Clinical trials: Arthritis, Unspecified
Thumb Osteoarthritis
Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis
Osteoarthritis of trapezio-metacarpal joint (TMJ) most commonly occurs in women over 50 years old, often bilateral and it is a disabling condition presenting with pain at base of the thumb, swelling, instability, deformity and…
- Trial name
- NCT07171840
- Testing
- 10 cc of oxygen-ozone plus thumb splint, thumb splint
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Humanitas Clinical and Research Center
Osteoarthritis, Knee
Experimental Study of Strength Training to Activate the Quadriceps Muscle After Total Knee Arthroplasty
Background: Progressive strength training is a training modality used in rehabilitation after total knee arthroplasty (TKA). Strength deficits up to 80% in the quadriceps muscle is shown to be present in the operated leg after…
- Trial name
- NCT01713140
- Testing
- 1 strength training set performed until contraction failure
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Gonarthrosis, Arthroplasty
Rehabilitation with Personalized Strategies According to Muscle Volume Before Knee Arthroplasty
Preoperative rehabilitation before total knee arthroplasty (TKA) has not been proven to be effective. Latest meta-analyzes do not find any improvement of motor performance during gait 6 months after surgery.
- Trial name
- REPERAGE (NCT04318197)
- Testing
- Personalized rehabilitation program with electrostimulation, Global rehabilitation program
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Rheumatoid Arthritis
Rheumatoid Foot Insole
The present study aims to evaluate the effect of insoles for foot arthritis.
- Trial name
- NCT01546610
- Testing
- insoles intervention
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Rheumatoid Arthritis
A Non-Interventional Study of RAYOS in Adult Patients With Rheumatoid Arthritis
The overall objective of the study is to assess the effectiveness of switching from immediate-release prednisone (conventional) therapy to delayed-release prednisone (RAYOS) in patients with moderately to severely active…
- Trial name
- SUNRAY (NCT02287610)
- Testing
- RAYOS (delayed-release prednisone)
- Volunteers
- 75 people
- Sponsor
- Amgen
Osteoarthritis of the Knee
Study of Safety and Efficacy of Diractin® for the Treatment of Osteoarthritis (OA) of the Knee
The purpose of this study is to provide replicated evidence of safety and efficacy of 100 mg ketoprofen in Diractin®.
- Trial name
- NCT00722852
- Testing
- ketoprofen in Diractin®
- Where
- 37 sites in United States
- Volunteers
- 555 people
- Sponsor
- IDEA AG
Osteoarthritis of the Knee
Evaluation of Amniotic Fluid Product in Knee Osteoarthritis
A study evaluating Amniotic Fluid compared to a Saline Placebo Injection in the treatment of subjects with osteoarthritic (OA) knee pain
- Trial name
- NCT02768155
- Testing
- Amniotic Fluid 4.0ml dose, Amniotic Fluid 2.0ml dose
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- MiMedx Group, Inc.
Arthritis, Ultrasonication
The Efficacy of Ultrasonication in Combination With Corticosteroid Intraarticular Injection for Arthritis
This study investigates whether ultrasound therapy applied prior to intra-articular corticosteroid injection can enhance the treatment efficacy for patients with joint arthritis and assess its safety.
- Conditions
- Arthritis, Ultrasonication, Intra-articular Injections, Rheumatology
- Trial name
- NCT07363876
- Testing
- Therapeutic Ultrasound, Intra-articular corticosteroid injection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taichung Veterans General Hospital
Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease
PMCF Study on the Safety, Performance and Clinical Benefits Data of the NexGen TM Augmentation Patella
The study is a single-center, retrospective and prospective, non-randomized, non-controlled and consecutive series post-market study.
