hospital
Post-operative Craniotomy Patients, Carotid Endarterectomy and Carotid Artery Stenosis Patients
Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit
To assess the efficacy of an intravenous nonnarcotic pain medication on controlling patient pain. To assess the effect of an intravenous nonnarcotic pain medication on patient sedation levels in neurocritically ill patients.
- Conditions
- Post-operative Craniotomy Patients, Carotid Endarterectomy and Carotid Artery Stenosis Patients, Post-op Spine Patients Admitted to the NCCU, Endovascular Patients Undergoing Intracranial Intervention
- Trial name
- NCT01948505
- Testing
- Intravenous acetaminophen
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Utah
Coronary Artery Disease, Coronary Restenosis
SCRIPPS V: Intracoronary Brachytherapy for Recurrent Restenosis After Multiple Drug-Eluting Stents
This study is a prospective study of patients treated at Scripps Clinic with intracoronary brachytherapy for recurrent restenosis within drug eluting stents.
- Trial name
- NCT00714545
- Testing
- Intracoronary brachytherapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Scripps Health
Coronary Artery Disease
ABSORB II Randomized Controlled Trial
Prospective, randomized (2:1), active control, single blinded, parallel two-arm, multi-center clinical investigation using Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System (ABSORB BVS); compared to…
- Trial name
- ABSORB II (NCT01425281)
- Testing
- Abbott Vascular XIENCE Everolimus Eluting Coronary Stent System, Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System
- Where
- Belgium
- Volunteers
- 501 people
- Sponsor
- Abbott Medical Devices
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