Clinical trials: Artery Stenosis
Stroke, Ischemic Attack, Transient
Carotid Plaque Imaging in Acute Stroke
The purpose of this study is to determine the frequency, characteristics, and consequences of vulnerable carotid artery plaques ipsilateral to an acute ischemic stroke or TIA in the territory of the internal carotid artery.
- Trial name
- CAPIAS (NCT01284933)
- Where
- 4 sites in Germany
- Volunteers
- 234 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Transcatheter Aortic Valve Replacement, Coronary Artery Disease
Coronary Artery Disease Assessment Strategies in TAVI Patients
Coronary artery disease (CAD) and aortic stenosis frequently coincide. Before valve intervention, invasive coronary angiography is routinely performed to assess coronary status.
- Conditions
- Transcatheter Aortic Valve Replacement, Coronary Artery Disease, Heart Disease Risk Factors
- Trial name
- CAT (NCT06559332)
- Testing
- Risk-based CAD management, Invasive coronary angiography
- Where
- Switzerland
- Volunteers
- 546 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Stenosis, Carotid Stenosis
Detection of Coronary Stenosis With Intravenous Microbubbles
To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.
- Conditions
- Coronary Stenosis, Carotid Stenosis, Myocardial Reperfusion
- Trial name
- NCT00580580
- Testing
- Optison, Definity, PESDA
- Sponsor
- University of Nebraska
Renal Transplant
Efficacy and Safety Study of Aspirin for the Prevention of Renal Artery Stenosis in Renal Transplantation Recipients
The anastomotic and peripheral stenosis of the transplanted kidney artery is one of the most important causes of graft failure in renal transplantation.
- Trial name
- NCT04260828
- Testing
- Aspirin 100mg
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Henan Provincial People's Hospital
Intracranial Arteriosclerosis, Ischemic Preconditioning
Remote Ischemic Conditioning Combined With Endovascular Stenting for Symptomatic Intracranial Atherosclerotic Stenosis
The purpose of this registry is to evaluate the safety and efficacy of RIC for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) undergoing endovascular therapy.
- Conditions
- Intracranial Arteriosclerosis, Ischemic Preconditioning, Endovascular Procedures
- Trial name
- NCT05653505
- Testing
- Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Huanhu Hospital
Erectile Dysfunction
Pudendal Assessment in Erectile Dysfunction
The study will address the role of internal pudendal artery disease in erectile dysfunction (ED), and whether it might eventually be amenable to intervention with stenting.
- Trial name
- INDEED (NCT01262833)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Coronary Atherosclerosis, Myocardial Infarction
CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow
The CANARY (Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow) Study is a pivotal trial to evaluate criteria for defining a Lipid Core Plaque (LCP) that is at high risk of rupturing during standard of…
- Conditions
- Coronary Atherosclerosis, Myocardial Infarction, Coronary Plaque Embolization
- Trial name
- CANARY (NCT01268319)
- Testing
- Embolic Protection Device (EPD), Intracoronary Spectroscopy and Ultrasonic Evaluation, Angioplasty and Stent Implant
- Where
- 9 sites in United States
- Volunteers
- 85 people
- Sponsor
- Infraredx
Atherosclerotic Renal Artery Stenosis, Fractional Flow Reserve
FFR-Guided Revascularization in Atherosclerotic Renal Artery Stenosis
For patients with atherosclerotic renal artery stenosis, the results of randomized controlled trials published in recent years have failed to demonstrate that renal artery stenting is superior to optimal medical therapy.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Fractional Flow Reserve, Optimal Medical Therapy, Stent Implantation
- Trial name
- FARS (NCT07511309)
- Testing
- Randomized to stenting, stent implantation, Randomized to optimal medical therapy (OMT)
- Where
- 20 sites in China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Ischemic Heart Disease, Coronary Artery Stenosis
A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions
This is a prospective, single-arm, open-label, multi-center, observational study to assess the acute safety and efficacy of MINI TREK RX 1.20 mm for enlarging coronary luminal diameter during percutaneous coronary intervention…
- Conditions
- Ischemic Heart Disease, Coronary Artery Stenosis, Chronic Coronary Total Occlusion, Coronary Bypass Graft Stenosis
- Trial name
- CROSS (NCT01186198)
- Testing
- MINI TREK RX 1.20 mm Coronary Dilatation Catheter
- Where
- 4 sites in United States
- Volunteers
- 71 people
- Sponsor
- Abbott Medical Devices
Common Femoral Artery Stenosis, Calcification; Heart
Shockwave™ vs Surgical Endarterectomy for Calcified Severe Common Femoral Artery Stenosis: Comparison of Efficacy, Safety and Long-Term Outcomes
The investigators hypothesize that Shockwave with DCB is non-inferior to surgical endarterectomy for common femoral artery (CFA) stenosis with regard to primary efficacy and safety endpoints.