- Conditions
- Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease, Functional Deformity, Revision Total Knee Arthroplasty
- Trial name
- NCT05253976
- Where
- Switzerland
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Comparison of Effectiveness of Two Different Electrotherapy Agents on Central Sensitization
The aim of this study is to compare the efficacy of transcutaneous electrical nerve stimulation (TENS), interferential currents (IFCs) and sham devices in improving central sensitization (CS) findings, including pressure pain…
- Trial name
- NCT04153825
- Testing
- Transcutaneous Electrical Nerve Stimulation, Interferential Current, Hydrocollator hot-pack
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Turkish League Against Rheumatism
Shoulder Pain, Shoulder Injuries
SPR PNS for Chronic Shoulder Pain
The purpose of this research is to gather post-market data regarding the effectiveness of the SPRINT Peripheral Nerve Stimulation (PNS) System for the treatment of chronic shoulder pain due to chronic degenerative changes of your…
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT05649917
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- International Spine, Pain and Performance Center
Rheumatoid Arthritis
A Study of Rheumatoid Arthritis Patients on Adalimumab to Evaluate Quality of Life Variables, Effects on Work Productivity and Functional Outcomes in Malaysia
An observational, non-interventional study on social, economic and quality-of-life outcomes of Adalimumab use in participants with moderate to severe active Rheumatoid Arthritis.
- Trial name
- RELIVE (NCT01387789)
- Where
- 13 sites in Malaysia
- Volunteers
- 71 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Osteoarthritis
Total Knee Arthroplasty Comparing Cementless to Cemented Fixation
The purpose of this study is to determine if there are any clinical or radiographic differences in cemented and cementless fixation in total knee replacement.
- Trial name
- NCT01335438
- Testing
- Cementless (Nexgen), Cemented (Nexgen)
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Young Hoo Kim
Osteoarthritis
Bone Mineral Density (BMD) in Cemented Versus Cementless Hip Resurfacing
The purpose of this study is to compare the bone mineral density of patients who have undergone either cemented or cementless hip resurfacing.
- Trial name
- NCT01353326
- Testing
- Cormet, Conserve
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis (Knee OA)
Comparison of SVF Injection With and Without Microfracture in Moderate Knee Osteoarthritis
This prospective, randomized controlled clinical trial aims to evaluate the clinical and radiological effects of combining stromal vascular fraction (SVF) therapy with arthroscopic microfracture in patients with knee…
- Trial name
- NCT07112885
- Testing
- Arthroscopic Microfracture Combined with Autologous SVF Injection, Arthroscopic Debridement Followed by Autologous SVF Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Osteo Arthritis of the Knee
Lubricin-inspired Osteoarthritis Treatment: a Unique Solution
This goal of this open label study is to evaluate the safety and tolerability of a single intra-articular administration of ABR1 in adults with knee osteoarthritis with a KL grade from 2 to 4.
- Trial name
- LOTUS (NCT07611708)
- Testing
- ABR1
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- Pleryon Therapeutics (Hangzhou) Limited
Rheumatoid Arthritis
TORPEDO Study: A Study on Rapid Effect of Tocilizumab in Patients With Rheumatoid Arthritis With an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) or Anti-TNF
This study will assess the onset and maintenance of effect of tocilizumab on relief in patients with active moderate or severe rheumatoid arthritis who have had an inadequate response to DMARDs or anti-TNF.
- Trial name
- NCT00977106
- Testing
- tocilizumab [RoActemra/Actemra]
- Where
- 22 sites in France
- Volunteers
- 103 people
- Sponsor
- Hoffmann-La Roche
Knee Osteoarthritis
Clinial Application of Park et al.(The Knee 27 (2020) 1577-1584)'s Study
The goal of this study was to perform pulsed radiofrequency ablation with a modified target suggested in the cadaver study by Park et al.
- Trial name
- NCT05202847
- Testing
- pulsed radiofrequency ablation to modifined points group, pulsed radiofrequency ablation to conventional points group
- Sponsor
- Gangnam Severance Hospital
Pharmacokinetics, Safety Issues
A Clinical Study With Adalimumab Biosimilar
The study aims to evaluate the pharmacokinetic profile, safety profile, and immunogenic potential of adalimumab of a new citrate-free formulation of adalimumab (Adalimumab Richmond) [Test Product] vs.
- Trial name
- NCT06291948
- Testing
- Humira® (adalimumab) AC Pen [Reference Product], Adalimumab Richmond [Test Product]
- Where
- Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laboratorios Richmond S.A.C.I.F.
Osteoarthritis
Hydroxyethyl Starch and Renal Function After Hip Replacement Surgery
The purpose of this project is to investigate if hydroxyethyl starch (HES) is potential nephrotoxic and examine the effects on the circulation and kidneys during administration of HES during surgery.
- Trial name
- VOHO (NCT01486576)
- Testing
- Voluven (Hydroxyethyl starch 130/0,4), Sodium Chloride 9 mg/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Regional Hospital Holstebro
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