Clinical trials: Arthritis, Rheumatoid (RA)
Rheumatoid Arthritis
Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment
This nationwide, multicenter, single arm, prospective, non-interventional study will evaluate the quantitative pattern of NSAID use and the impact of treatment with tocilizumab on NSAID use in a representative cohort of…
- Trial name
- CONIFER (NCT03112213)
- Testing
- Tocilizumab, NSAIDs
- Where
- 27 sites in Germany
- Volunteers
- 135 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
A Study to Assess Efficacy With Respect to Clinical Improvement in Disease Activity and Safety of Tocilizumab in Patients Wtih Active Rheumatoid Arthritis.
This single arm study will assess the effectiveness of tocilizumab in combination with traditional DMARDs with regard to the clinical improvement in disease activity (achievement of LDAS) after 24 weeks' treatment in patients…
- Trial name
- NCT00754559
- Testing
- Tocilizumab
- Where
- 81 sites in Germany
- Volunteers
- 286 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
A Non-Interventional Study in Rheumatoid Arthritis Patients Treated With Tocilizumab (RoActemra/Actemra)
This multi-center, non-interventional study will evaluate the pattern of usage in clinical practice, efficacy and safety of tocilizumab in patients with rheumatoid arthritis.
- Trial name
- NCT01613378
- Testing
- No intervention
- Where
- 32 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Hoffmann-La Roche
Arthritis, Rheumatoid
Open Label, Dose-Regimen Study Evaluating Etanercept 50 mg Once-Weekly In Japanese Subjects With RA
The primary purpose of this study is to evaluate the safety and efficacy of a once-weekly dose of etanercept for rheumatoid arthritis. Currently, patients in Japan can only use 25 mg etanercept two times a week.
- Trial name
- NCT00418717
- Testing
- etanercept
- Where
- 12 sites in Japan
- Volunteers
- 42 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Rheumatoid Arthritis
Observational Real-world Evaluation of Cost of Infections of Rheumatoid Arthritis (RA) Patients on Biologics
To quantify the incremental cost of infections in patients treated with etanercept, adalimumab or infliximab versus abatacept.
- Trial name
- NCT01166620
- Volunteers
- 4,000 people
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis
Long-term Observational Study to Evaluation the Safety of FURESTEM-RA Inj
Observational Study to evaluate the safety of FURESTEM-RA lnj. in moderate to severe rheumatoid arthritis patients who participated in phase 1 clinical trial of FURESTEM-RA lnj.
- Trial name
- NCT03106259
- Testing
- FURESTEM-RA Inj.
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Rheumatoid Arthritis (RA)
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function.
- Trial name
- NCT04888585
- Testing
- ABBV-154
- Where
- 220 sites in United States, Australia and 19 more
- Volunteers
- 473 people
- Sponsor
- AbbVie
Rheumatoid Arthritis
Multiple Doses Escalation Study of SHR0302 in Rheumatoid Arthritis (RA) Patients
Condition: Rheumatoid Arthritis Intervention: Drug: SHR0302; Drug: SHR0302 placebo comparator Phase: Phase 1 Study Type: Interventional Study Design: Treatment, Parallel Assignment, Double Blind (Subject, Caregiver, Investigator…
- Trial name
- NCT02665910
- Testing
- SHR0302
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Rheumatoid Arthritis (RA)
Phase I Study to Evaluate Safety, Tolerability, Pharmacokinetic, and Food Effects of ARD-885 Film-coated Tablets in Healthy Chinese Subjects and Patients With Rheumatoid Arthritis
The proposed study is a randomized, double-blind, placebo-controlled single and multiple ascending dose phase I study to evaluate the safety, tolerability, pharmacokinetic, and food effects of ARD-885 Film-coated Tablets in…
- Trial name
- NCT07266207
- Testing
- ARD-885 Tablets
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Artivila (Shenzhen) Innovation Center, Ltd
Rheumatoid Arthritis (RA)
An Open-label Study of Cizutamig in Refractory Seropositive Rheumatoid Arthritis
The purpose of the study is to evaluate the safety and efficacy of BCMAxCD3 T-cell engager (cizutamig) in patients with refractory seropositive RA.