- Trial name
- Shockify (NCT06829914)
- Testing
- Shockwave Catheter, CFA Endarterectomy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor Research Institute
Aortic Valve Stenosis, Ventricular Outflow Obstruction, Left
Polish Registry of Common Carotid Artery Access for TAVI
Transcatheter aortic valve implantation (TAVI) is valuable treatment option for patients, who are at the high risk of surgical aortic valve replacement (AVR).
- Trial name
- POL-CAROTID (NCT03361007)
- Testing
- Transcatheter Aortic Valve Implantation (TAVI)
- Where
- 6 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Peripheral Arterial Disease, Stenosis
A Trail of Sperstent® Used for Residual Lesions of Femoropopliteal Arteries
This is a prospective, multi-center, randomized trial designed to investigate the efficacy and safety of Sperstent® peripheral spot stent system versus Everflex® self-expanding peripheral stent system in the endovascular…
- Conditions
- Peripheral Arterial Disease, Stenosis, Dissection
- Trial name
- SURF (NCT06539689)
- Testing
- Sperstent® peripheral spot stent system, Everflex® self-expanding peripheral stent system
- Where
- 12 sites in China
- Volunteers
- 240 people
- Sponsor
- FrontAce Scientific Co., Ltd
Coronary Heart Disease
Analysis of Coronary CT Angiography to Identify Patients With Significant Coronary Artery Stenosis
The investigators propose to develop a computational framework involving a novel automatic image segmentation algorithm based on CTA images, an artery model reconstruction algorithm for stenosis detection, and quantification of…
- Trial name
- CTAAnalyzer (NCT02791113)
- Testing
- Fractional Flow Reserve (FFR) Measurement
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National Heart Centre Singapore
Carotid Artery Stenosis
A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection
The primary objective of this study is to evaluate carotid artery stenting (CAS) with and without cerebral protection (CP) to determine if CP improves safety and effectiveness of CAS.
- Trial name
- NCT00177346
- Testing
- CAS with cerebral protection, CAS without cerebral protection
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pittsburgh
Cognitive Manifestations
Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates
Carotid artery plaques are known to cause stroke. Cognitive impairment is an insidious but poorly understood problem in patients with carotid plaques.
- Trial name
- ACCOF (NCT01353196)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Carotid Stenosis
Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis
Atherosclerotic carotid artery stenosis is a major cause of stroke, and early identification of high-risk patients combined with surgical intervention can significantly reduce stroke risk.
- Trial name
- NCT06452173
- Testing
- Plasma, carotid high-resolution magnetic resonance imaging
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tiantan Hospital
Systematic Intracranial Artery Stenosis
Stenting for Symptomatic Intracranial Artery Stenosis Registry in China
Stenting for systematic Intracranial artery stenosis is challenged recently, especially for safety. This registry is aimed to explore the safety profile during peri-operation period in Stenting procedures for systematic…
- Trial name
- NCT01830413
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital
Coronary Artery Stenosis
Observational Study to Evaluate Short and Long-term Safety of the ABSORB Scaffold
The German-Austrian ABSORB Register shall provide an analysis of acute and long-term safety as well as therapy outcomes of the ABSORB (trade mark) bioresorbable vascular scaffold system in patients suffering from coronary artery…
- Trial name
- GABI-R (NCT02066623)
- Testing
- ABSORB Scaffold
- Where
- 81 sites in Austria, Germany
- Volunteers
- 3,330 people
- Sponsor
- IHF GmbH - Institut für Herzinfarktforschung
Unruptured Intracranial Aneurysm, Arteriovenous Cerebral Malformations
ACtive Catheterization for EndovaScular TreatmentS
The objective of this clinical investigation is to evaluate the safety and technical success of the Basecamp Vascular controllable directional GECKO guidewire when used to facilitate endovascular access to the targeted vessel in…
- Conditions
- Unruptured Intracranial Aneurysm, Arteriovenous Cerebral Malformations, Carotid Stenosis
- Trial name
- ACCESS (NCT05355259)
- Testing
- GECKO Active Guidewire
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Basecamp Vascular
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