Clinical trials: Arthritis, Degenerative
Degenerative Osteoarthritis, Post-traumatic; Arthrosis
Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft
The purpose of this clinical trial is to evaluate the outcome of implanting AlloStem® graft with appropriate rigid internal fixation hardware as an alternative to autograft bone graft with rigid fixation in subtalar arthrodesis…
- Conditions
- Degenerative Osteoarthritis, Post-traumatic; Arthrosis, Rheumatoid Arthritis & Other Inflammatory Polyarthropathies, Rheumatoid Arthritis of Subtalar Joint
- Trial name
- NCT01413061
- Testing
- Subtalar Arthrodesis
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- AlloSource
Osteoarthritis, Hip, Arthritis, Degenerative
A Retro-prospective Study of Total Hip Arthroplasty With EMPERION Modular Primary Stem in Australian Centres (HISTORIC)
This is a retro-prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in at least 156 subjects, at up to 10 sites in Australia, who have been implanted with the EMPERION™ Modular…
- Trial name
- HISTORIC (NCT02435420)
- Testing
- EMPERION Modular Primary Stem
- Where
- 8 sites in Australia
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Degenerative Arthritis
Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis
The purpose of this study is to determine whether TissueGene-C, an allogeneic human chondrocytes expressing Transforming Growth Factor(TGF)-b1, is effective and safe in patients with degenerative arthritis.
- Trial name
- NCT02072070
- Testing
- TissueGene-C
- Where
- 12 sites in South Korea
- Volunteers
- 163 people
- Sponsor
- Kolon Life Science
Arthritis, Degenerative, Arthritis, Rheumatoid
Excia T Cementless EBRA Study
In this Post Market Clinical Follow-up Study (PMCF Study), the short-term clinical and radiological results of the cementless Excia T® prosthesis in routine clinical use shall be assessed and the migration taking place in the…
- Conditions
- Arthritis, Degenerative, Arthritis, Rheumatoid, Hip Fractures, Femur Head Necrosis
- Trial name
- NCT02799654
- Where
- Germany
- Sponsor
- Aesculap AG
Osteoarthritis, Degenerative Arthritis
Journey II BCS CMS Total Knee System Compared to Other PS Total Knee Systems in PT Setting
The primary objective of the study is to determine how the short-term outcome of subjects implanted with the JOURNEY™ II BCS Total Knee System compares to subjects implanted with other PS total knee systems, and to determine if…
- Conditions
- Osteoarthritis, Degenerative Arthritis, Traumatic Arthritis
- Trial name
- NCT02820766
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Smith & Nephew, Inc.
Degenerative Arthritis, Osteoarthritis
I-beam and Cruciate Tibial Components Used in Total Knee Replacement
The purpose of this study is to compare the clinical outcomes of using an I-beam or cruciate tibial component in total knee replacement.
- Conditions
- Degenerative Arthritis, Osteoarthritis, Rheumatoid Arthritis, Knee Arthritis
- Trial name
- NCT00588783
- Testing
- I-beam design, Cruciate design
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Biomet Orthopedics, LLC
Degenerative Arthritis, Osteoarthritis
Total Knee Replacement With Duracon® and Vanguard™ Prostheses
The purpose of this study is to compare range of motion, Knee Society Scores, and duration of surgery for different total knee prostheses.
- Conditions
- Degenerative Arthritis, Osteoarthritis, Rheumatoid Arthritis, Knee Arthritis
- Trial name
- NCT00588887
- Testing
- Duracon®, Vanguard™
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthritis, Degenerative Arthritis
Vanguard Knee Anterior Stabilized Versus Posterior Stabilized Bearing Study
The purpose of this study is to compare the performance of two FDA-cleared tibial bearings (replacement for cartilage in the knee) by collecting data on patients through 3 years of follow-up.
- Trial name
- VGASPS (NCT01308515)
- Testing
- Vanguard Knee System with AS Bearing, Vanguard Knee System with PS Bearing
- Sponsor
- Zimmer Biomet
Arthrodesis, Degenerative Arthritis
INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
The primary objective of this study is to evaluate the radiographic outcomes of Total Ankle Arthroplasty in patients having a calcaneal stem.
- Conditions
- Arthrodesis, Degenerative Arthritis, Rheumatoid Arthritis, Complications; Arthroplasty, Mechanical
- Trial name
- NCT01366989
- Testing
- Radiographic evaluation of previously implanted patients
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stryker Trauma and Extremities
Degenerative Arthritis
Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis
The purpose of this study is to determine whether TissueGene-C, an allogeneic human chondrocytes expressing Transforming Growth Factor(TGF)-b1, is effective and safe in patients with degenerative arthritis
- Trial name
- NCT01671072
- Testing
- TissueGene-C, Normal Saline
- Where
- 3 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Kolon Life Science
Degenerative Arthritis
Efficacy and Safety Study of TissueGene-C Mixed With Fibrin-glue for the Patients With Degenerative Arthritis
The purpose of this study is to determine whether TissueGene-C, allogeneic human chondrocytes expressing Transforming Growth Factor(TGF)-b1, mixed with fibrin-glue is effective and safe in patients with degenerative arthritis.
- Trial name
- NCT01825811
- Testing
- TissueGene-C (Low dose), TissueGene-C (High dose)
- Where
- 6 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Kolon Life Science
Degenerative Arthritis
Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis
To assess the efficacy and safety of the intra-articular injection of TissueGene-C in patients with degenerative arthritis of the knee
- Trial name
- NCT02341378
- Testing
- TissueGene-C(Low dose), TissueGene-C(High dose)
- Where
- 3 sites in South Korea
- Volunteers
- 28 people
- Sponsor
- Kolon Life Science
Degenerative Joint Disease
Post-Market Study of the ICONACY Hip System
The purpose of this study is to evaluate the use and efficacy of the Iconacy Hip System for total hip replacement surgery.
- Trial name
- NCT02027974
- Testing
- Iconacy Hip System, Stryker Accolade Hip System
- Sponsor
- Iconacy Orthopedic Implants, LLC.
Degenerative Joint Disease
Multi-Site, Post-Market Study of the ICONACY I-Hip System
The purpose of this study is to evaluate the use and efficacy of the I-Hip for primary total hip replacement surgery.
- Trial name
- NCT02131389
- Testing
- Iconacy Hip System
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Iconacy Orthopedic Implants, LLC.
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
CoMplete™ Acetabular Hip System
The primary objective of this investigation is to evaluate survivorship at ten years. For this post approval study (PAS), a maximum acceptable hazard of revision is assumed to be a constant 1% per year.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Post-traumatic Arthritis
- Trial name
- NCT01543230
- Testing
- Total hip replacement
- Where
- 6 sites in United States
- Volunteers
- 58 people
- Sponsor
- DePuy Orthopaedics
Degenerative Arthritis, Inflammation
The Effects of Elmore Oil on Patients With Osteoarthritis
The treatment of osteoarthritis, a disease that eventually affects the majority of the older population, involves the alleviation of symptoms such as pain and stiffness, and the reduction of inflammation.
- Trial name
- NCT01684371
- Testing
- Two oily solutions (Blue Dotted and Orange Dotted Elmore Oils)
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- Elmore Oil Company Pty Ltd