Clinical trials: Arthritis Knee
Arthritis of Knee
ROCC Knee Data Collection
This observational study intends to collect efficacy and safety data on ROCC Knee system.
- Trial name
- NCT00758901
- Testing
- Knee Replacement (with ROCC Knee prosthesis)
- Where
- 3 sites in Austria, France and 1 more
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee
The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of FX005 for the treatment of pain in patients with osteoarthritis of the knee.
- Trial name
- NCT01291914
- Testing
- FX005
- Where
- 13 sites in Austria, Canada and 2 more
- Volunteers
- 140 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis, Knee
An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee
The purpose of this study is to identify the dose(s) of IDEA-033 that will provide a meaningful effect for treating osteoarthritis of the knee.
- Trial name
- NCT00211549
- Testing
- IDEA-033
- Where
- 100 sites in United States
- Volunteers
- 875 people
- Sponsor
- IDEA AG
Meniscus; Degeneration, Osteoarthritis, Knee
Treatment of the Medial Meniscus With the NUsurface(R) Meniscus Implant
This is a prospective, multi-center, open label, non-randomized study, evaluating the treating of medial meniscus deficiency with the NUsurface Meniscus Implant.
- Trial name
- NCT01712191
- Testing
- NUsurface Meniscus Implant
- Where
- 10 sites in Belgium, Germany and 4 more
- Volunteers
- 128 people
- Sponsor
- Phoenix Kinetics
Anterior Cruciate Ligament Injury, Osteoarthritis
Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction
The purpose of this study is to evaluate safety and preliminary efficacy of MSB-CAR001 in subjects who have recently undergone an Anterior Cruciate Ligament Reconstruction
- Trial name
- NCT01088191
- Testing
- MSB-CAR001 Combined With Hyaluronan, Hyaluronan
- Where
- Australia
- Volunteers
- 17 people
- Sponsor
- Mesoblast, Ltd.
Osteoarthritis, Rheumatoid Arthritis
Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKA
The study will evaluate the clinical performance of the rotating platform and fixed bearing implants through patient questionnaires, outcomes scoring and radiographic assessment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Other Inflammatory Arthritis, Post-Traumatic Arthritis
- Trial name
- NCT00289107
- Testing
- Total Knee Arthroplasty, Total knee replacement
- Where
- 3 sites in United States
- Volunteers
- 149 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee
The objective of this 2-year study is to evaluate the safety, tolerability and disease modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in overweight and obese subjects with knee…
- Trial name
- ITIC (NCT00565812)
- Testing
- SD-6010
- Where
- 183 sites in United States, Argentina and 12 more
- Volunteers
- 1,457 people
- Sponsor
- Pfizer
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Osteoarthritis
Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant
Study is prospective and multi-center. Study will include 100 to 200 patients across up to 20 sites.The study sites will be located in the United States.The study objective is to evaluate the safety and performance of the…
- Trial name
- iUni (NCT01117571)
- Testing
- iUni® Unicompartmental Knee Resurfacing Device
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Restor3D
Obesity, Overweight
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo.
- Conditions
- Obesity, Overweight, Osteoarthritis, Knee
- Trial name
- AMAZE 6 (NCT07509307)
- Testing
- NNC0487-0111
- Where
- 81 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Osteoarthritis
Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee
A double-blind, randomized, placebo-controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of single injection of RTX-GRT7039 versus placebo in patients who have pain associated with…
- Trial name
- NCT05449132
- Testing
- RTX-GRT7039
- Where
- 81 sites in United States, Denmark and 3 more
- Volunteers
- 466 people
- Sponsor
- Grünenthal GmbH
Knee Osteoarthritis
Sanomechanics® Rehabilitative Technology
Rehabilitative Sanomechanics Method (RSM) of exercise designed to restore normal subperiosteal transmission of in-joint pressures and normalizing contact pressures on cartilages, will reduce pain in the affected joints and…
- Trial name
- NCT05512507
- Testing
- Physical Therapy Program
- Volunteers
- 15 people
- Sponsor
- PolyOrth International
Knee Osteoarthritis
Long-Term Follow-up Study of Subjects With Knee Osteoarthritis Who Had Administered FURESTEM-OA Kit Inj. in K0701 Study
Long-Term Follow-up Study of Subjects with Knee Osteoarthritis who had administered FURESTEM-OA Kit Inj. in K0701 study
- Trial name
- NCT06013306
- Volunteers
- 58 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Knee Osteoarthritis
Oxford UKA and HTO Post-market Clinical Study
The purpose of this study is to compare the performance and safety of medial UKA and HTO in the treatment of AMOA in term of functional outcome, radiographic assessment, range of motion, postoperative complications, revision rate…
- Trial name
- NCT04518111
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zimmer Biomet
Arthritis, Degenerative
3VM for Treatment of Chronic Osteoarthritis Knee Pain
A double-blind, placebo-controlled, randomized dose ranging study for the use of 3VM1001 Cream, 2g three times daily, 3g three times daily, or 3g four times daily for treatment of chronic pain associated with osteoarthritis of…
- Trial name
- NCT03142178
- Testing
- Experimental: 3VM1001 active 2g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 4 times daily
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- CDA Research Group, Inc.
Osteoarthritis of the Knee
Total Knee Arthroplasty Functional Outcomes Study Research Design
The purpose of this study is to obtain patient oriented and clinically oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty.
- Trial name
- NCT02228538
- Testing
- Total knee arthroplasty patients
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Restor3D
Knee Osteoarthritis
Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and…
- Trial name
- NCT05050448
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Joint Disease
Post Market Follow-Up Study of the EVOLUTION® Total Knee Arthroplasty System With Cruciate Sacrificing Inserts
MPO is conducting this PMCF study to evaluate the safety and efficacy of its EVOLUTION® Total Knee Arthroplasty (TKA) components marketed in the EU.
- Trial name
- AMETHYST (NCT02351414)
- Testing
- Total Knee Arthroplasty (EVOLUTION®)
- Where
- 5 sites in United States, Belgium and 3 more
- Volunteers
- 150 people
- Sponsor
- MicroPort Orthopedics Inc.
Knee Osteoarthritis
Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part II
Study objectives: Part 1 TDU11685 To assess in patients with knee Osteoarthritis (OA), the safety, tolerability and pharmacokinetics (PK) of single intra-articular doses of SAR113945.
- Trial name
- NCT01598415
- Testing
- SAR113945
- Where
- 2 sites in Germany
- Volunteers
- 130 people
- Sponsor
- Sanofi
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