Clinical trials: Arthritis Foot
Hallux Rigidus
Surgical Treatment for Great Toe Arthritis
After potential subjects determine that they would like surgical treatment of their great toe arthritis, study staff will approach them about the study.
- Trial name
- NCT03935880
- Testing
- Cartiva Implant, Cheilectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Osteoarthritis of First Metatarsalphalangeal Joint
A Study to Evaluate the Effectiveness and Safety of an Implant in the Treatment of Osteoarthritis of the Great Toe
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the great toe.
- Trial name
- NCT00969969
- Testing
- Arthrodesis, Cartiva
- Where
- 12 sites in Canada, United Kingdom
- Volunteers
- 236 people
- Sponsor
- Cartiva, Inc.
Osteoarthritis Ankle, Osteoarthritis
SPECT-CT vs MRI for the Diagnosis of Osteoarthritis in the Foot and Ankle
The diagnose of symptomatic osteoarthritis in the ankle, mid- and hind foot remains challenging. There is no gold standard for the work-up and various hospitals use different protocols.
- Trial name
- NCT05912153
- Testing
- SPECT/CT, MRI
- Where
- Netherlands
- Volunteers
- 132 people
- Sponsor
- Martini Hospital Groningen
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Ankle Arthritis, Foot Arthritis
The Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis.
- Trial name
- NCT03686241
- Testing
- Tibiotalocalcaneal (TTC) arthrodesis, DynaNail
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MedShape, Inc
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Arthritis
Weight-Bearing Tomosynthesis In Evaluation of Foot/AnkIe
This study aims to compare digital tomosynthesis with radiography and weight-bearing CT as an imaging technique to assess arthritis in the foot and ankle.
- Trial name
- NCT02432170
- Testing
- Digital Tomosynthesis of Foot and Ankle
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Washington
Diabetic Foot, Osteoarthritis
PET/CT Scanning for the Follow-up of Antibiotic Treatment of Infectious Osteoarthritis in the Diabetic Foot
The investigators' primary objective is to assess the predictive power of PET/CT scanning in the evolution of infectious osteoarthritis of the diabetic diabetic after antibiotic therapy prescribed by national and international…
- Trial name
- ISEOD (NCT01322256)
- Testing
- Bone scintigraphy, Leukoscan, PET / CT
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Posterior Tibial Tendon Dysfunction, Pes Planus
Frequency of Pes Planus and Posterior Tibial Tendon Dysfunction in Patients With Ankylosing Spondylitis
This investigation aims to investigate the frequency of pes planus and posterior tibial tendon dysfunction in patients with ankylosing spondylitis.
- Conditions
- Posterior Tibial Tendon Dysfunction, Pes Planus, Spondylitis, Ankylosing
- Trial name
- NCT04810715
- Testing
- Patients with Ankylosing Spondylitis
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Afyonkarahisar Health Sciences University
Hallux Rigidus
Managing Pain in Patients With MTP Arthritis
Hallux rigidus is a degenerative disease of the first metatarsophalangeal (MTP) joint which affect 2.5% of people over the age of 50. As the arthritis progresses, patients pain levels increase and range of motion decreases.
- Trial name
- NCT04833608
- Testing
- Vktory insoles, Morton's extension insoles
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Arthritis Foot, Bone Alignment Defaults
Evaluation of the Treatment of Arthritis and the Correction of Bone Alignment Default of the Toes With Lync
The "LYNC" clinical investigation aims to confirm the clinical benefits, performance and safety of the Lync® device when implanted in the toes for the treatment of arthritis and correction of bone misalignments.
- Trial name
- LYNC (NCT06888934)
- Testing
- Intervention with Lync device.
- Where
- 5 sites in France
- Volunteers
- 76 people
- Sponsor
- Novastep
Knee Osteoarthritis (OA)
Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program in Patients With Knee Osteoarthritis.
Knee osteoarthritis (OA) is also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elder population.
- Trial name
- NCT06658249
- Testing
- Core Stabilization Exercises with Foot-Ankle Strengthening Program, Foot-Ankle Strengthening Program
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
Joint Ultrasound Evaluation of Asymptomatic Rheumatic Feet
Objectives: The aims of the present study were to compare ultrasound on asymptomatic feet of patients with rheumatoid arthritis (RA) and normal controls, determine the association between ultrasound and global disease activity…
- Trial name
- NCT01677416
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Osteoarthritis, Knee
Combination of Lateral Foot Orthoses and Knee Brace for Treatment of the Knee Osteoarthritis
The purpose of this study is to evaluate the immediate and short-term effects of the combination of lateral customized foot orthoses on the pain and medial knee loading during gait among medial knee osteoarthritis patients.
- Trial name
- NCT01870336
- Testing
- Combined treatment of medial knee osteoarthritis
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Laval University
Ankle Fractures, Post-traumatic Osteoarthritis
Custom Dynamic Orthoses to Reduce Articular Contact Stress
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle. Research suggests that ankle arthritis develops following ankle fracture due, in part, to elevated forces on the cartilage.
- Conditions
- Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
- Trial name
- PRMRP FPA CT (NCT05209347)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Sponsor
- University of Iowa
Rheumatoid Arthritis
Anti-TNFα Use During Elective Foot and Ankle Surgery in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a frequent inflammatory arthritis that can lead to severe joint deformity and often requires orthopaedic surgical interventions.
- Trial name
- NCT02242474
- Testing
- Anti-TNF suspended perioperatively, Anti-TNFα continued perioperatively
- Where
- Canada
- Volunteers
- 660 people
- Sponsor
- CHU de Quebec-Universite Laval
Arthrosis, Unspecified, Ankle and Foot
Protracted Effect of the Ultrasound-guided Saphenous Block
This study focuses on optimizing the postoperative pain treatment after major foot and ankle surgery by prolonging the duration of the ultrasound-guided saphenous block.
- Trial name
- PEUSB (NCT02346110)
- Testing
- Bupivacaine-adrenaline, Dexamethasone, Sodium chloride
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Ankle Arthritis
Canadian Orthopaedic Foot and Ankle Society Surgical Treatment of Ankle Arthritis Outcome Study
The purpose of this study is to see if the clinical outcome success rate of Total Ankle Arthroplasty is similar to that of Ankle Arthrodesis over a period of 10 years.
- Trial name
- NCT00552136
- Testing
- Ankle Arthroplasty, Ankle Arthrodesis
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Nova Scotia Health Authority
Knee Osteoarthritis
"Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis"
This research analyzes the effectiveness of Mulligan mobilization in comparison to proprioceptive exercises for treating patients with mild to moderate Knee osteoarthritis whose condition falls under Kellgren and Lawrence grading…
- Trial name
- MWMPETKOA (NCT06971016)
- Testing
- Mulligan Mobilization technique, Proprioceptive Exercises, Traditional Physical therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- National Healthcare Center
Osteoarthritis, Foot
A Comparative Trial of a Minimal-invasive Technique Versus Open Arthrodesis in the Treatment of Midfoot Arthritis
Group A: Patients suffering from midfoot arthritis after failed prior conservative therapy who undergo a reverse distal metatarsal minimal-invasive osteotomy Group B: Patients suffering from midfoot arthritis after failed prior…
- Conditions
- Osteoarthritis, Foot, Osteotomy
- Trial name
- NCT04894578
- Testing
- reverse distal metatarsal minimal-invasive osteotomy, tarsometatarsal fusion
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Baden