Clinical trials: Arthritis
Subtalar Arthritis, Subtalar Instability
Dynamic Imaging of the Subtalar Instability
The purpose of this study is to describe normal dynamic computed tomography anatomy of hind foot in inversion/eversion movement, and to define diagnostic criteria for subtalar instability.
- Trial name
- IDIS (NCT02887131)
- Testing
- Dynamic CT of the ankle
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
Brain Diseases, Central Nervous System Diseases
Digital Diagnostics and Intervention Services for Parkinson's Disease
People with Parkinson's have infrequent clinical consultation (once every 12-18 months) and limited rehabilitation. Assessment play an important role in these consultations to help clinicians understand patients' health status…
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Joint Diseases
- Trial name
- NCT06534177
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Rheumatoid Arthritis, Coronary Artery Disease
Effects of Interleukin-1 Inhibition on Vascular and Left Ventricular Function in Rheumatoid Arthritis Patients With Coronary Artery Disease
Inhibition of interleukin-1 (IL-1) activity in patients with RA without CAD ameliorates vascular and LV function. Moreover, data from species shows beneficial effect of this treatment on LV function after experimental myocardial…
- Conditions
- Rheumatoid Arthritis, Coronary Artery Disease, Inflammation
- Trial name
- NCT01566201
- Testing
- anakinra
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Athens
Hip Osteoarthritis
Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty
Monitor the performance of the Mpact cup in the treatment of patients with hip joint disease requiring a total hip replacement.
- Trial name
- NCT03897595
- Testing
- MPact Cup
- Where
- 5 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Rheumatoid Arthritis
Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects synovial joints, leading to pain, swelling, and progressive joint damage. Early diagnosis is critical to prevent irreversible disability.
- Trial name
- Anti-pcolce/RA (NCT07129837)
- Testing
- Clinical evaluation, disease activity and disability scoring, and laboratory testing including RF, anti-CCP, and serum anti-PCOLCE antibody measurement by ELISA.
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis of Knee, Central Sensitization
Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty
Analgesic effect of 20mg Duloxetine was evaluated at regular short term intervals in patients without central sensitivity and undergoing bilateral single sitting total knee arthroplasty for tricompartmental osteoarthritis using…
- Conditions
- Osteoarthritis of Knee, Central Sensitization, Central Sensitisation
- Trial name
- NCT06837012
- Testing
- Duloxetine - low dose
- Where
- India
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Arthroscopy Knee and Shoulder Clinic
Surgery, Hip Osteoarthritis
Two Year Study With Robotic-Arm Assisted Hip Surgery.
This study will involve a quantitative assessment of prospectively collected computed tomography, radiographic and patient outcomes data from multiple centers.
- Trial name
- NCT03891199
- Testing
- Robotic-Arm Assisted THA
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Rheumatoid Arthritis, Leukocytes, Mononuclear
Genetics and Mechanisms of Rheumatoid Arthritis
The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia.
- Conditions
- Rheumatoid Arthritis, Leukocytes, Mononuclear, Genetic Association Studies
- Trial name
- RASGENAS (NCT01788098)
- Where
- Slovakia
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Rheumatoid Arthritis
Evaluation of SC Injected Tc 99m Tilmanocept Localization in Active RA Subjects by SPECT and SPECT/CT Imaging
Determine the localization of Tc 99m tilmanocept by SPECT and SPECT/CT imaging in subjects with active RA and concordance with clinical symptomology.
- Trial name
- NCT02683421
- Testing
- Tilmanocept
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Navidea Biopharmaceuticals
Osteoarthritis, Knee
A Study of the Construct Validity of Community Walking Speed Data Collected Remotely With the Canary canturioTM te Tibial Extension
The purpose of this study is to determine the construct validity of the Canary Tibial Extension's measure of self-selected community walking speed.
- Trial name
- NCT05539326
- Testing
- Performance Clinical Outcome Test
- Where
- 6 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Canary Medical
Knee Arthroplasty
The Efficiency of the PNF Method
Background: Early rehabilitation following knee arthroplasty is an integral part of medical management which reduces the time of patient's stay at hospital and eliminates the risk of post-operative complications.
- Trial name
- NCT04686071
- Testing
- PNF method, Standard rehabilitation
- Where
- 2 sites in Poland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Knee Osteoarthritis
Intra-articular Pulsed Radiofrequency Neuromodulation Versus Intra-articular Steroids for Painful Knee Osteoarthritis
To compare the efficacy of intra-articular pulsed radiofrequency to intra-articular steroids in patients with moderate-severe painful osteoarthritis of the knee.
- Trial name
- NCT04238598
- Testing
- Pulse Radiofrequency, Standard of Care Intra- Articular Injection
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Center For Interventional Pain and Spine
Ankylosing Spondylitis
SLAMF1 Gene Expression in Ankylosing Spondylitis
This cross-sectional study aims to evaluate SLAMF1 gene expression levels in patients with ankylosing spondylitis compared with healthy controls.
- Trial name
- NCT07907913
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gonarthrosis
Intraarticular Collagen in Patients With Gonarthrosis
The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age.
- Trial name
- NCT06275880
- Testing
- Intra-articular infiltration of PVP Collagen, Rehabilitation
- Where
- Mexico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Knee Osteoarthritis, Task Performance and Analysis
Knee Osteoarthritis, Motor Control, Risk of Falls and Virtual Reality
The goal of this clinical trial is to learn about knee osteoarthritis, functionality, and risk of falls in community-dwelling adults aged 60 years and older.
- Conditions
- Knee Osteoarthritis, Task Performance and Analysis, Accidental Falls, Virtual Reality
- Trial name
- NCT06362785
- Testing
- Virtual Reality, Therapeutic exercise
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Spondyloarthritis
A Study of Novel Immune Modulating Biomarkers in Patients With Spondyloarthritis With Axial Involvement
Spondyloarthritis refers to a set of inflammatory disorders that mainly afflict the spine, joints and ligaments. A subtype of spondyloarthritis is Ankylosing Spondylitis - now known as axial spondyloarthropathy - which is…
- Trial name
- NCT01969188
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Psoriasis, Psoriatic Arthritis
Genetic Variation in TRAF3IP2 (rs13190932)
Psoriasis is an immune-mediated inflammatory disease that is highly prevalent worldwide, affecting approximately 2-3% of the world population.
- Trial name
- NCT07086924
- Testing
- Methotrexate
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South Valley University
Sacroiliitis
Frequency of Sacroiliitis in Inflammatory Bowel Disease Patients Using MRI
1. to determine the overall frequency of Inflammatory sacroiliitis among patients with Inflammatory bowel disease using magnetic resonance imaging 2.
- Trial name
- NCT06034808
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sjogren's Syndrome
Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT
Sjögren's syndrome (SS) is a chronic autoimmune disease primarily affecting the salivary and lacrimal glands, leading to symptoms of dryness. Assessing the inflammatory activity is crucial for guiding treatment.
- Trial name
- NCT07062523
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
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