- Trial name
- NCT06946199
- Testing
- Cizutamig
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lyme Borreliosis, Fibromyalgia
Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain
Chronic pain is a major symptom shared by several medical conditions. This study focuses on five well-defined chronic diseases : Lyme Borreliosis (LB), Post-Acute COVID-19 Syndrome (PACS or "long COVID"), fibromyalgia…
- Conditions
- Lyme Borreliosis, Fibromyalgia, Rheumatoid Arthritis (RA), Post Acute COVID 19 Syndrome
- Trial name
- NCT07871578
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Central Hospital, Nancy, France
Rheumatoid Arthritis
Phase 1b Study of PLX5622 in Rheumatoid Arthritis Patients Who Are Receiving Methotrexate
PLX115-02 is a phase 1b study to assess how the study drug, PLX5622: 1. affects the body, 2. how the body affects PLX5622 3. the interaction of PLX5622 with Methotrexate and 4.
- Trial name
- NCT01329991
- Testing
- PLX5622
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- Plexxikon
Arthritis, Rheumatoid
Treat-to-target in RA: Collaboration To Improve adOption and adhereNce
The purpose of this study is to determine if a Learning Collaborative is an effective tool to improve adoption and adherence to a Treat-to-Target (TTT) treatment strategy in U.S.
- Trial name
- TRACTION (NCT02260778)
- Testing
- Learning Collaborative
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rheumatoid Arthritis, Diabetic Neuropathy
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
- Trial name
- NCT05573685
- Testing
- DiNaMo Study App
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Click Therapeutics, Inc.
Rheumatic Disorder, Rheumatoid Arthritis (RA)
DETECTRA: Remote Monitoring to Detect Rheumatoid Arthritis Flares and Treatment Response
The goal of this clinical trial is to learn if the DETECTRA remote monitoring platform can help clinicians detect rheumatoid arthritis (RA) disease flares earlier and more reliably, as well as identify response and non-response…
- Trial name
- Pix-Monitor (NCT07857993)
- Testing
- DETECTRA, Standard of Care (SOC)
- Where
- 3 sites in Austria, Germany
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Rheumatoid Arthritis
ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)
This study evaluates ATI-450 plus MTX versus placebo plus MTX in participants with moderate to severe active RA who have had an inadequate response to MTX alone.
- Trial name
- NCT05279417
- Testing
- ATI-450 50 mg oral tablet BID, Methotrexate, ATI-450 20 mg oral tablet BID
- Where
- 50 sites in United States, Bulgaria and 2 more
- Volunteers
- 251 people
- Sponsor
- Aclaris Therapeutics, Inc.
Telitacicept, Treatment Compliance
Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis
The aim of this study is to observe the clinical efficacy and safety of telitacicept combined with baricitinib in the treatment of D2TRA patients
- Conditions
- Telitacicept, Treatment Compliance, Rheumatoid Arthritis
- Trial name
- NCT07491016
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang Provincial People's Hospital
Rheumatoid Arthritis, Rheumatoid Arthritis (RA
Development and Evaluation of the Effectiveness of the SMART-HAND Protocol for Hand Rehabilitation in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) frequently affects the hand and wrist, resulting in pain, reduced joint stability, impaired proprioception, muscle weakness, and limitations in daily activities.
- Conditions
- Rheumatoid Arthritis, Rheumatoid Arthritis (RA, Rheumatoid Arthritis (RA) Prevention
- Trial name
- NCT07754552
- Testing
- SMART-HAND Protocol, Conventional Hand Rehabilitation, Joint Protection and Ergonomic Education
- Volunteers
- 132 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Pain, Stress
KickStart30: A 30-Day Intervention for Patients With Rheumatoid Arthritis (RA)
This study explores the efficacy and feasibility of a self-management wellness intervention that is integrated, prescriptive, and trackable in a population of patients with Rheumatoid Arthritis (RA) taking a biologic.
- Conditions
- Chronic Pain, Stress, Psychological, Healthy
- Trial name
- KickStart30 (NCT03993548)
- Testing
- Wellness Element 1 - Exercise, Wellness Element 2 - Mindfulness, Wellness Element 3 - Sleep Hygiene
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
RA & OP Relationship
The Relationship Between Rheumatoid Arthritis and Osteoporosis and Factors Contributing to This Connection
This study aims to explore the association between RA and osteoporosis and highlight the risk factors that RA patients have that may cause or affect osteoporosis progress.
- Trial name
- NCT06038292
- Testing
- DXA Scan
- Volunteers
- 105 people
- Sponsor
- Assiut University